Respiratory News and Research

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Only few clinical trials are being conducted to test drugs in pediatric patients

Although children are more likely than adults to suffer from many diseases, few clinical trials are being conducted to test drugs in pediatric patients, according to a study to be presented Saturday, April 28, at the Pediatric Academic Societies (PAS) annual meeting in Boston.

30 Apr 2012

Novartis receives FDA approval for Afinitor to treat renal angiomyolipomas caused by TSC

The U.S. Food and Drug Administration approved Afinitor (everolimus), the first drug approved specifically to treat non-cancerous kidney tumors (renal angiomyolipomas) not requiring immediate surgery in patients with tuberous sclerosis complex.

27 Apr 2012

Study examines role of NLRP3 inflammasome in ventilator-induced lung injury

Mechanical ventilation is often lifesaving, but can also initiate or aggravate lung injury. A new study in the May issue of Anesthesiology examined the role of one particular receptor in the inflammatory pathway, the NLRP3 inflammasome, and whether it impacts ventilator-induced lung injury.

26 Apr 2012

FDA issues complete response letter to Takeda’s NDAs for type 2 diabetes investigational therapies

Takeda Pharmaceutical Company Limited and its wholly-owned subsidiary, Takeda Global Research & Development Center, Inc. today announced that the company received a complete response letter from the United States (U.S.) Food and Drug Administration (FDA) regarding New Drug Applications (NDAs) for alogliptin and fixed-dose combination (FDC) alogliptin and pioglitazone.

26 Apr 2012

London School of Hygiene & Tropical Medicine launches Centre for Global Non-Communicable Diseases

The Centre for Global Non-Communicable Diseases, a unique initiative that brings together researchers, policy makers, funders and patient advocacy groups worldwide to focus research and expertise on this growing global health challenge, is launched today (25 April) at the London School of Hygiene & Tropical Medicine.

25 Apr 2012

Study finds better outcomes in VLBW infants born at RNE hospitals

In a study that included more than 72,000 very low-birth-weight infants, among those born in hospitals with recognition for nursing excellence (RNE), compared with non-RNE hospitals, there was a significantly lower rate of hospital infection, death at 7-days and severe intraventricular hemorrhage but not lower rates of death at 28-days or hospital stay mortality, according to a study in the April 25 issue of JAMA.

24 Apr 2012

Robot-assisted surgery more common and successful in treating prostate cancer

Robot-assisted surgery is now both more common and far more successful than radical "open" surgery to treat prostate cancer in the United States, according to a new Henry Ford Hospital study published in the current issue of the medical journal European Urology.

24 Apr 2012

Cancer therapy with common cold virus

Common viruses have become the latest weapon against cancer. There is the case of the eight-year-old African boy diagnosed with Burkitt's lymphoma at a Ugandan health clinic. He was exposed to the measles virus and in the next few weeks his tumour regressed completely and he entered remission. But only relatively recently have scientists clinically examined the interaction between viruses and cancers in the growing area of oncolytic virotherapy.

24 Apr 2012

New drug can prevent exacerbations of asthma due to common cold: Trial report

For the tens of thousands of asthma sufferers in the UK there is a “breakthrough” drug that reduces complications caused by the common cold, it is claimed.

22 Apr 2012

Researchers discover novel genetic mechanism of idiopathic CD4 lymphopenia

Researchers at National Jewish Health have discovered a novel genetic mechanism of immune deficiency. Magdalena M. Gorska, MD, PhD, and Rafeul Alam, MD, PhD, identified a mutation in Unc119 that causes immunodeficiency known as idiopathic CD4 lymphopenia.

21 Apr 2012

Positive data from Synairgen’s SNG001 Phase II trial on asthma

Scientists from the University of Southampton and Synairgen, a respiratory drug development company spun out from the University, can announce positive data from its Phase II clinical trial, into the effectiveness of the drug SNG001 (inhaled interferon beta) for asthma patients.

20 Apr 2012

Soldiers, farmers can have common chronic exposure to nerve impacting chemicals

Soldiers in war zones and farmers tending their fields can have in common chronic exposure to chemicals that impact their nerves.

19 Apr 2012

Earth Day prompts examination of health-care providers' roles in climate change

Physicians and nurses have a role if not "a moral and professional responsibility to act" to help to reduce climate change and help those impacted, say the authors of "Climate Change & Health: Is There a Role for the Health Care Sector?," published by the Catholic Health Association of the United States.

18 Apr 2012

Washington Post examines research assessing public health benefits of clean cookstoves

"One of the most talked-about public-health initiatives is improving indoor air quality in the rural developing world," the Washington Post reports, noting "Over the past two years, the United States has pledged $105 million to fighting the cookstove problem."

18 Apr 2012

Flu outbreak at veterans home

State Veterans' Affairs Commissioner Linda Schwartz told The Associated Press that the veterans were taken to Hartford Hospital after a number began complaining of flu-like symptoms. The 18 men live at the Connecticut State Veterans Home in either the Sgt. John L. Levitow Veteran's Health Center or a residential facility.

17 Apr 2012

FDA grants 510(k) clearance for QIAGEN’s molecular detection PCR technology

QIAGEN N.V. today announced that the U.S. Food and Drug Administration (FDA) has granted two 510(k) clearances for its real-time PCR (polymerase chain reaction) instrument Rotor-Gene Q MDx and a compatible test for the detection of Influenza A/B, the artus Infl A/B RG RT-PCR Kit, for in vitro diagnostic use.

From QIAGEN Manchester Limited 17 Apr 2012

UVA engineer and biologist named recipients of Hartwell Individual Biomedical Research Awards

University of Virginia engineer Silvia Salinas Blemker and biologist Christopher Deppmann have been named recipients of 2011 Hartwell Individual Biomedical Research Awards, which provide $100,000 in annual research support for three years to each awardee.

16 Apr 2012

ACAAI to conduct 16th annual Nationwide Asthma Screening Program

The unseasonably warm weather is making this spring season difficult for millions of Americans who suffer from asthma and allergies. To help adults and children who have symptoms find out if they are at risk, allergists will conduct the 16th annual Nationwide Asthma Screening Program, expanding the program this year to include screening for nasal allergies.

16 Apr 2012

Toxic plants and animal products found in traditional Chinese medicines

A study has found that some traditional Chinese medicines contain potentially poisonous plants, unlabelled ingredients and bits of endangered animals. This has triggered a bid for routine testing and tighter regulation of complementary medicines.

15 Apr 2012

Bahrain: Despite reforms access to healthcare still a concern, says Médecins Sans Frontières

As Bahrain implements reforms following protests that started last year, a significant number of patients – from all political and religious backgrounds - continue to avoid seeking medical care in public hospitals due to perceived discrimination, harassment, and ill treatment, the international medical humanitarian organisation Médecins Sans Frontières said today.

12 Apr 2012