Pulmonary Artery News and Research

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New blood biomarkers could lead to better evaluation of treatment for patients with PAH

New blood biomarkers reflecting vasoreactivity in lung blood vessels of patients with heart- and lung disease, can lead to simplified diagnostics and better evaluation of treatment for patients with the condition pulmonary arterial hypertension (PAH).

18 Jan 2016

RV glucose metabolism changes associated with RV function

The rate of myocardium glucose utilisation in the right ventricle correlates with its function and could be used to monitor treatment effects in patients with pulmonary arterial hypertension, findings indicate.

11 Dec 2015

Early promise for pulmonary artery denervation in PAH patients

Pulmonary artery denervation is feasible and may reduce pulmonary arterial pressure in patients with pulmonary arterial hypertension, phase II findings suggest.

11 Dec 2015

Mallinckrodt announces approval of INOmax for cardiovascular surgery in Australia and Japan

Mallinckrodt plc, a leading specialty biopharmaceutical company, today announced that INOmax (nitric oxide) for inhalation has received regulatory approval in Australia and Japan for pulmonary hypertension in conjunction with heart surgery.

30 Oct 2015

Scientists compile complete genetic information of people affected by PAH

The genetic architecture of a debilitating and potentially fatal vascular disease has for the first time been detailed in its entirety, providing clinicians with the comprehensive data needed to improve diagnosis and deliver more personalised patient care.

25 Sep 2015

Arterial shunt in hybrid palliation better for hypoplastic left heart syndrome treatment

Children born with the major congenital heart defect hypoplastic left heart syndrome (HLHS) often must undergo a series of corrective surgeries beginning at birth. While most have the standard three-stage Norwood procedure, a hybrid strategy has been introduced to offset some disadvantages associated with the Norwood surgeries. In a report in The Journal of Thoracic and Cardiovascular Surgery, investigators compare whether outcomes can be improved if an arterial shunt is used as a source of pulmonary blood flow rather than the more conventional venous shunt as part of the hybrid strategy of HLHS surgical reconstruction.

14 Aug 2015

Study reveals benefit of early screening for vascular disorder patent ductus arteriosus among preterm infants

Among extremely preterm infants, early screening for the vascular disorder patent ductus arteriosus before day 3 of life was associated with a lower risk of in-hospital death and pulmonary hemorrhage, but not with differences in other severe complications, according to a study in the June 23/30 issue of JAMA.

24 Jun 2015

Mount Sinai cardiologists implant microchip sensors to better monitor patients with heart failure

Cardiologists at The Mount Sinai Hospital have begun implanting tiny, state-of-the-art microchip sensors in patients with advanced heart failure to better monitor symptoms and reduce their chances of returning to the hospital.

12 Jun 2015

Physicians at UH Case Medical Center implant revolutionary device to treat right ventricular heart disease

University Hospitals Case Medical Center physicians in the Harrington Heart & Vascular Institute were the first in the state of Ohio to implant a revolutionary device to treat right ventricular heart disease.

5 Jun 2015

Early intensive epoprostenol yields best haemodynamic outcomes in PAH

Patients with pulmonary arterial hypertension achieve greater improvements in right heart haemodynamics if epoprostenol is given rapidly and at a high dose, research suggests.

15 May 2015

Meta-analysis supports ambrisentan efficacy

A meta-analysis supports the efficacy of ambrisentan in patients with pulmonary arterial hypertension.

15 May 2015

Selten Pharma's SPI-026 granted FDA Orphan Drug Designation for treatment of PAH

Selten Pharma, Inc., a privatively held biopharmaceutical company focused on the development and commercialization of therapies for the treatment of rare diseases, announced today that its lead compound tacrolimus (SPI-026) has been granted Orphan Drug Designation by the U.S. Food & Drug Administration for the treatment of pulmonary arterial hypertension (PAH).

18 Mar 2015

Combining CT measurements assists pulmonary hypertension prediction

Research suggests that combining pulmonary artery and ventricular measurements improves the chances of identifying pulmonary hypertension in patients undergoing computed tomography pulmonary angiography.

13 Mar 2015

Metabolic derangement may facilitate cell proliferation in PAH

An enzyme that facilitates modification of proteins via a glucose metabolism pathway may promote cell proliferation in the lung tissue of patients with idiopathic pulmonary arterial hypertension, say researchers.

13 Mar 2015

Vectorious Medical Technologies closes $5 million financing round

Vectorious Medical Technologies, an Israeli company developing a novel cardiac monitoring system for patients suffering from congestive heart failure (CHF), announced today that it has closed a $5 million financing round.

26 Feb 2015

Surgical procedure for acute pulmonary embolism may actually prevent more deaths

A surgical procedure that was virtually abandoned in the 1950s because of its high mortality rates in trying to save patients with acute pulmonary embolism may actually prevent more deaths in severely ill patients than current drug therapies alone, according to a new analysis of cases conducted in the North Shore-LIJ Health System over the past decade.

11 Feb 2015

CT measures can refine PAH prognosis

Structural features identifiable on computed tomography pulmonary angiography can provide prognostic information for patients with pulmonary arterial hypertension, say UK researchers.

16 Jan 2015

FDA approves AbbVie's VIEKIRA PAK for treatment of patients with GT1 HCV infection

The U.S. Food and Drug Administration has approved AbbVie's VIEKIRA PAK, an all-oral, interferon-free treatment, with or without ribavirin (RBV), for the treatment of patients with chronic genotype 1 (GT1) hepatitis C virus (HCV) infection, including those with compensated cirrhosis.

21 Dec 2014

Noninvasive PAH diagnosis on the horizon

Measuring the duration of vortical blood flow in the main pulmonary artery allows accurate estimation of pulmonary blood pressure and diagnosis of pulmonary arterial hypertension, say researchers.

3 Dec 2014

UCSD engineers propose new single-ventricle heart surgery for children

Engineers at the University of California, San Diego, are proposing a new surgical intervention for children born with a single ventricle in their heart--instead of the usual two. The new approach would potentially reduce the number of surgeries the patients have to undergo in the first six months of life from two to just one. If successful, it would also create a more stable circuit for blood to flow from the heart to the lungs and the rest of the body within the first days and months of life.

6 Nov 2014