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New NIH grant to continue exploration of Fusobacterium nucleatum-associated Beta-Defensin Inducer

Research from Case Western Reserve University School of Dental Medicine to study an isolated agent from common oral bacteria may hold the answer as to how human beta defensins (HBDs)-nature's way of keeping oral microbes from entering the body and wreaking havoc with our health-can be used to create new treatments to block bacteria from entering through the epithelial linings on and in the body.

4 Oct 2011

Senate Republicans doubt prospects for 'grand bargain'

A month into the super committee's term, Senate Republicans are telling K Street that they don't believe the powerful deficit-cutting panel can reach a "grand bargain" agreement, sources familiar with the negotiations say. But the only way that a grand bargain could pass muster with the GOP, the Senate Republican aides say, is if it were tied to an overhaul of Social Security or the controversial proposal by Rep. Paul Ryan (R-Wis.) to turn Medicare into a voucher-based system for future recipients.

4 Oct 2011

Researchers gain insight on how roundworm's brain operates as it moves

Using new optical equipment, a team of 11 researchers put roundworms into a world of virtual reality, monitored both their behavior and brain activity and gained unexpected information on how the organism's brain operates as it moves.

4 Oct 2011

Pakistan facing dengue outbreak, humanitarian aid shortages for flood victims

"More than 12,000 have been infected and 125 people have died over the past two months in Pakistan after coming down with dengue fever, a health department spokesman said Friday," CNN reports.

4 Oct 2011

Sequenom launches iPLEX ADME PGx panel to genotype polymorphisms

Sequenom, Inc., a life sciences company providing innovative genetic analysis solutions, today announced the launch of its iPLEX ADME PGx panel developed to genotype polymorphisms in genes associated with drug absorption, distribution, metabolism, and excretion (ADME).

4 Oct 2011

Dramatic rise in U.S. incidence of oropharyngeal cancer can be attributed to HPV infection

A new study of oropharyngeal cancer suggests that dramatic increases in U.S. incidence of the cancer and survival since 1984 can be attributed to infection with the human papillomavirus.

4 Oct 2011

CRT, Cancer Research UK establish group of scientists with expertise in lipid metabolism

Cancer Research Technology, Cancer Research UK's commercial arm, has established a group of scientists with expertise in lipid metabolism - getting energy from fats and making building blocks for cell growth - to develop targets for potential new cancer drugs.

4 Oct 2011

Karo Bio initiates patient recruitment in eprotirome phase III trial for HeFH

The first patient has now been included in Karo Bio's phase III trial with eprotirome. A total of 630 patients with the hereditary condition HeFH will be studied for safety, and to confirm the beneficial effects on LDL-cholesterol that has been shown previously.

4 Oct 2011

India launches month-long campaign to promote awareness of public hygiene

India's minister of development is promoting a campaign on public hygiene, after a UNICEF report found "that India accounts for 58 percent of the world's population practicing open defecation," the Associated Press/Washington Post reports.

4 Oct 2011

Many average-risk women receive genetic testing for hereditary breast, ovarian cancers

Too many average-risk women and too few high-risk women receive genetic counseling and testing for hereditary breast and ovarian cancers, research shows. Experts at The University of Texas MD Anderson Cancer Center share advice to help patients and their doctors better evaluate family history and make more sound decisions about who should be tested.

4 Oct 2011

Communities That Care system decreases alcohol use, smoking and violence in teens

Delaying the age when kids try alcohol or smoking decreases the likelihood that they will become dependent later in life. Effective interventions exist, but community disagreements about which programs to try can stymie decisions.

4 Oct 2011

Life Technologies, CHEO researcher partner to co-develop microbial detection tests

The Children's Hospital of Eastern Ontario (CHEO) Research Institute is pleased to announce that one of its principal investigators in infectious disease has signed a contract with Life Technologies, an internationally renowned biotech tools company headquartered in Carlsbad, California, to share information that will help to develop tests that uniquely amplify and detect the DNA coding for infectious diseases.

