Pulmonary Artery News and Research

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No added benefit proven for pulmonary arterial hypertension drug, IQWiG finds

Selexipag is approved for long-term treatment of pulmonary arterial hypertension (PAH) in adults with moderate to severe symptoms.

7 Oct 2016

NCDR provides data to study appropriate use of oral anticoagulant therapy

The American College of Cardiology's National Cardiovascular Data Registry was the source of data for research published throughout 2016, including a study examining if atrial fibrillation patients are being prescribed oral anticoagulants, how appropriate use criteria correlates to angioplasty rates and the variation among racial groups for revascularization procedures.

30 Sep 2016

Biomedical engineers develop artificial blood vessels capable of growth within recipient

In a groundbreaking new study led by University of Minnesota biomedical engineers, artificial blood vessels bioengineered in the lab and implanted in young lambs are capable of growth within the recipient.

27 Sep 2016

AACN Practice Alert offers detailed checklist for aspiration prevention in tube-fed patients

Aspiration among critically ill patients may often be subtle or even silent, but that doesn't mean it's insignificant.

16 Sep 2016

Major trial to test new surgical approach for patients with lung cancer

The University of Montreal Hospital Research Centre is launching a major international clinical trial to test a minimally invasive and safer surgical approach for patients with lung cancer: video-assisted thoracoscopic (VATS) lobectomy with ultrasonic pulmonary artery sealing.

11 Jul 2016

Right ventricular echocardiography predicts targeted therapy outcome in PAH

Echocardiography re-assessment of right ventricular function after targeted therapy is sufficient to predict subsequent prognosis in patients with pulmonary arterial hypertension, say researchers.

15 Jun 2016

Reduced RV functional reserve may explain poor SSc-PAH outcomes

Patients who develop pulmonary arterial hypertension as a consequence of systemic sclerosis have poorer right ventricular functional reserve than those with idiopathic disease, research published in Circulation shows.

9 Jun 2016

Researchers detect vascular matrix stiffening during early stages of pulmonary hypertension

Pulmonary hypertension is an abnormal elevation of pressure in the pulmonary circulation that results in stress on the heart and remodeling of blood vessels in the lung.

3 Jun 2016

First-ever clinical trial of bioabsorbable cardiovascular device in children shows promise

Current cardiovascular valve or blood vessel implants are generally associated with a number of complications, have limited efficacy over time, and may necessitate repeated interventions over a patient's lifetime, especially when implanted in a young child.

18 May 2016

Arterial switch to 12 o'clock position linked to myocardial ischaemia risk in adolescence

Arterial switch to the 12 o'clock position is associated with abnormal coronary perfusion in adolescence, reveals research presented today at EuroCMR 2016.1 Babies born with transposition of the great arteries (TGA) undergo the arterial switch operation in the first days of life.

13 May 2016

More evidence for combination therapy benefits in PAH

Another meta-analysis adds to evidence of increased benefits for patients with pulmonary arterial hypertension who are given combination therapy.

6 May 2016

Detailed digital models of human organs could bring substantial benefits to clinical trials

Computer simulations of disease processes and detailed digital models of our organs could provide more accurate monitoring and outcome measurements for clinical trials, according to research being presented in Sheffield today.

5 May 2016

Stereotactic body radiation therapy for NSCLC patients may raise non-cancer mortality risk

Researchers have found that treating patients who have early stage non-small cell lung cancer (NSCLC) with a type of radiotherapy called stereotactic body radiation therapy (SBRT) is associated with a small but increased risk of death from causes other than cancer.

2 May 2016

Clinicians describe placement of first implantable hemodynamic monitor in single ventricle Fontan anatomy

While the Fontan procedure has improved the short- and mid-term outcomes for patients born with single ventricle anatomy, long-term complications of Fontan circulation include heart failure. These complications are thought to be secondary to elevated central venous pressure, chronic venous congestion and low cardiac output.

29 Apr 2016

BMPR2 mutations affect outcomes of PAH patients

Mutations in the bone morphogenetic protein receptor type II gene affect not only the risk of developing pulmonary arterial hypertension but also the severity and outcomes of the disease, shows a meta-analysis of individual patient data.

12 Apr 2016

Tricuspid regurgitation tied to outcomes in PAH patients

Tricuspid regurgitation progresses in line with right ventricular remodelling and increasing pulmonary artery systolic pressure in patients with pulmonary arterial hypertension, research shows.

10 Mar 2016

Regulatory immune cells compromised in PAH

Research suggests that regulatory T cells may play a part in all subtypes of pulmonary arterial hypertension.

10 Mar 2016

CHLA cardiologists perform rare fetal cardiac intervention procedure

Last August, when Children's Hospital Los Angeles cardiologists confirmed that the heart of a 27-week-old fetus suffered from a critical cardiac condition that prevented blood returning from the fetus's lungs from circulating back into the body, they told the parents that their child faced certain open-heart surgery after birth. Even worse, babies born with this very rare condition—hypoplastic left heart syndrome (HLHS) with restrictive atrial septum—have a 50 percent neonatal mortality rate.

27 Feb 2016

BMPR2 mutations affect outcomes of PAH patients

4 Feb 2016

Study findings may help explain why risk of stroke changes after menopause

Risk of stroke in women may come down to a compound the body produces from estrogen known as 2-methoxyestradiol (2-ME). Furthermore, the compound's therapeutic potential may extend beyond treating stroke in women to healing brain injuries in men, a new study in American Journal of Physiology—Endocrinology and Metabolism reports.

20 Jan 2016

Pulmonary Artery News and Research

No added benefit proven for pulmonary arterial hypertension drug, IQWiG finds

NCDR provides data to study appropriate use of oral anticoagulant therapy

Biomedical engineers develop artificial blood vessels capable of growth within recipient

AACN Practice Alert offers detailed checklist for aspiration prevention in tube-fed patients

Major trial to test new surgical approach for patients with lung cancer

Right ventricular echocardiography predicts targeted therapy outcome in PAH

Reduced RV functional reserve may explain poor SSc-PAH outcomes

Researchers detect vascular matrix stiffening during early stages of pulmonary hypertension

First-ever clinical trial of bioabsorbable cardiovascular device in children shows promise

Arterial switch to 12 o'clock position linked to myocardial ischaemia risk in adolescence

More evidence for combination therapy benefits in PAH

Detailed digital models of human organs could bring substantial benefits to clinical trials

Stereotactic body radiation therapy for NSCLC patients may raise non-cancer mortality risk

Clinicians describe placement of first implantable hemodynamic monitor in single ventricle Fontan anatomy

BMPR2 mutations affect outcomes of PAH patients

Tricuspid regurgitation tied to outcomes in PAH patients

Regulatory immune cells compromised in PAH

CHLA cardiologists perform rare fetal cardiac intervention procedure

BMPR2 mutations affect outcomes of PAH patients

Study findings may help explain why risk of stroke changes after menopause

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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