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EGFR levels may help early detection of breast cancer

Levels of epidermal growth factor receptor (EGFR) may be elevated in the blood of women within 17 months prior to their breast cancer diagnosis, according to findings presented at the American Association for Cancer Research 101st Annual Meeting 2010, held here April 17-21.

21 Apr 2010

Preclinical data in neuroblastoma for perifosine to be presented at AACR 2010 Meeting

Aeterna Zentaris Inc., a late-stage drug development company specialized in oncology and endocrine therapy, today announced that preclinical data in neuroblastoma for perifosine, the Company's novel, potentially first-in-class, oral anti-cancer agent that inhibits Akt activation in the phosphoinositide 3-kinase pathway, will be presented at the 101st Annual Meeting of the American Association for Cancer Research, currently being held at the Walter E. Washington Convention Center in Washington, DC.

21 Apr 2010

Researchers demonstrate role of HSP-90 in portal hypertension

Neural vasoregulation represents a rapid and potent mode of altering vascular tone but has not been investigated thoroughly during portal hypertension. Heat shock protein-90 is well-known to act as a molecular chaperone optimizing endothelial and neural NO-synthase enzyme activity and thus, NO production.

21 Apr 2010

Concateno bestowed Queen's Award for Enterprise

Concateno (>Europe's leading drug and alcohol test provider, has been awarded the prestigious Queen's Award for Enterprise (http://www.queensawards.org.uk/business/business.html ) in recognition of its outstanding innovation and commercial performance.

21 Apr 2010

A*STAR's BMRC and SIgN award grants for twelve research projects on infectious diseases and immunology

Twelve research projects on infectious diseases and immunology have been awarded grants by A*STAR's Biomedical Research Council (BMRC) and Singapore Immunology Network (SIgN) this year.

21 Apr 2010

MMRC Multiple Myeloma Genomics Initiative presented at AACR 2010

An analysis of 38 myeloma tumor genomes surveyed through extensive next-generation sequencing by the Broad Institute has revealed intriguing recurrent mutations that point to important cellular pathways which contribute to multiple myeloma. These data were revealed during an oral presentation entitled "First Impressions of the Multiple Myeloma Genome" by Todd R. Golub, MD, Director of the Cancer Program at the Eli and Edythe L. Broad Institute.

21 Apr 2010

Tea for Teal event raises $15,000 for TGen ovarian cancer research

The Anne Rita Monahan Foundation recently presented $15,000 for ovarian cancer research to the Translational Genomics Research Institute (TGen).

21 Apr 2010

Contrary to previous studies, people with Moebius syndrome lead successful lives

A smile means happiness, a frown sadness, a raised brow surprise. Even when languages and cultures differ, people have this universal form of communication. But Moebius syndrome, a rare congenital condition causing facial paralysis, can rob people of this basic connection, affecting social interaction.

21 Apr 2010

Researchers discover subunits of GABAB receptors in central nervous system

In the latest issue of the renowned scientific journal "Nature" researchers from the universities of Freiburg and Basel report on their discovery of previously unknown subunits of the GABAB receptors in the central nervous system. GABAB receptors are transmembrane proteins in nerve cells which are of fundamental significance for the functioning of the brain and have great therapeutical and pharmaceutical importance.

21 Apr 2010

New research shows mercury levels are higher in some tuna species

New research showing that that mercury levels are higher in some species of tuna could help consumers minimize their consumption of the silvery metal in their sushi and provide a powerful new tool for regulatory organizations.

21 Apr 2010

Simcyp wins Queen's Award for Enterprise for innovative research and development

Simcyp Limited, experts in simulating how the body deals with new drugs in development, today announces that it has won a Queen's Award for Enterprise. The award has been made in the Innovation category and reflects Simcyp's continuous development of modelling and simulation software for evaluating drugs in the safety of a computer.

