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Intestinal cells can change specializations during their lives, finds study

Intestinal cells can change specializations during their lives. The BMP signaling pathway – an important communication mechanism between cells – appears to be the driver of these changes.

1 Mar 2022

Novel coronavirus identified in Swedish bank voles

Researchers recently discovered a new coronavirus, named Grimso virus, in Swedish bank voles, using samples collected between 2015 and 2017.

1 Mar 2022

LJI researchers discover new genes in CD4+ "helper" T cell subsets

T cells play important roles in helping to fight infections and cancers-;and they can also drive autoimmune diseases. Now researchers at La Jolla Institute for Immunology (LJI) have discovered new genes in CD4+ "helper" T cell subset that are linked to risk of autoimmune diseases.

25 Feb 2022

Crucial regulator of malaria parasite transmission identified

Malaria remains one of the biggest global public health challenges. It kills a young child every two minutes, more than any other infectious disease.

25 Feb 2022

Mapping cells to understand vascular disease

In this interview, we speak to Dr. Ethan Winkler and Dr. Tomasz Nowakowski about their latest research which illustrated the interplay between vascular and immune cells that contributes to brain hemorrhage.

25 Feb 2022

MAIT cells exercise complex functions and may be targets for future immunotherapies and vaccines

A Stony Brook University physician-scientist has identified that mucosal-associated invariant T (MAIT) cells, an unconventional form of immune cell, exercise several complex roles during healthy and disease states.

24 Feb 2022

Genetic analysis reveals eosinophilic colitis as a unique disease

A condition called eosinophilic colitis is distinct from other, similar eosinophilic gastrointestinal diseases and inflammatory bowel disease, according to a genetic analysis published in Gastroenterology.

24 Feb 2022

Lung microbiome alterations and secondary-infections in lethal COVID-19

Researchers examined how an interplay of host and microbial factors weakened immunity leading to secondary infections in COVID-19-infected individuals.

22 Feb 2022

Scientists use entire human GI tracts to shed light on cellular functions

If you get nervous, you might feel it in your gut. If you eat chili, your gut might revolt, but your friend can eat anything and feel great. You can pop ibuprofen like candy with no ill effects, but your friend's belly might bleed and she might get no pain relief.

21 Feb 2022

Response of peripheral immune cells to ex vivo SARS-CoV-2 exposure compared to SARS-CoV

Researchers characterized the responses of the PBMCs at the individual cell and cell type levels against SARS-CoV-2 and SARS-CoV ex vivo.

18 Feb 2022

New mutation may define a high-risk subtype of pediatric acute myeloid leukemia

A new mutation was identified in 9 percent of relapsed cases of pediatric acute myeloid leukemia (AML) that may define a new subtype of the disease.

17 Feb 2022

Researchers discover a new and unconventional nuclear function for cancer microRNA

microRNAs (miRNA), non-coding RNA molecules, are widely known for regulating mRNA stability and translation. miR-10b has been increasingly implicated in the pathogenesis of gliomas, cancers of the brain.

16 Feb 2022

New cell model for Alzheimer's disease could be useful in early diagnosis and testing of new therapies

Researchers at the University of Eastern Finland have developed and characterized a new cell model for Alzheimer's disease that has wide utility for research and could prove useful in early diagnosis and testing of new therapies.

16 Feb 2022

Researchers create a comprehensive atlas of cerebrovascular cell types

While neurons and glial cells are by far the most numerous cells in the brain, many other types of cells play important roles. Among those are cerebrovascular cells, which form the blood vessels that deliver oxygen and other nutrients to the brain.

15 Feb 2022

New DisCo method allows scRNA-seq to efficiently process samples with fewer cells

Single-cell RNA sequencing, or "scRNA-seq" for short, is a technique that allows scientists to study the expression of genes in an individual cell within a mixed population – which is virtually how all cells exist in the body's tissues.

15 Feb 2022

Single-cell sequencing provides detailed insight into early SARS-CoV-2 infection in the lungs

What is going on at the single-cell level in the first days of SARS-CoV-2 infection in the lungs?

9 Feb 2022

Antibody drug improves survival rates in canine prostate cancer model

Dogs are proving to be a far better scientific model for study of prostate cancer than mice, the typical animal used in the lab for this type of research.

8 Feb 2022

Maternal metabolic syndrome can switch on imprinted gene associated with NAFLD in offspring

New research from North Carolina State University has found that an imprinted gene associated with development of non-alcoholic fatty liver disease (NAFLD) is switched on in mice who nurse from mothers with metabolic syndrome, even when those mice are not biologically related.

7 Feb 2022

Innate and adaptive immune responses to SARS-CoV-2 in convalescent children and adults

In a new study, researchers explored the systemic immune responses during the acute and convalescent phases of SARS-CoV-2 in children and adults with the same disease severity.

3 Feb 2022

Study describes the first three days of SARS-CoV-2 infection in an ALI model of proximal airway epithelium

Researchers evaluated the initial three days of SARS-CoV-2 infection via scRNAseq dataset in humanized in vitro model.

3 Feb 2022

RNA Sequencing News and Research

Intestinal cells can change specializations during their lives, finds study

Novel coronavirus identified in Swedish bank voles

LJI researchers discover new genes in CD4+ "helper" T cell subsets

Crucial regulator of malaria parasite transmission identified

Mapping cells to understand vascular disease

MAIT cells exercise complex functions and may be targets for future immunotherapies and vaccines

Genetic analysis reveals eosinophilic colitis as a unique disease

Lung microbiome alterations and secondary-infections in lethal COVID-19

Scientists use entire human GI tracts to shed light on cellular functions

Response of peripheral immune cells to ex vivo SARS-CoV-2 exposure compared to SARS-CoV

New mutation may define a high-risk subtype of pediatric acute myeloid leukemia

Researchers discover a new and unconventional nuclear function for cancer microRNA

New cell model for Alzheimer's disease could be useful in early diagnosis and testing of new therapies

Researchers create a comprehensive atlas of cerebrovascular cell types

New DisCo method allows scRNA-seq to efficiently process samples with fewer cells

Single-cell sequencing provides detailed insight into early SARS-CoV-2 infection in the lungs

Antibody drug improves survival rates in canine prostate cancer model

Maternal metabolic syndrome can switch on imprinted gene associated with NAFLD in offspring

Innate and adaptive immune responses to SARS-CoV-2 in convalescent children and adults

Study describes the first three days of SARS-CoV-2 infection in an ALI model of proximal airway epithelium

Sequencing & Genomics: Elevating Science and Healthcare eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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