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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

The approved dose of ivermectin alone not useful in treating COVID-19

A new paper published on the preprint server medRxiv in April 2020 shows that the use of the already approved drug ivermectin in clinical trials to treat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)s not feasible. This contradicts earlier reports of its ability to suppress the virus in vitro.

27 Apr 2020

Researchers develop new app to track the COVID-19 pandemic

To respond to the spread of the new coronavirus, public health authorities need to know who's getting sick. Now, a new app, developed through an unusual partnership, empowers nearly anyone in the United States to share their health status.

27 Apr 2020

SARS-CoV-2 readily infects human intestinal cells in a laboratory model

A new Dutch study available on bioRxiv uses differentiated human small intestinal organoids in vitro to demonstrate that intestinal epithelium supports the replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and elicits a strong generic immune response.

27 Apr 2020

Research provides insights into how Zika virus can spread through sexual contact

Zika virus is capable of replicating and spreading infectious particles within the outermost cells lining the vaginal tract, according to new research. The findings provide the first molecular-level insights into how the virus can move from person to person through sexual contact.

27 Apr 2020

Researchers re-purpose cancer-fighting artificial antibodies for COVID-19

Researcher Paula Bates, John Trent, and Don Miller developed a therapeutic drug that could potentially block the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) responsible for the COVID-19 pandemic. Their research was initially aimed at helping patients suffering from multiple types of cancer.

27 Apr 2020

Recombinant protein produces neutralizing COVID-19 antibodies in primate model

A new study reports the induction of high levels of neutralizing antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus causing the current pandemic of COVID-19. This promising finding was reported on the preprint server bioRxiv on April 2020.

26 Apr 2020

Microclimate and turbulent wind can influence COVID-19 spread over long distances

Respiratory particles exhaled after a sneeze can be transported by the turbulent wind more than three times further than current social or physical distancing measures recommend, reports a new study from Chile available on the preprint server medRxiv.

26 Apr 2020

Mapping complex peripheral immune response to severe COVID-19

In a recent article publicly available at medRxiv, researchers from Stanford have presented a single-cell atlas of the peripheral immune response to coronavirus disease (COVID-19), highlighting pertinent immunological features associated with the severe forms of the disease.

26 Apr 2020

New brain cell models created to evaluate therapies for Sanfilippo C syndrome

The Sanfilippo syndrome type C is a severe neurodegenerative disease which appearws during the first years of life and for which there is no treatment yet.

24 Apr 2020

Goblet cells in the human nasal passage may play key role in enabling COVID-19 infections

Two significant international studies involving hundreds of scientists, including a human geneticist at the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest that specific cells in the human nasal passage shaped like a champagne glass, known as goblet cells, may play a significant role in enabling COVID-19 infections.

24 Apr 2020

Researchers report promising Phase 1 results for first oral polio vaccine in 50 years

Before being halted due to the COVID-19 pandemic, a relentless vaccination campaign had nearly succeeded in eradicating polio from the world.

24 Apr 2020

First COVID-19-related clinical trial to start in Germany

German regulators have approved the first clinical trial of a coronavirus vaccine. Developed by BioNTech SE, an immunotherapy company, and Pfizer, a pharmaceutical company, the potential coronavirus vaccine has completed pre-clinical studies in Germany.

24 Apr 2020

Research looks at best ways to tackle coronavirus crisis

A new study published in the journal Frontiers in Microbiology in April 2020 discusses the most attractive approaches among the broad spectrum of experimental and theoretical strategies being worked on to counter the COVID-19 pandemic.

24 Apr 2020

SARS-CoV-2 targets specific cells in the lung, nasal passage, and intestine

Now, the researchers from the Massachusetts Institute of Technology (MIT) have identified specific types of cells that are targets of the SARS-CoV-2 that causes the COVID-19 pandemic. The findings of the study published in the journal Cell may help in developing novel therapeutics to combat the deadly viral infection.

23 Apr 2020

Poor quality testing could increase number of COVID-19 infections

A new study published in the preprint open-access journal medRxiv in April 2020 assesses the value of untargeted testing for infection or immunity in COVID-19 vs. high-quality targeted testing in keeping down the number of infections while slowly relaxing lockdown measures.

23 Apr 2020

Low-cost, portable detector takes about 30 minutes to identify pathogens

Most viral test kits rely on labor- and time-intensive laboratory preparation and analysis techniques; for example, tests for the novel coronavirus can take days to detect the virus from nasal swabs.

23 Apr 2020

Novel method may enable decentralized facilities to deliver faster COVID-19 test services

The COVID-19 pandemic has resulted in over 2.5 million confirmed cases worldwide and nearly over 170,000 deaths as of April 21 according to the World Health Organization.

23 Apr 2020

Study identifies key nose cells as likely COVID-19 virus entry points

Two specific cell types in the nose have been identified as likely initial infection points for COVID-19 coronavirus. Scientists discovered that goblet and ciliated cells in the nose have high levels of the entry proteins that the COVID-19 virus uses to get into our cells.

23 Apr 2020

Breakthrough discovery in HIV research opens path to new, better therapies

New research on the human immunodeficiency virus (HIV) structure has revealed a promising novel drug target for treating it.

23 Apr 2020

UMB and UMD fund cross-campus research projects

The University of Maryland, Baltimore (UMB) and the University of Maryland, College Park (UMD) are funding new cross-campus research projects as part of a new joint program that seeks to solve big health care challenges through joint research that draws on the institutions world leading expertise in medicine and artificial intelligence.

23 Apr 2020