21 Apr 2010

Modest weight reduction reverses immune cell damage in obese people with diabetes

Australian scientists have shown for the first time that even modest weight loss reverses many of the damaging changes often seen in the immune cells of obese people, particularly those with Type 2 diabetes.

21 Apr 2010

Study identifies the source of inherent noise in HIV gene expression

New research identifies a molecular mechanism that the human immunodeficiency virus (HIV) appears to utilize for generating random fluctuations called "noise" in its gene expression.

21 Apr 2010

Children with developmental regression at increased risk for more severe autism: Study

Kennedy Krieger Institute announced today new study results showing that when and how autism symptoms appear in the first three years of life has vital implications to a child's developmental, diagnostic, and educational outcomes.

21 Apr 2010

Hearing tests needed for children

The importance of hearing testing isn't widely understood by many parents. Parents may schedule appointments with an opthamologist for an eye exam for their children at regular intervals - but never think to similarly schedule a hearing test with an audiologist.

21 Apr 2010

Plexxikon presents promising preclinical data from PLX3397 in vivo cancer studies

Plexxikon Inc. today announced promising preclinical data from in vivo cancer studies with PLX3397 demonstrating significant reduction in tumor burden, metastatic spread, bone erosion and cancer bone pain. PLX3397 is an oral, selective kinase inhibitor that down-modulates macrophages, microglia, osteoclasts and mast cells, all cell types targeted by this drug candidate. These cell types play a key role in cancer and metastasis.

21 Apr 2010

Researchers screen Afro-Caribbean students to predict risk of heart disease

Researchers at the University of Hertfordshire are screening an Afro-Caribbean cohort of students this week to gauge their predisposition to heart disease in later life.

21 Apr 2010

Gene test predicts statins' effectiveness in reducing risk of colorectal cancer

A genetic test can help determine in which patients cholesterol-lowering statin drugs might have the most benefit in also reducing the risk of colorectal cancer, a new study from researchers at the University of Michigan Comprehensive Cancer Center finds.

21 Apr 2010

Vitamin D intake from foods, supplements may not predict relationship between cancer and vitamin D

Vitamin supplements, diet, geographic location, demographic information or lifestyle, independently or in combination, cannot accurately predict vitamin D concentrations in blood, researchers at the University at Buffalo have found.

21 Apr 2010

Unwarranted increase in use of psychotropic medications for children

A new study from the Journal of Marital & Family Therapy warns of the dramatic rise in the use of psychotropic medications for children. One in every fifty Americans is now considered permanently disabled by mental illness, and up to eight million children take one or more psychotropic drugs.

21 Apr 2010

Research News and Research

EGFR levels may help early detection of breast cancer

Preclinical data in neuroblastoma for perifosine to be presented at AACR 2010 Meeting

Researchers demonstrate role of HSP-90 in portal hypertension

Concateno bestowed Queen's Award for Enterprise

A*STAR's BMRC and SIgN award grants for twelve research projects on infectious diseases and immunology

MMRC Multiple Myeloma Genomics Initiative presented at AACR 2010

Tea for Teal event raises $15,000 for TGen ovarian cancer research

Contrary to previous studies, people with Moebius syndrome lead successful lives

Researchers discover subunits of GABAB receptors in central nervous system

New research shows mercury levels are higher in some tuna species

Simcyp wins Queen's Award for Enterprise for innovative research and development

Modest weight reduction reverses immune cell damage in obese people with diabetes

Study identifies the source of inherent noise in HIV gene expression

Children with developmental regression at increased risk for more severe autism: Study

Hearing tests needed for children

Plexxikon presents promising preclinical data from PLX3397 in vivo cancer studies

Researchers screen Afro-Caribbean students to predict risk of heart disease

Gene test predicts statins' effectiveness in reducing risk of colorectal cancer

Vitamin D intake from foods, supplements may not predict relationship between cancer and vitamin D

Unwarranted increase in use of psychotropic medications for children

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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