Respiratory News and Research

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Selecting SARS-CoV-2 inhibitors in human airway epithelial cells

In a recent article currently available on the bioRxiv* preprint server, researchers from Belgium and the U.S. demonstrated a robust replication model for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) isolates in primary human epithelial cells at the air-liquid interface and appraised the antiviral effect of selected viral replication inhibitors.

28 Mar 2021

Covid-19 lockdown restrictions may have led to reduction in asthma exacerbations

Fewer patients with severe attacks were seen by their GP or admitted to hospital during the covid-19 pandemic, and fewer were admitted to hospital for pneumonia, influenza and chronic lung diseases, show findings from three papers published online in the journal Thorax.

27 Mar 2021

POSTECH researchers produce artificial lung model using 3D printing

The warmer temperature and blooming flowers signal the arrival of spring. However, worries about respiratory diseases are also on the rise due to fine dust and viruses.

26 Mar 2021

Demographic and clinical comparison of the first and second COVID-19 waves in London, UK

In a paper recently uploaded to the preprint server medRxiv*, clinical and demographic data from across the UK is compared to viral genome sequence data, identifying trends amongst the population affected, and across SARS-CoV-2 strains.

26 Mar 2021

Longitudinal study of SARS-CoV-2 antibodies following vaccination

A longitudinal study of IgG antibody levels in vaccinated healthcare workers was recently uploaded to the preprint server medRxiv*, suggesting that IgG levels could be a reliable indicator of successful vaccination.

26 Mar 2021

Testing unavailability may influence public behaviors and facilitate SARS-CoV-2 transmission

A team of scientists from the University of California, Los Angeles, USA, recently conducted a survey investigating the association between availability of testing facilities and COVID-19-related behavioral aspects. Their findings reveal that testing unavailability independently influences certain COVID-19-related behaviors that may increase the risk of SARS-CoV-2 transmission.

26 Mar 2021

Occupation not a reason for high COVID-19 rates among immigrants in Norway, finds study

A new study has found that the disproportionate rate of COVID-19 among immigrant groups in Norway may not be a result of occupational risks.

26 Mar 2021

New mathematical model identifies role of super-spreaders in SARS-CoV-2 variant emergence

Researchers have developed a new mathematical model which helps characterize factors responsible for the emergence of new SARS-CoV-2 variants and their predominance.

26 Mar 2021

COVID-19 pandemic lockdown measures have caused body weight increases in U.S., finds study

Researchers from the University of California, San Francisco, studied the body weight changes of a longitudinal cohort during the initial SIP (shelter-in-place) orders to better understand the possible downstream health implications of a prolonged SIP. They found a significant increase in body weight over the post-SIP period at a rate of roughly a pound and a half weight gain per month following SIP.

26 Mar 2021

The pressure is on to diagnose and treat chronic kidney disease

In this interview, Helen Yeh, the Vice President, Biopharmaceuticals Medical, Cardiovascular, Renal and Metablosim at AstraZeneca , talks News-Medical to about chronic kidney diseas (CKD).

From AstraZeneca 26 Mar 2021

COVID-19 long haulers report persistent neurological symptoms

Researchers at Northwestern University, USA, analyzed "long hauler" patients whose symptoms lasted at least six weeks. They found persistent neurological symptoms, including brain fog and headache.

26 Mar 2021

Can COVID-19 cause hearing loss, vertigo, and tinnitus?

Researchers at the University of Manchester, UK, aimed to systematically review the literature to provide evidence on SARS-CoV-2 and audio-vestibular symptoms. They found that COVID-19 has been tied to hearing loss, vertigo, and tinnitus.

26 Mar 2021

Combination of X-rays and AI can serve as rapid diagnostic tool for COVID-19

X-rays, first used clinically in the late 1890s, could be a leading-edge diagnostic tool for COVID-19 patients with the help of artificial intelligence, according to a team of researchers in Brazil who taught a computer program, through various machine learning methods, to detect COVID-19 in chest X-rays with 95.6 to 98.5% accuracy.

