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Positive results from Synta's Ganetespib Phase 2 trial on HER2-positive and triple negative mBC

Synta Pharmaceuticals Corp. - Ganetespib, a potent, second generation Hsp90 inhibitor, has demonstrated clinical activity in heavily pre-treated patients with HER2-positive and triple negative metastatic breast cancer according to Phase 2 clinical trial results presented by researchers from Memorial Sloan-Kettering Cancer Center at the San Antonio Breast Cancer Symposium.

9 Dec 2011

Young football players may be at higher risk for stroke

Young football players may be at higher risk for stroke, according to a new study released in Journal of Child Neurology (JCN), published by SAGE.

9 Dec 2011

Combination of MEK inhibitors and nilotinib can overcome CML resistance to targeted drug

Cancer Research UK-funded scientists at The Institute of Cancer Research (ICR) have revealed a technique to kill chronic myeloid leukaemia (CML) cells that have stopped responding to a targeted drug, according to research published in Cancer Cell today.

9 Dec 2011

Girls suffer more frequently from chronic pain than boys

Children who suffer from persistent or recurring chronic pain may miss school, withdraw from social activities, and are at risk of developing internalizing symptoms such as anxiety, in response to their pain. In the first comprehensive review of chronic pain in children and adolescents in 20 years, a group of researchers found that more children now are suffering from chronic pain and that girls suffer more frequently from chronic pain than boys.

9 Dec 2011

Roundup: Ohio lawmakers consider abortion bill; Aetna sues Mich. Blues

An Ohio lawmaker on Wednesday touted the importance of the fetal heartbeat as an indicator of life as he urged a legislative panel to support a bill that would impose the nation's most stringent abortion limit. The measure would outlaw abortions at the first detectable fetal heartbeat. That's sometimes as early as six weeks into pregnancy.

9 Dec 2011

Scientists uncover three new locations for Crohn's Disease genes

Three new locations for Crohn's Disease genes have been uncovered by scientists at UCL using a novel gene mapping approach.

9 Dec 2011

Nurses report symptoms of burnout, job dissatisfaction

Nurses working in hospitals around the world are reporting they are burned out and dissatisfied with their jobs, reported researchers at the University of Pennsylvania School of Nursing's Center for Health Outcomes and Policy Research in a study of 100,000 nurses in nine countries.

9 Dec 2011

ACEP Emergency Ultrasound Guidelines receive AIUM recognition

In keeping with the American Institute of Ultrasound in Medicine's (AIUM) overarching mission of advancing the safe and effective use of ultrasound in medicine through education, research and development of guidelines, the AIUM recognizes the American College of Emergency Physicians (ACEP) Policy Statement Emergency Ultrasound Guidelines as meeting the qualifications for performing ultrasound in the emergency setting.

9 Dec 2011

Forbes interviews Sarah Brown about her work in maternal, child health advocacy

Sarah Brown, international advocate for global maternal and newborn health and wife of former British Prime Minister Gordon Brown, answers questions about her work from Forbes contributor Rahim Kanani in this interview excerpt.

9 Dec 2011

Viewpoints: Politics overtakes Plan B; Gingrich's entitlement plans; Cheeseburgers and death

Once again, the politics of birth control have trumped science and sound public policy. On Wednesday, the Obama administration overruled a carefully reasoned decision by the Food and Drug Administration to make the so-called morning-after pill available without prescription to adolescent girls below the age of 17.

9 Dec 2011

Scientists discover mechanism that controls 'fat switch' in the body

Scientists at Warwick Medical School have made an important discovery about the mechanism controlling the body's 'fat switch', shedding new light on our understanding of how proteins regulate appetite control and insulin secretion.

9 Dec 2011

Toxins in Danish mushroom are effective against cancer cells

Researchers at the University of Copenhagen have explored the active principles of a Danish mushroom and found that some of the substances it contains are particularly toxic towards cancer cells. The goal is to synthesise and refine substances in the mushroom that may be useful in future drug development.

9 Dec 2011

Dietary fibers from brown algae help people lose more weight

A new research project conducted at the Faculty of Life Sciences (LIFE), University of Copenhagen, shows that dietary fibres from brown algae boost the sensation of satiety, thereby making people eat less and lose more weight.

9 Dec 2011

Galectin Therapeutics to initiate GM-CT-01 Phase 1/2 combination study in advanced MM

Galectin Therapeutics, the Cancer Centre at the Cliniques universitaires Saint-Luc and the Ludwig Institute for Cancer Research (LICR) announced today that they will initiate a Phase 1/2 safety and efficacy trial testing a novel treatment combination in patients with advanced metastatic melanoma.

9 Dec 2011

Toyota's lean approach might be beneficial to medical procedures

Japanese vehicle manufacturer, Toyota, is well-known for developing the principles of so-called "lean manufacturing". Research published in the International Journal of Technology Management suggests that the lean approach might also be beneficial to medical procedures, making hospitals more efficient and cut waiting lists.

9 Dec 2011

Breakthrough advance in tackling dangerous 'bad' cholesterol in the body

Scientists from the University of Leicester and University of California Los Angeles (UCLA) have announced a breakthrough advance in tackling dangerous 'bad' cholesterol in the body.

9 Dec 2011

Global health R&D funding from wealthy nations fell 6% in 2010, annual G-FINDER report finds

"A group that tracks funding for neglected diseases released its fourth annual report Wednesday, showing for the first time since 2007 a decrease in government and public spending in global health research and development," the Center for Global Health Policy's "Science Speaks" blog reports.

8 Dec 2011

Working night shifts may raise risk of diabetes: Study

About 26% percent of the American workforce, including health-care workers and sanitation staff, need to work night shifts. Earlier research has shown that regular night shifts may disrupt the circadian rhythm, raising the risk of heart disease, obesity, ulcers and even depression.

8 Dec 2011

Breakfast cereals high in sugars: Report

In a new report by the Environmental Working Group, 84 popular brands of breakfast cereals were reviewed. The report suggested that many of these contain a high amount of sugar.

8 Dec 2011

First Edition: December 8, 2011

In today's headlines, reports about the HHS decision on the Plan B morning after pill, as well as the latest progress reports from Capitol Hill on the payroll tax break extension and the doc fix.

8 Dec 2011