Radionuclide News and Research

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Nanotubes offer new approach to cancer radiotherapy

Radioactive elements, or radionuclides, are well-established anticancer agents whose main limitation is that they kill healthy cells almost as easily as they do tumors. But because nanoparticles can be targeted to tumors, researchers have seized on the idea of using nanoparticles to deliver radionuclides to tumors, thus sparing healthy tissues from radiation-induced damage.

22 Aug 2007

PET plus CT - best test for ovarian cancer

An advanced molecular imaging technique influenced the management of women with ovarian cancer, detected more sites of disease and identified women whose disease was likely to progress, according to an Australian study released during the 54th Annual Meeting of SNM, the world's largest society for molecular imaging and nuclear medicine professionals.

5 Jun 2007

FDG-PET imaging predicts lung cancer patients' response to chemotherapy

An earlier indication of whether chemotherapy benefits non-small cell lung cancer patients, provided by positron emission tomography (PET) imaging, can guide doctors in offering them better care, according to researchers in the May Journal of Nuclear Medicine.

10 May 2007

Researchers wake up viruses inside tumors to image and then destroy cancers

They say this strategy could offer a novel way of treating many cancers associated with Epstein-Barr, including at least four different types of lymphoma and nasopharyngeal and gastric cancers.

1 Mar 2007

In vivo tumor targeting and radionuclide imaging with self-assembled nanoparticles

In an attempt to determine what factors make one nanoparticle better than another at targeting tumors, a team of investigators in Korea have conducted a systematic tumor-targeting study of a variety of self-assembling nanoparticles.

18 Dec 2006

Targeted tumor therapy has paramount consequences for future expansion of nuclear medicine

Targeted tumor therapy lobs toxic payloads directly into tumors to destroy cancer cells while leaving normal cells unharmed.

20 Oct 2006

Permanent renal parenchymal defects after febrile UTI are closely associated with vesicoureteric reflux

This study from Italy investigated the association of vesicoureteral reflux (VUR) and renal scarring.

5 Sep 2006

Radioactive treatment can set off security alarms

According to a new case report patients receiving radioactive isotopes should be warned that they may trigger radiation alarms for several weeks after the treatment has been completed.

7 Aug 2006

Patients receiving treatment with radioisotopes may trigger security alarms

Patients receiving treatment with radioisotopes should be warned that they may trigger radiation alarms, say doctors in this week's British Medical Journal.

3 Aug 2006

The solitary pulmonary nodule - malignant or benign?

A new study published in the journal Respiration shows good overall diagnostic accuracy of technetium-99m (99mTc)-depreotide single photon emission computed tomography (SPECT) in separating malignant from benign solitary pulmonary nodules (SPNs) of indeterminate origin.

19 Jun 2006

Radionuclide therapy with chemotherapy effective in treating prostate cancer

A new treatment for prostate cancer may provide a distinct advantage over other conventional protocols and induce actual regression of the disease - not just relief from bone pain or a limited control of the disease.

9 Jun 2006

Mental stress induced ischemia more common than thought

Even when heart disease patients can pass stress tests done on a treadmill or with chemical stressors after treatment, their hearts may still suffer silent ischemia during mental stress, according to a new study in the Mar. 7, 2006, issue of the Journal of the American College of Cardiology.

13 Mar 2006

Anxiety restricts blood flow in some patients

The fear of public speaking might cause some people to do more than just break out in a cold sweat and battle stomach-churning butterflies - it could prove to have consequences for their heart health.

13 Mar 2006

Prevalence and patterns of physiologic muscle uptake detected with whole-body PET

Muscle activity - from turning a page in a book to shoveling snow - impacts positron emission tomography results, says study in journal of nuclear medicine technology.

9 Mar 2006

Chernobyl: The True Scale of the Accident

A total of up to four thousand people could eventually die of radiation exposure from the Chernobyl nuclear power plant (NPP) accident nearly 20 years ago, an international team of more than 100 scientists has concluded.

5 Sep 2005

Positron emission tomography (PET) imaging can identify effectiveness of chemotherapy early in high-risk breast cancer patients

The effectiveness of chemotherapy in patients with advanced breast cancer can be evaluated earlier by using 18F-FDG positron emission tomography (PET) imaging over other conventional imaging procedures, according to an article in the July issue of the Society of Nuclear Medicine's Journal of Nuclear Medicine.

26 Jul 2005

Computer program that enhances the diagnostic accuracy of positron emission tomography (PET)

German scientists developed a computer program that enhances the diagnostic accuracy of positron emission tomography (PET) scans with Alzheimer's patients, opening the door for earlier treatment of this progressive brain disorder. Details of their findings were provided at the Society of Nuclear Medicine's 52nd Annual Meeting in Toronto.

20 Jun 2005

Cytogen Corporation and Dowpharma collaborate to create a targeted oncology product designed to treat prostate and other cancers

Under the agreement, Dowpharma's proprietary MeO-DOTA bifunctional chelant technology will be used to radiolabel Cytogen's prostate-specific membrane antigen (PSMA) antibody with a therapeutic radionuclide. PSMA is a protein highly expressed on the surface of prostate cancer cells and the neovasculature of many solid tumors.

10 May 2005

Data suggests potential role of Quadramet in conjunction with chemotherapy for the treatment of acute myeloid leukemia

Cytogen Corporation today announced the presentation of new data relating to its lead therapeutic product Quadramet (samarium Sm-153 lexidronam injection) during the 36th Congress of the International Society of Pediatric Oncology (SIOP).

20 Sep 2004