Psoriatic Arthritis News and Research

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Like rheumatoid arthritis (RA), psoriatic arthritis is a chronic inflammatory disease of the joints and connective tissue. The disease causes joint pain and swelling that can lead to crippling along with inflamed and irritated scaly red patches of skin throughout the body. It is a progressive and debilitating disease and because there are no treatments specifically approved for psoriatic arthritis, doctors often use therapies approved for RA, including nonsteroidal anti-inflammatory drugs (NSAIDs) and disease modifying anti-rheumatic drugs (DMARDs). However, no DMARDs are currently approved for use in psoriatic arthritis. There are approximately 300,000 patients with psoriatic arthritis in the United States and the disease affects both men and women most commonly between the ages 30 and 50. Psoriatic arthritis patients are generally treated by rheumatologists and dermatologists.

New insights into the exacerbation of psoriasis through specific genetic defects

The inflammatory potential of tissue-resident regulatory T cells in a murine gain of function model.

27 Mar 2024

ANU scientists uncover gene mutation driving psoriasis and psoriatic arthritis

Scientists from The Australian National University (ANU) have discovered a gene mutation is responsible for causing psoriasis – a chronic inflammatory skin disease that causes patients to develop red, scaly and itchy patches across their body.

25 Mar 2024

Pregnant women with autoimmune conditions at a greater risk of developing adverse pregnancy outcomes, study suggests

Researchers analyzed systematic reviews conducted on the association between autoimmune diseases and pregnancy outcomes.

8 Mar 2024

Is there a higher risk of depression among specific populations of patients with rheumatoid arthritis?

Researchers assessed the risk of depression following the diagnosis of rheumatoid arthritis (RA).

8 Mar 2024

Study shows nuanced pregnancy outcomes for pregnant individuals with autoimmune disease

For many aspiring mothers with autoimmune disease, pregnancy can be daunting and full of unknowns. In some cases, those suffering from specific autoimmune conditions have chosen to forego pregnancy altogether due to concerns about their disease treatments and adverse pregnancy outcomes.

1 Feb 2024

Study finds no fertility decline in men with inflammatory joint disease

Men with inflammatory joint disease, such as rheumatoid arthritis, are less likely to be childless and have more children than their healthy peers, suggests research published online in the Annals of the Rheumatic Diseases.

22 Jan 2024

New treatment option for hand osteoarthritis identified

Relief could be on the way for people with painful hand osteoarthritis after a Monash University and Alfred Health-led study found an affordable existing drug can help. Until now there has been no effective treatment.

12 Oct 2023

Researchers call for urgent improvement in pain management for inflammatory arthritis patients

Researchers from Keele University's School of Medicine have found that analgesic medicines - commonly known as "painkillers" - are widely prescribed to people with inflammatory arthritis across England despite little research evidence that they improve pain for these patients, and studies showing they can cause serious side-effects.

12 Oct 2023

Is there an association between psoriasis onset and risk of autoimmune disease?

Researchers evaluated new-onset autoimmune disease risk among individuals with new-onset psoriatic illness.

9 Oct 2023

Study sheds light on potential mechanism by which psoriasis increases cardiovascular risk

In the largest study to date exploring the relationship between severe psoriasis and coronary microvascular dysfunction, researchers have found further evidence that patients with severe psoriasis are at higher cardiovascular risk.

20 Sep 2023

Multi-omics study offers insights into psoriasis treatment

Researchers use a multi-omics approach combining immune cell-enriched scRNA-seq, microarray analysis, and immunohistochemistry to elucidate the translational role of anti-IL-17A in suppressing the autoimmune functions of T17 cells, thereby effectively treating human psoriasis.

14 Sep 2023

Herring roe oil's potential in psoriasis treatment

Researchers investigated the use of herring row oil to treat psoriasis, a non-communicable skin disease.

12 Sep 2023

Is DNA methylation the missing link in diagnosing and treating psoriasis and psoriatic arthritis?

Researchers across Europe have delved into the DNA methylation patterns in CD4+ T-cells of psoriasis and psoriatic arthritis (PsA) patients, unveiling potential new biomarkers for these conditions. Their study suggests that these unique profiles could serve as both diagnostic and prognostic tools, although further validation is needed for real-world clinical application.

10 Sep 2023

Scientists elucidate mechanism behind early loss of vaccination protection in people with autoimmune disease

People who are treated with TNF-α inhibitors for their autoimmune disease such as Crohn's disease or rheumatoid arthritis lose their vaccination protection significantly earlier than average.

7 Sep 2023

The causal effect of gut microbiota on psoriasis

The potential relationship between gut microbiota and different subtypes of psoriasis.

22 Aug 2023

Can nutritional interventions positively impact psoriasis severity?

Improvement in psoriasis (Ps) through nutritional strategies.

15 Aug 2023

New tool can identify psoriasis patients at risk for psoriatic arthritis

In research published in Arthritis & Rheumatology, investigators developed and validated a tool called PRESTO that identifies patients with psoriasis who face an elevated risk for developing psoriatic arthritis and may therefore benefit from preventive therapies.

9 Aug 2023

Is COVID-19 vaccination linked to psoriasis emergence or flare-ups?

Researchers explored the relationship between COVID-19 vaccination and psoriasis onset or exacerbation.

7 Aug 2023

ICI therapy linked to unique immune response in arthritis

Immune checkpoint inhibitor (ICI) therapies used to treat cancer come with the risk of adverse autoimmune responses, including arthritis that can persist for years and require joint replacement surgery.

1 Aug 2023

New EULAR points-to-consider can help identify people at risk of psoriatic arthritis

The transition from psoriasis to PsA - and the early diagnosis of PsA - is of considerable scientific and clinical interest. People typically have psoriatic skin disease for a decade or more before they begin to experience the joint involvement of PsA.

17 Jul 2023