Pulmonary Hypoplasia News and Research

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Pulmonary hypoplasia refers to a condition where one or both of a baby’s lungs do not develop properly in the womb. Usually, the condition is secondary to another health problem that limits lung development. This not only affects the baby’s ability to breathe, but causes heart dysfunction, difficulty feeding, poor hearing and overall poor development.

New study highlights risks of anti-ERBB2 cancer drugs during pregnancy

Study finds that anti-ERBB2 inhibitors used in breast cancer treatment pose significant risks to pregnancy and fetal health, including higher likelihoods of congenital defects and intrauterine growth restriction. Researchers recommend careful monitoring and possibly discontinuing these drugs during pregnancy despite their effectiveness against cancer.

29 Oct 2023

Report reveals differences in non-Hispanic black and white infant mortality rates in the US

The jama Pediatrics recently published new research on non-Hispanic black and white infants, the report analyzed the trends in overall and cause-specific infant mortality rates in the US population. According to a 2017 report from the US Centers for Disease Control and Prevention, US infant mortality rates in the past 10 years have decreased by 15%.

4 Jul 2017

RAC1 protein plays crucial role in proper development of mammalian lung

A study by researchers from The Saban Research Institute of Children's Hospital Los Angeles reveals a promising therapeutic target for improving lung function in infants.

21 Oct 2016

CHOP launches Fetal Neuroprotection and Neuroplasticity Program

The Children's Hospital of Philadelphia today launched the Fetal Neuroprotection and Neuroplasticity Program. Building on growing evidence of the interaction of heart disease and brain development in the fetus, this Program will systematically investigate innovative therapies to protect brain development and to prevent brain injury as early as possible before birth.

26 Jun 2014

ECMO can be used on neonates with severe respiratory failure until lung transplantation, say scientists

Adults with end-stage respiratory failure and pulmonary hypertension requiring ECMO (extracorporeal membrane oxygenation) have been "bridged" toward lung transplantation with novel lung assist devices such as the Novalung.

7 May 2013

FETO improves infant survival rate in severe cases of congenital diaphragmatic hernia

A new study published in the journal Ultrasound in Obstetrics & Gynecology reveals that fetal tracheal occlusion (FETO) improves infant survival rate in severe cases of congenital diaphragmatic hernia (CDH).

14 Dec 2011

New discoveries about role of blood vessels in early lung development

A research team at The Saban Research Institute of Children's Hospital Los Angeles has made critical new discoveries about the role of blood vessels in guiding early lung development, especially in the essential, highly reproducible branching pattern of lung airways.

4 Jun 2011