Remdesivir News and Research

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Convalescent plasma therapy improves outcomes in majority of COVID-19 patients

First peer-reviewed publication on US trial results from Houston Methodist published in The American Journal of Pathology

3 Jun 2020

A cytokine pattern that predicts adverse outcomes in COVID-19

A new study published on the preprint server medRxiv in May 2020 reports the discovery of a predictive pattern of cytokines in COVID-19 infection that could guide clinical management if validated.

2 Jun 2020

Crucial ingredient from University of Kansas included in authorized COVID-19 drug

When the Food and Drug Administration issued an emergency-use authorization for the investigational pharmaceutical remdesivir to treat COVID-19 on May 1, in part it was due to pioneering work performed by pharmaceutical chemists at the University of Kansas School of Pharmacy in 1990.

1 Jun 2020

5-day Remdesivir dose works as well as the 10-day dose in COVID-19, study finds

With more than 5.8 million people infected with the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the search is on for an effective SARS-CoV-2 vaccine or drug to treat COVID-19 disease.

28 May 2020

Researchers grow lung organoids from stem cells for Sars-Cov-2 research

A Bochum-based team intends to use organoids from stem cells to study the progression of Sars-CoV-2 infection and to identify antiviral substances.

28 May 2020

Canadian study of COVID-19 patients admitted to ICUs finds lower overall mortality

A Canadian case series of all patients with COVID-19 admitted to six intensive care units (ICUs) in Metro Vancouver found patient outcomes were substantially better than reported in other jurisdictions. The paper is published in CMAJ.

27 May 2020

Emerging antiviral may turn the tide for COVID-19 pandemic

Scientists everywhere are working overtime to develop treatments for COVID-19, the disease caused by the novel coronavirus SARS-CoV-2.

27 May 2020

Investigational antiviral superior to standard of care for treating COVID-19 patients

The investigational antiviral remdesivir is superior to the standard of care for the treatment of COVID-19, according to a report published today in The New England Journal of Medicine.

27 May 2020

Montefiore and Einstein evaluate a new drug combination to fight COVID-19

Montefiore Health System Albert Einstein College of Medicine have begun the next stage of the Adaptive COVID-19 Treatment Trial (ACTT), to evaluate treatment options for people hospitalized with severe COVID-19 infection.

26 May 2020

Zero benefit of Hydroxychloroquine or Chloroquine in COVID-19, says extensive study

The purported "game-changer" anti-malarial drug Hydroxychloroquine, which was claimed to be effective in preventing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and also helping better outcomes in COVID-19 patients, seems to have failed in clinical trials.

25 May 2020

Using Qigong to manage COVID-19 in older adults

A recent study published in The American Journal of Geriatric Psychiatry in May 2020 reports on the possible usefulness of the integrative practice called Qigong to prevent and manage COVID-19 in older adults.

25 May 2020

Children with COVID-19 presenting with sudden severe lung disease

Even as the COVID-19 pandemic continues to seek out new victims, puzzling new presentations are further confusing the situation. A new study published online in The Lancet Rheumatology in May 2020 reports a case of severe COVID-19 in a child who rapidly developed acute respiratory distress symptoms without prior respiratory symptoms. This case should alert clinicians to consider this diagnosis in children as well.

24 May 2020

Lifesaving innovation for COVID-19 will increase the already existing racial inequalities

As is the case with most fatal diseases, coronavirus disease (COVID-19) is already taking a disproportionate toll on black Americans and other disadvantaged minorities.

20 May 2020

Taking blood pressure medicines as usual is important during COVID-19 pandemic

Keeping your blood pressure under control is especially important during the COVID-19 pandemic – so keep taking your blood pressure medicines!

20 May 2020

Three FDA-approved drugs can block the replication of COVID-19 virus

Three drugs that are already approved by the Food and Drug Administration (FDA) or other international agencies can block the production of the novel coronavirus that causes COVID-19 in human cells, according to computational and pharmaceutical studies performed by UT Southwestern scientists.

19 May 2020

ECMO machine can be useful for treating critically ill COVID-19 patients

When COVID-19 patients are critically ill, the biggest threat to their lives is lung dysfunction. If their lungs don't work, their blood can't circulate enough oxygen to the brain, the liver and other organs.

18 May 2020

Scant clinical research for pregnant and lactating women with COVID-19

Pregnant and breastfeeding women have been excluded from clinical trials of drugs to treat COVID-19, and as result, there is no safety data to inform clinical decisions. Such drugs include remdesivir according to a new article in the peer-reviewed journal Breastfeeding Medicine.

18 May 2020