Proteome News and Research

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The proteome is the entire complement of proteins expressed by a genome, cell, tissue or organism. More specifically, it is the expressed proteins at a given time point under defined conditions. The term is a blend of proteins and genome.

Genocea Biosciences, NMRC sign CRADA to develop vaccine against malaria

Genocea Biosciences, a leading vaccine discovery and development company, today announced that it has entered into a Cooperative Research and Development Agreement with the Naval Medical Research Center. NMRC will collaborate with Genocea to identify antigens that will be used in the development of a vaccine candidate against Plasmodium falciparum for the prevention of malaria.

16 Apr 2010

New Prestige Antibodies powered by Atlas Antibodies added to Sigma Life Science's portfolio

Sigma® Life Science, the innovative biological products and services brand of Sigma-Aldrich®, today announced that it has added 2,200 new Prestige Antibodies® powered by Atlas Antibodies to its industry-leading portfolio.

From Atlas Antibodies 29 Mar 2010

Scientists identify two proteins that serve as biomarkers for tracking the spread of colon cancer

Scientists in China are reporting discovery of two proteins present in the blood of people with colon cancer that may serve as the potential biomarkers for accurately predicting whether the disease will spread. Their study is in ACS' Journal of Proteome Research, a monthly publication.

4 Mar 2010

High blood pressure drugs may be useful in preventing and treating diabetic retinopathy: Study

Scientists in Massachusetts are reporting new evidence that certain high blood pressure drugs may be useful in preventing and treating diabetic retinopathy, the leading cause of vision loss in people with diabetes. The study, the largest to date on proteins in the retina, could lead to new ways to prevent or treat the sight-threatening disease, they say.

25 Feb 2010

Five Prime Therapeutics receives milestone payment for selection of therapeutic program

Five Prime Therapeutics, Inc. today announced it received a milestone payment from Centocor Research & Development, Inc. for the selection of a therapeutic that will be pursued for immunology-related indications. Under the collaboration, FivePrime identified multiple potential therapeutic targets through screening its comprehensive proprietary protein library in cell-based assays that were focused on therapeutic pathways underlying specific immune and inflammatory disorders.

24 Feb 2010

PAREXEL International, Proteome Sciences form biomarker alliance

PAREXEL International Corporation, a leading global biopharmaceutical services provider, and Proteome Sciences plc, a leading provider of protein biomarker discovery, validation, and assay development services, today announced the formation of an alliance focused on enhancing PAREXEL's biomarker capabilities for early phase clinical development. PAREXEL is using Proteome Sciences' PS Biomarker Services™ protein and peptide biomarker capabilities to support biopharmaceutical companies in making earlier assessments of new compounds in development.

From Parexel 11 Feb 2010

Compugen discovers CGEN-15001 protein for treatment of autoimmune disorders

Compugen Ltd. announced today the discovery and experimental validation of CGEN-15001 for the treatment of autoimmune disorders.

2 Feb 2010

caprotec bioanalytics launches three new caproKits based on its CCMS technology

caprotec bioanalytics announced today the commercial launch of three new caproKits(TM), enabling the discovery, identification and characterization of proteins belonging to the groups of metallo-proteases, histon-deacetylases and GDP/GTP binding proteins.

27 Jan 2010

Dark chocolates may ease emotional stress

There may well be another important reason for giving your sweetheart sweets for Valentine's Day besides the traditional romantic one: The "chocolate cure" for emotional stress is now getting new support from a clinical trial published online in ACS' Journal of Proteome Research. It found that eating about an ounce and a half of dark chocolate a day for two weeks reduced levels of stress hormones in the bodies of people feeling highly stressed.

23 Jan 2010

Affomix, City of Hope collaborate in exploring next generation sequencing using digital proteomics

Affomix Corporation, a pioneer in high performance antibody technology, announced today a collaboration with City of Hope focused on establishing the clinical utility of “digital proteomics” with next generation sequencers. One of the nation’s top cancer research and treatment centers, City of Hope is a leading provider of molecular diagnostic testing services and an innovator in clinical genetics research.

