Proton Therapy News and Research

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Drug combination may reduce the risk of prostate cancer progression, death

TALAPRO-2, a study led by Neeraj Agarwal, MD, FASCO, demonstrated that using TALZENNA, in combination with XTANDI, may reduce the risk of disease progression or death by 37%.

17 Mar 2023

What are the clinical considerations of proton radiotherapy for individuals with locally advancing breast cancer?

In a recent review published in Current Oncology, researchers highlighted the technical and clinical considerations for proton radiotherapy delivery for individuals with locally advancing breast malignancies.

1 Mar 2023

Analysis finds more than 100 new genetic risk factors strongly linked to colorectal cancer

A comprehensive analysis of more than 100,000 colorectal cancer (CRC) cases, led by researchers at the Fred Hutchinson Cancer Center in Seattle and 200 scientific collaborators worldwide, has identified more than 100 new genetic risk factors strongly linked with the disease.

20 Dec 2022

A-HIPI decision model can predict survival in adults with advanced-stage Hodgkin lymphoma

Investigators from Rutgers Cancer Institute of New Jersey, the state's only NCI-designated Comprehensive Cancer Center and leading cancer program along with Tufts Medical Center in Boston, developed and validated the Advanced-stage Hodgkin lymphoma International Prognostication Index (A-HIPI).

12 Dec 2022

Study finds a positive impact of exercise on the gut microbiome of cancer patients

Regular physical activity can extend colorectal cancer patients' lives. In a first-ever study, scientists looked at the impact of exercise on the gut microbiome of cancer patients and reported a positive association.

14 Nov 2022

HPV vaccine rates in Utah increase by more than 16% among young men and women, CDC data reveals

When life should have been ripe with possibilities, Mandy Murry instead faced a devastating diagnosis. Murry was diagnosed with cervical cancer when she was 22.

4 Nov 2022

Researchers streamline way to manufacture CAR T-cells in just 24 hours

Researchers at University Hospitals (UH) Seidman Cancer Center and a biotech start-up company have developed a streamlined way to manufacture CAR T-cells for immunotherapy treatment in just 24 hours – an improvement over the team's previous benchmark of eight days and commercial suppliers that typically take three weeks.

25 Oct 2022

FLASH radiotherapy may hold promise as a potential treatment for tough-to-kill tumors

FLASH radiation treatment – which delivers therapeutic doses of radiation in a fraction of a second – may hold promise as a potential treatment for tough-to-kill tumors, a first-in-human study in a small number of people with bone cancer suggests.

24 Oct 2022

Systematic differences in electronic health record data can negatively affect patient care

Patients from historically medically underserved groups, including patients of color and those who are Spanish-speaking, have less cancer family history information available to them. In addition, existing health records are less comprehensive, according to a study published October 4 in the Journal of the American Medical Association Network Open.

6 Oct 2022

Research may lead to safer ways to care for patients impacted by blood clots

A nanoparticle therapy developed by investigators at University Hospitals (UH) and Case Western Reserve University targets overactive neutrophils, a specific kind of white blood cell, to prevent almost all types of blood clots while causing no increased risk for bleeding.

30 Sep 2022

Frequent aspirin use associated with lower ovarian cancer risk in people with multiple risk factors

Frequent aspirin use is linked with lower ovarian cancer risk in individuals with multiple risk factors, according to a new study published in the Journal of Clinical Oncology.

26 Jul 2022

Scientists use single cell techniques to uncover a central dichotomy for colorectal cancer cells

A team of clinician-scientists and scientists, led by the National Cancer Centre Singapore and A*STAR's Genome Institute of Singapore together with collaborators in Europe and South Korea, used single-cell techniques to uncover a central dichotomy for colorectal cancer cells, leading to a proposed update of the classification system for the disease.

1 Jul 2022

Researchers evaluate how hundreds of different mutations impact key function of breast cancer gene

Inherited mutations in the BRCA1 gene can significantly increase a person's risk of breast and ovarian cancer-;but not every mutation in the gene is harmful.

3 Jun 2022

Intestinal microbiome may contribute to the pathogenesis of MSI colon cancers, study suggests

Investigators from Rutgers Cancer Institute of New Jersey, New Jersey's only National Cancer Institute- Designated Comprehensive Cancer Center, led a collaborative study to examine the patterns of druggable oncogenic fusions in colon cancer specimens including microsatellite-stable and unstable (MSI) tumors.

19 May 2022

Irradiation of tumors with laser protons tested for the first time

Irradiation with fast protons is a more effective and less invasive cancer treatment than X-rays. However, modern proton therapy requires large particle accelerators, which has experts investigating alternative accelerator concepts, such as laser systems to accelerate protons.

14 Mar 2022

Penn Medicine receives $12.3 million NIH grant to study FLASH radiotherapy for cancer

With more than $12 million in new funding from the National Institutes of Health, the Abramson Cancer Center at the University of Pennsylvania will build on its preclinical research of an emerging form of radiation that provides ultra-fast doses-;of under a second, compared to several minutes with conventional radiation-;and shows promise of greater protection of normal tissue, thereby minimizing toxic effects to the body.

1 Mar 2022

Researchers report a new, more efficient way to grow breast cancer models

For years, researchers at Huntsman Cancer Institute at the University of Utah have honed a process of developing breast cancer models using tumors donated by breast cancer patients, which they then implant into mice as a way to study the tumor's behavior.

28 Feb 2022

Researchers find potential new strategy to treat metastatic form of intra-abdominal cancer

Researchers from the National Cancer Centre Singapore (NCCS) have found a potential new strategy to treat peritoneal carcinomatosis, a metastatic form of intra-abdominal cancer, where patients are presented with limited treatment options and poor overall survival.

15 Feb 2022

Addition of hormone therapy to radiotherapy treatments improves survival in prostate cancer patients

Prostate cancer is the leading cause of cancer in men worldwide, and radiotherapy is one of the common forms of treatment.

18 Jan 2022

Scientists describe dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

Clinician scientists and scientists from the National Cancer Centre Singapore and A*STAR's Genome Institute of Singapore, in collaboration with Singapore General Hospital, the National University Health System, Duke-NUS Medical School, Nanyang Technological University, and collaborators from China, Malaysia, Thailand and the Philippines, have described a dynamic genomic landscape of tumour heterogeneity in hepatocellular carcinoma (HCC).

13 Dec 2021