26 Mar 2021

Identification of specific anti-SARS-CoV-2 antibodies with cross-neutralization potency

A team of scientists from the USA and Canada recently characterized the cross-neutralizing potency of anti-SARS-CoV-2 antibodies isolated from COVID-19 patients. The findings reveal that some of the isolated antibodies targeting the spike RBD and the S2 subunit are capable of cross-neutralizing other members of the human beta-coronavirus family.

25 Mar 2021

Apply for your NObreath® FeNO breath monitor today and optimise patient asthma care

NHS Organisations can apply for funding from the Pathway Transformation Fund (PTF) to obtain a NObreath® used for asthma diagnosis and management.

25 Mar 2021

Dual-antigen COVID-19 vaccine elicits humoral and cellular immune responses in mice

The scientific consensus is that safe and highly effective vaccines are required to end the ongoing pandemic of coronavirus disease 2019 COVID-19, caused by SARS-CoV-2. A new study describes a new vaccine that presents two viral antigens to the human immune system, in order to elicit a more efficacious response.

25 Mar 2021

Could an mRNA vaccine second dose reduce cellular immunity in previously infected individuals?

A new study, which was released on the bioRxiv* preprint server, shows the differential effect that a standard vaccine protocol may have on individuals, based on their history of prior infection with the virus.

25 Mar 2021

Could dry swabs provide cheaper, safer and faster material for SARS-CoV-2 testing?

A new study deals with the feasibility of using dry swab samples to isolate the virus, as compared to wet swabs, to reduce costs while improving safety.

25 Mar 2021

Researchers find evidence that SARS-CoV-2 infects cells in the mouth

An international team of scientists has found evidence that SARS-CoV-2, the virus that causes COVID-19, infects cells in the mouth.

25 Mar 2021

Researchers examine SARS-CoV-2 RNA interactome

A new study focuses on the identification of RNA-binding protein by mass spectrometry (ChIRP-M/S) approach. This study develops a global map that contains the complete set of host proteins that involve the SARS-CoV-2 genome during infection. This study has successfully identified new SARS-CoV-2 host dependency factors by merging proteomics data with gene silencing experiments. Such a discovery has paved new roads to develop more antiviral therapies.

25 Mar 2021

Respiratory News and Research

Selecting SARS-CoV-2 inhibitors in human airway epithelial cells

Covid-19 lockdown restrictions may have led to reduction in asthma exacerbations

POSTECH researchers produce artificial lung model using 3D printing

Demographic and clinical comparison of the first and second COVID-19 waves in London, UK

Longitudinal study of SARS-CoV-2 antibodies following vaccination

Testing unavailability may influence public behaviors and facilitate SARS-CoV-2 transmission

Occupation not a reason for high COVID-19 rates among immigrants in Norway, finds study

New mathematical model identifies role of super-spreaders in SARS-CoV-2 variant emergence

COVID-19 pandemic lockdown measures have caused body weight increases in U.S., finds study

The pressure is on to diagnose and treat chronic kidney disease

COVID-19 long haulers report persistent neurological symptoms

Can COVID-19 cause hearing loss, vertigo, and tinnitus?

Combination of X-rays and AI can serve as rapid diagnostic tool for COVID-19

Identification of specific anti-SARS-CoV-2 antibodies with cross-neutralization potency

Apply for your NObreath® FeNO breath monitor today and optimise patient asthma care

Dual-antigen COVID-19 vaccine elicits humoral and cellular immune responses in mice

Could an mRNA vaccine second dose reduce cellular immunity in previously infected individuals?

Could dry swabs provide cheaper, safer and faster material for SARS-CoV-2 testing?

Researchers find evidence that SARS-CoV-2 infects cells in the mouth

Researchers examine SARS-CoV-2 RNA interactome

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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