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Researchers uncover new therapeutic opportunity in the treatment of malignant melanoma

A team of researchers led by Dr Pierre Close, WELBIO researcher at the ULiège GIGA Institute and Dr Francesca Rapino has uncovered a new therapeutic opportunity in the treatment of malignant melanoma that acquired resistance to targeted therapies.

21 Jun 2018

Scientists develop method to determine metabolic activity of neural networks

During the last decade, neurobiologists's attention has been focused on the study of the functioning of neural networks rather than single nerve cells.

14 Jun 2018

Study uncovers mechanism underlying brain malformation linked to severe epilepsy

One of the most frequent causes of drug-resistant epilepsy, considered a difficult disease to control, is a brain malformation known as focal cortical dysplasia.

16 May 2018

Study uncovers promising new line of attack against aggressive prostate cancer

UC San Francisco researchers have discovered a promising new line of attack against lethal, treatment-resistant prostate cancer. Analysis of hundreds of human prostate tumors revealed that the most aggressive cancers depend on a built-in cellular stress response to put a brake on their own hot-wired physiology.

14 May 2018

Researchers uncover mechanism critical to keeping blood stem cells functional

Hematopoietic stem cells, that form mature blood cells, require a very precise amount of protein to function - and defective regulation of protein production is common in certain types of aggressive human blood cancers.

6 Apr 2018

New $3.2 million grant funds research to advance promising malaria vaccine

The Global Health Innovative Technology Fund has awarded the University of Florida and partners in the United States and Japan $3.2 million to advance a promising vaccine to prevent transmission of malaria.

29 Mar 2018

TSRI scientists discover new pathway to promote mitochondrial function during stress

Scientists at The Scripps Research Institute have discovered a new pathway in cells that promotes mitochondrial function during times of stress, a response that can guard against disease as we age.

15 Mar 2018

TSRI researchers show path to developing treatments for Charcot-Marie-Tooth disease

Scientists at The Scripps Research Institute have now shown a path to developing treatments for disease subtype CMT2D.

8 Mar 2018

Researchers determine cause of difficult-to-control mitochondrial diseases

A Japanese research group has discovered that taurine is conjugated with mitochondrial transfer RNAs (tRNAs), small RNAs that decode genetic information, and that taurine deficiency in tRNA dramatically reduces both mitochondrial protein translation and impairs mitochondrial membrane integrity.

7 Mar 2018

Daffodils may hold secrets of cancer cure

A natural extract from daffodils may help in treatment of cancer find researchers at the Faculty of Sciences at the ULB led by Denis Lafontaine. The team published their research titled, “The Amaryllidaceae Alkaloid Haemanthamine Binds the Eukaryotic Ribosome to Repress Cancer Cell Growth” in the journal Structure that appeared in their latest issue this week.

1 Mar 2018

Fresh insights into depression could pave way for new therapies

Fresh insights into changes in the brain linked to depression could pave the way for new therapies.

27 Feb 2018

Research reveals anti-cancer effects of natural extract from Daffodils

A research describes the anti-cancer effects of a natural alkaloid extracted from Daffodils. Led by Denis Lafontaine, affiliated with the Faculty of Sciences at the ULB, the researchers have discovered that this compound triggers the activation of an anti-tumoral surveillance pathway.

26 Feb 2018

Scientists reveal new insights into mechanism of gene regulation by 'magic spot'

Using an innovative crystallization technique for studying three-dimensional structures of gene transcription machinery, an international team of researchers, led by scientists at Penn State, has revealed new insights into the long debated action of the "magic spot"--a molecule that controls gene expression in Eschericahia coli and many other bacteria when the bacteria are stressed.

24 Feb 2018

Researchers uncover new details about function of enigmatic protein

In a recent study, a research group at MedUni Vienna has published further details about the function of an enigmatic protein. The biological necessity of this protein, which can chemically alter certain building blocks of the genetic information, has been debated for quite a while.

14 Feb 2018

Study reveals how dengue virus replicates without triggering the body's defenses

A new study reveals how dengue virus manages to reproduce itself in an infected person without triggering the body's normal defenses. Duke researchers report that dengue pulls off this hoax by co-opting a specialized structure within host cells for its own purposes, like a lazy roommate sneaking bits of his laundry into the communal wash.

11 Jan 2018

Elevated levels of inflammation marker linked to lower muscle mass

Elevated levels of the inflammation marker CRP in the blood is an underlying cause of the loss of muscle mass in elderly persons, as shown by a new study from örebro University and University of Nottingham.

11 Jan 2018

Researchers reveal how tumor cells disrupt circadian rhythm to survive

Tumor cells use the unfolded protein response to alter circadian rhythm, which contributes to more tumor growth, Hollings Cancer Center researchers at the Medical University of South Carolina find.

28 Dec 2017

Post-workout muscle-building response better in people eating whole eggs than egg whites

People who consume 18 grams of protein from whole eggs or from egg whites after engaging in resistance exercise differ dramatically in how their muscles build protein, a process called protein synthesis, during the post-workout period, researchers report in a new study.

20 Dec 2017

Two studies show how cells adapt to stressors by reprogramming internal signaling networks

In a pair of publications, researchers have shown how cells adapt to stressors--like water loss--by reprogramming their internal signaling networks.