Quinine News and Research

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Old letters provide insight into Spanish flu pandemic horror

An archive of letters written by those who survived the Spanish flu pandemic at the start of the last century shows what it was actually like to live during that time. The Spanish flu pandemic killed over 250,000 people in Britain alone and worldwide it wiped out a population of over 100 million.

23 Sep 2018

Scientists discover protein crucial for activating inflammation

Researchers from the University of Illinois at Chicago have identified a protein that is crucial for activating inflammation -; both the good kind of inflammation that leads to healing wounds and fighting infection, as well as excessive inflammation where the immune system can damage tissues and organs.

27 Jun 2018

Daffodils may hold secrets of cancer cure

A natural extract from daffodils may help in treatment of cancer find researchers at the Faculty of Sciences at the ULB led by Denis Lafontaine. The team published their research titled, “The Amaryllidaceae Alkaloid Haemanthamine Binds the Eukaryotic Ribosome to Repress Cancer Cell Growth” in the journal Structure that appeared in their latest issue this week.

1 Mar 2018

Research reveals anti-cancer effects of natural extract from Daffodils

A research describes the anti-cancer effects of a natural alkaloid extracted from Daffodils. Led by Denis Lafontaine, affiliated with the Faculty of Sciences at the ULB, the researchers have discovered that this compound triggers the activation of an anti-tumoral surveillance pathway.

26 Feb 2018

Fetal alcohol exposure reduces taste system's responsiveness to bitter flavor and burning sensation

A new study suggests that fetal alcohol exposure reduces the taste system's responsiveness to the bitter flavor and burning sensation of many varieties of alcoholic beverages.

18 May 2017

EPFL scientists develop new antibody-linked biosensor to track drug concentration in the blood

Being able to monitor drug concentration in the blood of a patient is an important aspect of any pharmaceutical treatment. However, this requires equipment and facilities that are often missing from field healthcare in developing countries, but also inhibits the quality of life for patients elsewhere.

16 May 2017

Study reveals safety data for using antimalarials during first trimester of pregnancy

Malaria is more common and severe in pregnant women, increasing their risk of miscarriage and other adverse outcomes. The adverse consequences of malaria in pregnancy require prompt, safe, and effective treatment.

3 May 2017

Scientists unravel novel protein catalysts that can direct biosynthesis of hapalindole-type alkaloids

Alkaloids are natural nitrogen-containing compounds produced by plants and microbes. These molecules, such as morphine and quinine, are important human medicines.

22 Feb 2017

Turing Pharmaceuticals emphasizes continued availability of Daraprim

Turing Pharmaceuticals AG, a privately-held biopharmaceutical company focused on developing and commercializing innovative treatments for serious diseases and conditions, today emphasizes the continued availability of Daraprim and cautions healthcare providers of proposed alternatives to Daraprim.

20 Dec 2015

Turing Pharmaceuticals acquires rights to market Daraprim (pyrimethamine) in the U.S.

Turing Pharmaceuticals AG today announced that it has acquired the exclusive rights to market Daraprim (pyrimethamine) in the U.S. from Impax Laboratories, Inc. The acquisition by Turing is part of a strategic effort focused on treatments for toxoplasmosis and other serious infectious diseases. The company also announced plans to invest in the development of new drug candidates for toxoplasmosis.

10 Aug 2015

Lab-on-paper technique could help detect low quality antimalarial drugs

Access to high-quality medicine is a basic human right, but over four billion people live in countries where many medications are substandard or fake. Marya Lieberman of the Department of Chemistry and Biochemistry at the University of Notre Dame and Abigail Weaver a postdoctoral associate in the University's Department of Civil Engineering and Environmental and Earth Sciences took up the challenge of how people in developing countries could detect low quality antimalarial drugs without expensive equipment and without handling dangerous chemicals.

21 Apr 2015

Malaria parasites with Ap2mu gene mutation less sensitive to antimalarial drug artemisinin

Early indicators of the malaria parasite in Africa developing resistance to the most effective drug available have been confirmed, according to new research published in Antimicrobial Agents and Chemotherapy.

20 Apr 2015

New study shows nicotine exposure promotes alcohol dependence

Why do smokers have a five to ten times greater risk of developing alcohol dependence than nonsmokers? Do smokers have a greater tendency toward addiction in general or does nicotine somehow reinforce alcohol consumption? Now, a study led by scientists at The Scripps Research Institute helps provide insight into these questions, showing that, in rat models, nicotine exposure actually promotes alcohol dependence.

16 Apr 2015

TSRI Scientists find that nicotine use increases compulsive alcohol consumption

15 Apr 2015

Study sheds new light on nighttime leg cramps

Nighttime leg cramps commonly affect adults over the age of 50, but are also known to occur in younger adults and children. While their cause is unknown, a study from the University of Alberta's Faculty of Medicine & Dentistry is shedding new light on the painful condition.

28 Jan 2015

New genes involved in taste perception effective in weight loss and improve quality of life

New understanding of the genes involved in taste perception and food preferences could lead to personalised nutrition plans effective not just in weight loss but in avoiding diseases such as cancer, depression, and hypertension, Italian researchers will tell the annual conference of the European Society of Human Genetics (ESHG) today (Monday).

2 Jun 2014

Researchers explore new strategy to defeat drug-resistant strains of malaria

Malaria is one of the most deadly infectious diseases in the world today, claiming the lives of over half a million people every year, and the recent emergence of parasites resistant to current treatments threatens to undermine efforts to control the disease. Researchers are now onto a new strategy to defeat drug-resistant strains of the parasite. Their report appears in the journal ACS Chemical Biology.

15 Jan 2014

Study explains how sensory input impacts fruit flies' decisions about sweet taste

Fruit flies have a lot to teach us about the complexity of food. Like these tiny little creatures, most animals are attracted to sugar but are deterred from eating it when bitter compounds are added.

29 Aug 2013

Scientists identify circuitry in brain that drives compulsive drinking in rats

A research team led by scientists from the Ernest Gallo Clinic and Research Center at the University of California, San Francisco has identified circuitry in the brain that drives compulsive drinking in rats, and likely plays a similar role in humans.

23 Jul 2013

New hope for treating, preventing malaria

Scientists at Oregon Health & Science University and the Portland VA Medical Center have developed a drug that may represent one of the world's best hopes for treating and preventing malaria - a disease that kills more than one million people each year.

22 Mar 2013