Red Blood Cells News and Research

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St. Jude researchers discover NLRP12 as a direct bridge from hemolysis to inflammatory disease

Infections and other diseases can cause red blood cells to rupture, releasing the oxygen-binding molecule hemoglobin, which breaks down into heme.

1 Jun 2023

Treatment with luspatercept improves red blood cell counts in patients with myelodysplastic syndromes

Treatment with luspatercept improved red blood cell counts and erythroid responses compared to treatment with epoetin alfa in patients with myelodysplastic syndromes (MDS), allowing the majority to no longer require regular blood transfusions.

26 May 2023

Targeting the hemoglobin problem in sickle cell disease using a new drug

A class of drugs used for their ability to stop tumor cells from dividing is now under study for their potential to reduce the pain and damage caused by sickle cell disease, investigators report.

11 May 2023

New approach addresses the challenge of directly connecting genetic variants to human traits, health

A major challenge in human genetics is understanding which parts of the genome drive specific traits or contribute to disease risk. This challenge is even greater for genetic variants found in the 98% of the genome that does not encode proteins.

5 May 2023

Four important signs that signal increased risk of early-onset colorectal cancer identified

Researchers at Washington University School of Medicine in St. Louis have identified four important signs and symptoms that signal an elevated risk of early-onset colorectal cancer.

5 May 2023

Powerful two-photon microscopy for imaging fast biological processes

Two-photon microscopy (TPM) has revolutionized the field of biology by enabling researchers to observe complex biological processes in living tissues at high resolution.

4 May 2023

A dimensional reduction strategy for enhanced cryopreservation of red blood cells

Small amounts of nanometer-thin metal-organic layers efficiently protect red blood cells during freezing and thawing, as a team of researchers writing in the journal Angewandte Chemie has discovered. The nanolayers, made from metal-organic frameworks based on the metal hafnium, prevent ice crystal formation at very low concentrations. This effective novel cryoprotection mode could be used to develop new and more efficient cryoprotectants for the biosciences.

29 Apr 2023

Laser speckle-based noncontact technique enables imaging the vasculature of a beating heart

In the majority of cases, graft failure after heart transplantation is attributable to abnormalities like severe coronary artery disease.

25 Apr 2023

Immune cells in the duodenum may be responsible for iron absorption problems, study suggests

Approximately one to two milligrams of the trace element must be supplied daily through food and finally absorbed in the duodenum for a balanced iron metabolism.

20 Apr 2023

Precise genome editing approach can correct mutation that causes sickle cell disease

Scientists at St. Jude Children’s Research Hospital and the Broad Institute of MIT and Harvard showed how prime editing can correct the mutation that causes sickle cell disease in a potentially curative approach.

18 Apr 2023

Combination treatment could improve stem cell transplantation process for multiple myeloma patients

The standard treatment for patients with multiple myeloma often includes stem cell transplantation in which the patient's own stem cells are harvested and stored while the patient receives intensive chemotherapy to kill the cancer.

17 Apr 2023

Study compared the milk composition and nutritional status of omnivore milk donors and vegetarian lactating mothers

Researchers compared the nutritional status composition of omnivorous diet-abiding milk donors and vegetarian/vegan lactating women.

14 Apr 2023

Genomic study reveals Babesia duncani's pathogenicity and virulence

'Tis the season for hiking now that spring has arrived and temperatures are on the upswing. But with hikes come insect bites and on the increase in North America is babesiosis, a malaria-like disease spread especially between May and October by a tick.

13 Apr 2023

Study explains why leukemia survivors experience negative effects on blood formation decades later

Contrary to previous belief, stem cells, from which all new blood cells are formed, remain in bone marrow in the blood cancer type acute lymphocytic leukemia.

5 Apr 2023

Key molecular pathway for organ damage in COVID patients discovered

Even after three years since the emergence of COVID-19, much remains unknown about how it causes severe disease, including the widespread organ damage beyond just the lungs.

5 Apr 2023

Fatigue is common among older adults, and it has many possible causes

Nothing prepared Linda C. Johnson of Indianapolis for the fatigue that descended on her after a diagnosis of stage 4 lung cancer in early 2020.

4 Apr 2023

Red blood cell hitch-hiking facilitates SARS-CoV-2 multi-organ spread

Researchers assessed the infectious capacity of severe acute respiratory syndrome coronavirus 2 in plasma and red blood cells.

3 Apr 2023

Losing weight with lifestyle changes may reduce cardiovascular risk- even if some weight is regained

Losing weight with lifestyle changes in an intensive behavioral weight loss program was associated with a decrease in risk factors for cardiovascular disease and Type 2 diabetes for at least five years -; even if some weight was regained, according to a systematic review of research, published today in Circulation: Cardiovascular Quality and Outcomes, a peer-reviewed American Heart Association journal.

28 Mar 2023

Mercury and urinary arsenobetaine in blood are strong biomarkers for seafood consumption among pregnant women

Mercury content in RBCs and arsenobetaine in urine could be considered seafood consumption biomarkers during pregnancy.

10 Mar 2023

Detection and targeting of splicing deregulation reveal a potential strategy for pAML therapy

Pediatric acute myeloid leukemia or pAML is a childhood blood cancer, one that has proved confounding to clinicians and researchers, with a high relapse rate and relatively few identified genetic mutations (compared to the adult version) that might explain its cause.

8 Mar 2023