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UnitedHealth Group's consolidated first-quarter 2010 revenues increase 5% to $23.2 billion

UnitedHealth Group today reported first quarter results, including better-than-projected membership and services growth and effective cost management across its businesses. Financial metrics were in line with or better than Company expectations.

20 Apr 2010

Genetic defect in protein glycogenin can lead to cardiac arrest

Researchers have discovered a new disorder linked to heart problems that stems from a genetic defect in the protein glycogenin. In a worst case scenario, disruption of this protein's function can lead to cardiac arrest, which is exactly what happened to the young man whose case triggered the investigation at Sahlgrenska University Hospital at the University of Gothenburg, Sweden, that led to a brand new diagnosis.

20 Apr 2010

NextBio announces new Sequence-Centric module for mining high throughput array and sequencing data

NextBio today announced the latest evolution of its innovative life science research platform, adding new capabilities for the integration and mining of high-throughput array and next-generation sequencing data. The new NextBio Sequence-Centric module enables researchers to effectively explore and utilize massive amounts of public and internally generated sequencing data, while allowing organizations to create corporate-wide genomic data platforms to serve the needs of their global research teams.

20 Apr 2010

Blood test to determine inflammation levels in body may help assess colon cancer risk: Study

A blood test used to determine the level of inflammation in the body may offer some help in assessing colon cancer risk, according to results of a study to be presented by Vanderbilt-Ingram Cancer Center's Gong Yang, M.D., MPH, at the 101st Annual Meeting of the American Association for Cancer Research.

20 Apr 2010

RANKL inhibition may prove effective in treatment of human malignancy, suggests study

Amgen today announced results of a preclinical study demonstrating a positive response to administration of RANK-Fc against mammary tumor formation in mouse models. OPG-Fc and RANK-Fc bind to and block the action of RANKL. These molecules have a comparable mechanism of action to denosumab. The study was presented today in a late-breaking abstract at the American Association for Cancer Research (AACR) 101st Annual Meeting 2010 in Washington, D.C.

20 Apr 2010

Researchers evaluate probiotics' curative effects for treating ulcerative colitis

Inflammatory bowel disease is a chronic recurrent disease, which mainly consists of ulcerative colitis and Crohn's disease, and whose causes are as yet unclear. Many clinical and research studies have indicated that intestinal flora dysbacteriosis contributes to the pathogenesis of ulcerative colitis. Probiotics are non-pathogenic beneficial flora, which have important effects on maintaining the balance of intestinal flora.

20 Apr 2010

Artificial human skin with dermis made from fibrin-agarose biomaterial

Scientists from the University of Granada, Spain, have generated artificial human skin by tissular engineering basing on agarose-fibrin biomaterial. The artificial skin was grafted onto mice, and optimal development, maturation and functionality results were obtained. This pioneering finding will allow the clinical use of human skin and its use in many laboratory tests on biological tissues -which, additionally, would avoid the use of laboratory animals.

20 Apr 2010

Global guidelines for testing regimes for breast cancer patients

A cancer research specialist from the University of the West of England, Bristol is one of a panel of international experts who have had a report published in the Journal of Clinical Oncology today that gives new global guidelines for testing regimes for breast cancer patients. The guidelines relate to cancer patients with oestrogen and progesterone receptor positive breast tumours.

20 Apr 2010

Forgetfulness, procrastination related to prescription drugs costs $163 billion in wasteful healthcare spending

Express Scripts is the first organization ever to quantify the hidden healthcare costs of very common behaviors related to prescription drugs, such as forgetfulness and procrastination, estimating the annual wasteful spending at $163 billion.

20 Apr 2010

Severe and necrotizing AP characterized by depletion of circulating lymphocytes

Mortality of patients with severe acute pancreatitis (SAP) approaches 30%-40%. An imbalance between the early systemic inflammatory response syndrome (SIRS), and the later compensatory counter-inflammatory response, and development of multiple organ failure (MOF) are considered to be the primary causes of morbidity and mortality in SAP. Excessive leukocyte activation (including neutrophils and monocyte-macrophage lineage) with cytokinemia play a critical role in the pathogenesis of pancreatitis and even more so, of the subsequent inflammatory response.

20 Apr 2010

Certain genetic mutations lead to Type 1 diabetes: The Scripps Research Institute

Scientists from The Scripps Research Institute have provided an answer to the 40-year-old mystery of how certain genetic mutations lead to Type 1 diabetes. This new molecular understanding could lead to novel therapies for Type 1 diabetes and other autoimmune diseases.

