RNA Sequencing News and Research

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RNA sequencing analysis feasible for diagnosis of molecular subtypes in pediatric B-ALL

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, representing more than 30% of all pediatric cases.

29 Jan 2024

New workflow identifies shared cancer targets, advancing immunotherapy

Researchers developed the Splicing Neo Antigen Finder (SNAF) workflow, integrating deep learning to identify shared immunogenic neoantigens in cancers, offering new targets for cancer immunotherapy, particularly in melanoma and ovarian cancer.

23 Jan 2024

Discovery of toxic and protective short RNAs associated with Alzheimer's disease and superior memory capacity

Researchers explored how Death Induced by Survival gene Elimination through the analysis of RNA-induced silencing complex-bound short RNAs in Alzheimer's disease models influences neuronal survival and correlates with neurotoxicity in AD.

22 Jan 2024

Prior mycobacterium exposure remodels immune cells, impacting tuberculosis defense

Tuberculosis, caused by the bacterium Mycobacterium tuberculosis (Mtb) kills upwards of 1.6 million people a year, making it one of the leading causes of death by an infectious agent worldwide-;and that number is only growing larger.

18 Jan 2024

Immune dysregulation in long COVID patients uncovered in new study

Sstudy reveals significant immune changes in long COVID patients, including altered T cell responses and systemic inflammation, using advanced 'omics' and serological assays.

14 Jan 2024

Stromal cells may be useful in assessing prostate tumors' potential to spread

Non-cancerous cells called stromal cells, which are found in and around prostate tumors, may be useful in assessing these tumors' potential to spread, and may even be targets for future prostate cancer treatments, according to a study led by researchers at Weill Cornell Medicine.

12 Jan 2024

Big data analysis paves way for personalized ovarian cancer treatment

A recent study led by Hidenori Machino at the RIKEN Center for Advanced Intelligence Project (AIP) and the National Cancer Center Research Institute in Japan used a big data multi-omics analysis to examine changes in gene expression as cells from human fallopian tubes become cancerous.

11 Jan 2024

Study identifies distinct CD4+ T cell changes in various autoimmune diseases

Much like ripples on the water can betray powerful currents below the surface, small changes in our bodies can sometimes be an indicator of a serious condition.

11 Jan 2024

Largest genetic study of gestational diabetes discovers nine novel genetic regions linked to severe and common pregnancy complication

Researchers investigated the genetic underpinnings of Gestational Diabetes Mellitus (GDM) and its relationship with Type 2 Diabetes (T2D) through a genome-wide association study ((GWAS), identifying distinct and shared genetic factors.

9 Jan 2024

£30M clinical study will enhance the understanding of NASH cirrhosis

The most extensive clinical study into liver cirrhosis ever conducted worldwide has been announced by Newcastle University, University of Edinburgh and leading research-driven global biopharmaceutical company, Boehringer Ingelheim.

8 Jan 2024

Study finds Epstein-Barr virus T-cells prevalent in early multiple sclerosis

A study led by UTHealth Houston reveals that T-cells specific for Epstein-Barr virus-infected cells are highly present in the cerebrospinal fluid of people with early-stage multiple sclerosis, suggesting a link between EBV and the disease.

8 Jan 2024

Gut microbiota: the new frontier in Alzheimer’s disease research and therapy

The current evidence of the role of gut microbiota in Alzheimer’s disease (AD) pathogenesis.

8 Jan 2024

Revolutionary study reveals Lactobacillus acidophilus could ward off liver cancer linked to fatty liver disease

Probiotic supplementation with Lactobacillus acidophilus could help prevent non-alcoholic fatty liver disease.

8 Jan 2024

Unlocking the power of diet: How miRNAs influence health and disease

The role of dietary microRNAs (miRNAs) in health and disease.

5 Jan 2024

High-resolution map of the neuroblastoma immune landscape points to new target for immunotherapy

A detailed 'atlas' of neuroblastoma tumors points to a new target for immunotherapy. Scientists from the Princess Máxima Center for Pediatric Oncology in the Netherlands mapped this childhood tumor at the level of individual cancer and immune cells.

4 Jan 2024

Shedding new light on the hidden organization of the cytoplasm

Back in 2018, the lab of Christine Mayr, MD, PhD, at Memorial Sloan Kettering Cancer Center (MSK) introduced the world to a key cellular component that had been hiding in plain sight.

21 Dec 2023

Hederasaponin C may be a protective measure and novel therapeutic strategy for diabetic nephropathy

Announcing a new publication for Acta Materia Medica journal. There is great demand for the development of novel efficient therapeutic strategies or preventative measures to alleviate the life-threatening complications of type 2 diabetes.

21 Dec 2023

Single-cell RNA sequencing generates comprehensive atlas of zebrafish development

Researchers at the National Institutes of Health have published an atlas of zebrafish development, detailing the gene expression programs that are activated within nearly every cell type during the first five days of development, a period in which embryos mature from a single cell into distinct cell types.

18 Dec 2023

RNA-seq analysis reveals key factors in intervertebral disc degeneration

In a rapid communication published in the journal Genes & Diseases, researchers from Chongqing Medical University and Yongchuan Traditional Chinese Medicine Hospital of Chongqing have unveiled crucial insights into the factors that might influence Intervertebral Disc Degeneration (IDD).

15 Dec 2023

Waseda researchers unravel secrets of building better brain organoids with blood vessels

Researchers at Waseda University led by Assistant Professor Kosuke Kataoka, have uncovered crucial insights into brain organoids’ development.

15 Dec 2023

RNA Sequencing News and Research

RNA sequencing analysis feasible for diagnosis of molecular subtypes in pediatric B-ALL

New workflow identifies shared cancer targets, advancing immunotherapy

Discovery of toxic and protective short RNAs associated with Alzheimer's disease and superior memory capacity

Prior mycobacterium exposure remodels immune cells, impacting tuberculosis defense

Immune dysregulation in long COVID patients uncovered in new study

Stromal cells may be useful in assessing prostate tumors' potential to spread

Big data analysis paves way for personalized ovarian cancer treatment

Study identifies distinct CD4+ T cell changes in various autoimmune diseases

Largest genetic study of gestational diabetes discovers nine novel genetic regions linked to severe and common pregnancy complication

£30M clinical study will enhance the understanding of NASH cirrhosis

Study finds Epstein-Barr virus T-cells prevalent in early multiple sclerosis

Gut microbiota: the new frontier in Alzheimer’s disease research and therapy

Revolutionary study reveals Lactobacillus acidophilus could ward off liver cancer linked to fatty liver disease

Unlocking the power of diet: How miRNAs influence health and disease

High-resolution map of the neuroblastoma immune landscape points to new target for immunotherapy

Shedding new light on the hidden organization of the cytoplasm

Hederasaponin C may be a protective measure and novel therapeutic strategy for diabetic nephropathy

Single-cell RNA sequencing generates comprehensive atlas of zebrafish development

RNA-seq analysis reveals key factors in intervertebral disc degeneration

Waseda researchers unravel secrets of building better brain organoids with blood vessels

Sequencing & Genomics: Elevating Science and Healthcare eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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