4 Oct 2011

Lipomannan on TB bacterium's outer cell surface can block TNF production

The bacterium that causes tuberculosis has a unique molecule on its outer cell surface that blocks a key part of the body's defense. New research suggests this represents a novel mechanism in the microbe's evolving efforts to remain hidden from the human immune system.

4 Oct 2011

DNA primer vaccine enhances immune response to H5N1 avian influenza vaccine

The immune response to an H5N1 avian influenza vaccine was greatly enhanced in healthy adults if they were first primed with a DNA vaccine expressing a gene for a key H5N1 protein, researchers say.

4 Oct 2011

Researchers discover cell differentiation mechanism

Researchers from the Haematopoietic Differentiation and Stem Cell Biology group at the Centre for Genomic Regulation (CRG), have described one of the mechanisms by which a cell (from the skin, for example) can be converted into another which is completely different.

4 Oct 2011

ICREA researcher has set up spin-off Supragen at IRB Barcelona

Roger Gomis, ICREA researcher at the Institute of Research in Biomedicine (IRB Barcelona) has set up the spin-off Supragen. With the support of IRB Barcelona and the Instituci- Catalana de Recerca i Estudis Avan-ats (ICREA), this initiative is the second biotech company to emerge from the institute since June and the third since this centre was set up towards the end of 2005.

4 Oct 2011

Higher maternal diet quality may reduce risk of birth defects

Healthier dietary choices by pregnant women are associated with reduced risks of birth defects, including neural tube defects and orofacial clefts, according to a study published Online First by the Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.

4 Oct 2011

Depression frequently seems to uncouple 'Hate Circuit' in the brain

A new study using MRI scans, led by Professor Jianfeng Feng, from the University of Warwick's Department of Computer Science, has found that depression frequently seems to uncouple the brain's "Hate Circuit".

4 Oct 2011

Three Penn labs receive NIH grant to speed translation of medical research into patient care

Three labs from the University of Pennsylvania have received $12.5 million from the National Institutes of Health (NIH) as part of its $143.8 million national grant program to challenge the scientific status quo with innovative ideas that have the potential to speed the translation of medical research into improved health for the American public.

4 Oct 2011

New review finds inconsistency in studies that examine link between CCSVI and MS

Studies that examined the possible link between vein blockages and multiple sclerosis are so inconsistent that it's impossible to reach a firm conclusion about the controversial theory, a new review has found.

4 Oct 2011

Research News and Research

New NIH grant to continue exploration of Fusobacterium nucleatum-associated Beta-Defensin Inducer

Senate Republicans doubt prospects for 'grand bargain'

Researchers gain insight on how roundworm's brain operates as it moves

Pakistan facing dengue outbreak, humanitarian aid shortages for flood victims

Sequenom launches iPLEX ADME PGx panel to genotype polymorphisms

Dramatic rise in U.S. incidence of oropharyngeal cancer can be attributed to HPV infection

CRT, Cancer Research UK establish group of scientists with expertise in lipid metabolism

Karo Bio initiates patient recruitment in eprotirome phase III trial for HeFH

India launches month-long campaign to promote awareness of public hygiene

Many average-risk women receive genetic testing for hereditary breast, ovarian cancers

Communities That Care system decreases alcohol use, smoking and violence in teens

Life Technologies, CHEO researcher partner to co-develop microbial detection tests

Lipomannan on TB bacterium's outer cell surface can block TNF production

DNA primer vaccine enhances immune response to H5N1 avian influenza vaccine

Researchers discover cell differentiation mechanism

ICREA researcher has set up spin-off Supragen at IRB Barcelona

Higher maternal diet quality may reduce risk of birth defects

Depression frequently seems to uncouple 'Hate Circuit' in the brain

Three Penn labs receive NIH grant to speed translation of medical research into patient care

New review finds inconsistency in studies that examine link between CCSVI and MS

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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