20 Apr 2010

PIPC chairman encourages racial, ethnic minority Americans to get involved in CER studies

The chairman of the Partnership to Improve Patient Care, Tony Coelho, encouraged racial and ethnic minority Americans to get more involved in comparative effectiveness research studies as a way to ensure that African Americans and other people of color have access to the latest treatment options and research available.

20 Apr 2010

AHRQ report shows highest hospital readmission rates among Medicaid patients

One of every 10 adult Medicaid patients who were hospitalized in 2007 for a medical condition other than childbirth had to be readmitted at least once within 30 days of their initial hospital stay that year, according to the latest News and Numbers from the Agency for Healthcare Research and Quality.

20 Apr 2010

NFID, LWW form new publishing partnership

The National Foundation of Infectious Disease and Lippincott Williams & Wilkins are pleased to announce the formation of a new publishing partnership. The NFID is a non-profit, tax-exempt organization founded in 1973 dedicated to educating the public and healthcare professionals about the causes, treatment and prevention of infectious diseases.

20 Apr 2010

Pre-clinical study results of BiTE antibody technology presented at AACR 2010

Micromet, Inc., a biopharmaceutical company focused on the development and commercialization of next-generation antibodies for the treatment of cancer, today announced that results from studies highlighting pre-clinical advances with its proprietary BiTE antibody technology were presented at the American Association for Cancer Research Annual Meeting in Washington, DC.

20 Apr 2010

Gamma-prime fibrinogen test can help better predict people at risk for heart attack

A simple blood test can identify people who are at risk for a heart attack, including thousands who don't have high cholesterol, according to researchers at Oregon Health & Science University.

20 Apr 2010

NanoBio to develop intranasal vaccine for HBV

NanoBio® Corporation today announced an initiative to develop an intranasal vaccine for the treatment of hepatitis B (HBV). NanoBio and the University of Michigan's, Michigan Nanotechnology Institute for Medicine and Biological Sciences received funding through a Phase 1 Technology Transfer (STTR) award by the National Institutes of Health (NIH), to evaluate a potential therapeutic intranasal vaccine for the treatment of hepatitis B in patients.

20 Apr 2010

New report studies healthcare market in Europe and provides insights, analysis up to 2014

Healthcare has always been an area of utmost importance. It has significant economic relevance and has been allocated a higher percent of gross domestic product in many countries compared to most other sectors such as transport and communication, construction and education. Healthcare also has a huge impact on employment, for the fact that most related activities are provided by people.

20 Apr 2010

AstraZeneca/Targacept's TC-5214 for treatment resistant depression to earn Decision Resources' gold standard status

Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that, for treatment resistant depression therapy, AstraZeneca/Targacept's TC-5214 will earn Decision Resources' proprietary clinical gold standard status in 2013 (following its approval that year) and through 2018.

20 Apr 2010

Magnetically guided nanoparticles for delivering DNA, cells and drugs

Scientists and engineers have used uniform magnetic fields to drive iron-bearing nanoparticles to metal stents in injured blood vessels, where the particles deliver a drug payload that successfully prevents blockages in those vessels. In this animal study, the novel technique achieved better results at a lower dose than conventional non-magnetic stent therapy.

20 Apr 2010

Research News and Research

UnitedHealth Group's consolidated first-quarter 2010 revenues increase 5% to $23.2 billion

Genetic defect in protein glycogenin can lead to cardiac arrest

NextBio announces new Sequence-Centric module for mining high throughput array and sequencing data

Blood test to determine inflammation levels in body may help assess colon cancer risk: Study

RANKL inhibition may prove effective in treatment of human malignancy, suggests study

Researchers evaluate probiotics' curative effects for treating ulcerative colitis

Artificial human skin with dermis made from fibrin-agarose biomaterial

Global guidelines for testing regimes for breast cancer patients

Forgetfulness, procrastination related to prescription drugs costs $163 billion in wasteful healthcare spending

Severe and necrotizing AP characterized by depletion of circulating lymphocytes

Certain genetic mutations lead to Type 1 diabetes: The Scripps Research Institute

PIPC chairman encourages racial, ethnic minority Americans to get involved in CER studies

AHRQ report shows highest hospital readmission rates among Medicaid patients

NFID, LWW form new publishing partnership

Pre-clinical study results of BiTE antibody technology presented at AACR 2010

Gamma-prime fibrinogen test can help better predict people at risk for heart attack

NanoBio to develop intranasal vaccine for HBV

New report studies healthcare market in Europe and provides insights, analysis up to 2014

AstraZeneca/Targacept's TC-5214 for treatment resistant depression to earn Decision Resources' gold standard status

Magnetically guided nanoparticles for delivering DNA, cells and drugs

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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