RNA Sequencing News and Research

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Aberrant levels of three microRNAs may impair healing in venous ulcers, study shows

The study, which includes the first resource detailing the role of microRNAs in the wound-repair process, shows that aberrant levels of a trio of microRNAs may impair healing in venous ulcers.

9 Aug 2022

Study reveals the intertumoral heterogeneity of METex14 skipping positive NSCLCs

A study presented today at the IASLC World Conference on Lung Cancer 2022 in Vienna disclosed the clinical-relevant intertumoral heterogeneity of non-small cell lung cancer (NSCLC) driven by MET exon 14 skipping.

8 Aug 2022

Baboons at Amboseli offer clues to the costs of the hybridization, study says

New genetic analyses of wild baboons in southern Kenya reveals that most of them carry traces of hybridization in their DNA. As a result of interbreeding, about a third of their genetic makeup consists of genes from another, closely-related species.

5 Aug 2022

Heart failure arises from mutations in distinct genes, study finds

Heart failure is a common and devastating disorder for which there is no cure. Many cardiomyopathies -;conditions that make it difficult for the heart to pump blood such as dilated cardiomyopathy (DCM) and arrhythmogenic cardiomyopathy (ACM) -; can lead to heart failure, but treatments for patients with heart failure do not take these distinct conditions into account.

5 Aug 2022

Discovery could prevent insulin resistance and have significant benefits for people with type 2 diabetes

In a potential game changer for patients with type 2 diabetes, a team of researchers at the Diabetes, Obesity, and Metabolism Institute (DOMI) at the Icahn School of Medicine at Mount Sinai has identified a therapeutic target for the preservation and regeneration of beta cells (β cells)-;cells in the pancreas that produce and distribute insulin.

4 Aug 2022

Less efficient replication of ancestral SARS-CoV-2 in primary nasal epithelium of children

A new study revealed that the replication of the ancestral strain of SARS-CoV-2 is less efficient in nasal epithelial cells (NECs) of children.

3 Aug 2022

Study reveals how barrier cells that line the intestines send messages to patrolling T cells

Cells in the gut send secret messages to the immune system. Thanks to new research from La Jolla Institute for Immunology (LJI) scientists, we can finally get a look at what they're saying.

29 Jul 2022

Researchers discover cell signaling pathway responsible for the development of esophageal cancers

Of the roughly 20,000 people in the U.S. diagnosed with esophageal cancer this year, just 4,000 are likely to still be alive in 2027.

28 Jul 2022

Study identifies risks in the use of CRISPR therapeutics

The researchers caution: "The CRISPR genome editing method is very effective, but not always safe. Sometimes cleaved chromosomes do not recover and genomic stability is compromised - which in the long run might promote cancer."

25 Jul 2022

Using genome editing to expand the possibilities of entomological research

Genome sequencing, where scientists use laboratory methods to determine a specific organism's genetic makeup, is becoming a common practice in insect research.

22 Jul 2022

NIH grant awarded to Marshall researcher for studying genetic mechanisms of cocaine addiction

Price E. Dickson, Ph.D., an assistant professor of biomedical sciences at the Marshall University Joan C. Edwards School of Medicine, has received a $407,000 grant from the National Institutes of Health to study the genetic and genomic mechanisms driving the relationship between social reward and cocaine addiction.

22 Jul 2022

Brown researchers develop an advanced way to isolate single cells from complex tissues

In cancer research, it all comes down to a single cell. Over the last decade, cancer researchers have homed in on the fact that an individual cell from a tumor can be used to perform molecular analyses that reveal important clues about how the cancer developed, how it spreads and how it may be targeted.

14 Jul 2022

Study sheds light on cell type-specific biomarkers of melanoma

A new UC Davis-led study sheds light on cell type-specific biomarkers, or signs, of melanoma. The research was recently published in the Journal of Investigative Dermatology.

10 Jul 2022

Revolutionary technology identifies molecular alterations in failing hearts at single-cell resolution

Imagine, if scientists had a map of the heart, so granular in its accuracy that it even profiled details of the heart at the cellular level.

8 Jul 2022

Intrahost genetic diversity and evolution of the SARS-CoV-2 B.1.517 lineage during chronic infection of an immunocompromised individual

Researchers investigated the intrahost evolution and genetic diversity of the SARS-CoV-2 B.1.517 variant in an immunosuppressed person with chronic COVID-19.

6 Jul 2022

RNA Sequencing News and Research

Aberrant levels of three microRNAs may impair healing in venous ulcers, study shows

Study reveals the intertumoral heterogeneity of METex14 skipping positive NSCLCs

Baboons at Amboseli offer clues to the costs of the hybridization, study says

Heart failure arises from mutations in distinct genes, study finds

Discovery could prevent insulin resistance and have significant benefits for people with type 2 diabetes

Less efficient replication of ancestral SARS-CoV-2 in primary nasal epithelium of children

Study reveals how barrier cells that line the intestines send messages to patrolling T cells

Researchers discover cell signaling pathway responsible for the development of esophageal cancers

Study identifies risks in the use of CRISPR therapeutics

Using genome editing to expand the possibilities of entomological research

NIH grant awarded to Marshall researcher for studying genetic mechanisms of cocaine addiction

Brown researchers develop an advanced way to isolate single cells from complex tissues

Study sheds light on cell type-specific biomarkers of melanoma

Revolutionary technology identifies molecular alterations in failing hearts at single-cell resolution

Intrahost genetic diversity and evolution of the SARS-CoV-2 B.1.517 lineage during chronic infection of an immunocompromised individual

Deep RNA sequencing with molecular dynamic simulations can detect neutralizing antibodies elicited by COVID-19 patients

New technique offers higher-precision scRNA-seq data than current technologies

Genome analysis of alphacoronavirus and betacoronavirus species from South Korean bats

Molecular tumor profiling in pediatric cancer patients significantly impacts clinical care

Researchers discover two important novel aspects of APOE4 gene in Alzheimer's patients

Sequencing & Genomics: Elevating Science and Healthcare eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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