19 Jan 2010

Treatment for metastatic tumor based on its unique protein makeup

Imagine if treatments for disease could be based not on a patient's diagnosis but instead on the characteristics of their tissue. By identifying and decoding the cryptic messages hidden deep inside the human proteome, scientists and physicians who study personalized medicine are seeking more effective treatments and disease management for patients.

18 Jan 2010

Scientists discover potential biomarkers to predict the spread of colon cancer

Scientists in China are reporting discovery of two proteins present in the blood, of people with colon cancer that may serve as the potential biomarkers for accurately predicting whether the disease will spread.

18 Jan 2010

High blood pressure drugs may be useful in preventing and treating diabetic retinopathy

7 Jan 2010

Affomix to generate antibodies against proprietary targets chosen by Kalgene

Affomix Corporation, a pioneer in the development of automated, high-throughput monoclonal antibody selection technology, announced today that Kalgene Pharmaceuticals Inc. has signed a commercial agreement to have Affomix utilize its Y2HExpress™ technology to select antibodies with potential diagnostic and therapeutic utility in breast cancer. Kalgene Pharmaceuticals Inc. is a private company focused on the development of oncology therapeutics and companion diagnostics.

29 Dec 2009

CGEN-671, a new drug target for multiple epithelial tumors discovered by Compugen

Compugen Ltd. announced today the discovery and experimental validation of CGEN-671, a new drug target for multiple epithelial tumors.

28 Dec 2009

Patients' urine may provide rapid diagnosis of pneumonia

Doctors may soon be able to quickly and accurately diagnose the cause of pneumonia-like symptoms by examining the chemicals found in a patient's urine, suggests a new study led by UC Davis biochemist Carolyn Slupsky.

10 Dec 2009

New protein discovery may serve as potential marker of drug addiction

Scientists are adding additional brush strokes to the revolutionary new image now emerging for star-shaped cells called astrocytes in the brain and spinal cord. Their report, which suggests a key role for astrocytes in morphine's ability to relieve pain and cause addiction, appears online in ACS' Journal of Proteome Research, a monthly publication.

10 Dec 2009

Scientists search for the secrets of how calorie-restricted diets increase longevity

Scientists searching for the secrets of how calorie-restricted diets increase longevity are reporting discovery of proteins in the fat cells of human volunteers that change as pounds drop off.

10 Dec 2009

Scientists discover the potential basis for urine test to diagnose CAP

Scientists are reporting a discovery of the potential basis for a urine test to diagnose community-acquired pneumonia (CAP), a difficult-to-diagnose disease that is the sixth leading cause of death in the United States.

10 Dec 2009

FORMA Therapeutics closes Series B financing to a total of $25.5 million

FORMA Therapeutics today announced that it has closed on a Series B financing that raised a total of $25.5 million. The round was led by new investor Lilly Ventures, with participation from existing investors Novartis Option Fund and Bio*One Capital of Singapore.

1 Dec 2009

Proteome News and Research

Genocea Biosciences, NMRC sign CRADA to develop vaccine against malaria

New Prestige Antibodies powered by Atlas Antibodies added to Sigma Life Science's portfolio

Scientists identify two proteins that serve as biomarkers for tracking the spread of colon cancer

High blood pressure drugs may be useful in preventing and treating diabetic retinopathy: Study

Five Prime Therapeutics receives milestone payment for selection of therapeutic program

PAREXEL International, Proteome Sciences form biomarker alliance

Compugen discovers CGEN-15001 protein for treatment of autoimmune disorders

caprotec bioanalytics launches three new caproKits based on its CCMS technology

Dark chocolates may ease emotional stress

Affomix, City of Hope collaborate in exploring next generation sequencing using digital proteomics

Treatment for metastatic tumor based on its unique protein makeup

Scientists discover potential biomarkers to predict the spread of colon cancer

High blood pressure drugs may be useful in preventing and treating diabetic retinopathy

Affomix to generate antibodies against proprietary targets chosen by Kalgene

CGEN-671, a new drug target for multiple epithelial tumors discovered by Compugen

Patients' urine may provide rapid diagnosis of pneumonia

New protein discovery may serve as potential marker of drug addiction

Scientists search for the secrets of how calorie-restricted diets increase longevity

Scientists discover the potential basis for urine test to diagnose CAP

FORMA Therapeutics closes Series B financing to a total of $25.5 million

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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