Respiratory Disease News and Research

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History of COVID-19 increases risk of fatigue and other long COVID symptoms in adults and children

Researchers observe that COVID-19 patients were at an increased risk of developing certain conditions.

21 Dec 2022

Brief roundup of research done by experts at UCLA Health

Below is a brief roundup of news and story ideas from the experts at UCLA Health.

21 Dec 2022

Immune-evading Mycobacterium tuberculosis prevents inflammatory responses by hijacking the host’s ubiquitin

A new study discussed the findings of Chai et al., which revealed that triple specificity protein phosphatase (ptpB) secreted by Mycobacterium tuberculosis inhibits pyroptosis and the release of cytokines by macrophages, allowing M. tuberculosis to invade the immune system.

19 Dec 2022

Study suggests sleep disturbance is associated with dyspnoea, anxiety, and muscle weakness following COVID-19 hospitalization

Researchers used a multi-modal approach to examine the types, prevalence, and relevance of sleep disturbance in individuals hospitalized with COVID-19 and determine associations between dyspnea and sleep disturbance.

19 Dec 2022

Study shows SARS-CoV-2 infection, replication and persistence in human brain tissues

Researchers investigated the cellular tropism, replication competence, persistence and evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in humans, and associated histopathological changes in infected tissues.

16 Dec 2022

Bad cholesterol and high blood pressure may be associated with higher risk of cardiovascular disease

High levels of lipoprotein(a), a type of "bad" cholesterol, may be associated with an 18-20% higher risk of cardiovascular disease among people who have hypertension, however, CVD risk was not higher among those without hypertension, according to new research published today in Hypertension, an American Heart Association journal.

13 Dec 2022

Single-cell transcriptome analysis provides insights into bat immunity

In a world first, scientists at Duke-NUS Medical School and colleagues in Singapore have sequenced the response to viral infection in colony-bred cave nectar bats (Eonycteris spelaea) at single-cell resolution.

24 Nov 2022

Experts investigate the role of IL-26 in COVID-19

Researchers at Karolinska Institutet in Sweden have shown that patients with acute COVID-19 infection have increased levels of the cytokine IL-26 in their blood. Moreover, high IL-26 levels correlate with an exaggerated inflammatory response that signifies severe cases of the disease. The findings, which are presented in Frontiers in Immunology, indicate that IL-26 is a potential biomarker for severe COVID-19.

17 Nov 2022

Smoking marijuana damages the lungs more than tobacco

Lungs of marijuana smokers exhibit greater levels of airway inflammatory markers and emphysema as compared to those of tobacco-only smokers.

15 Nov 2022

Research sheds light on cardiac pathology mechanisms of COVID-19

Researchers compared cardiac autopsy samples from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) positive cases with age-matched samples from influenza hemagglutinin 1 neuraminidase 1 (H1N1) cases, non-influenza lymphocytic myocarditis cases, and heart tissue with no inflammation to understand the mechanisms underlying the pathology of the cardiac complications during coronavirus disease 2019 (COVID-19).

15 Nov 2022

What is the role of adenoviruses in human health?

With advances in molecular biology informing recent developments in vaccinology, gene therapy, and other fields of medicine, human adenoviruses (HAdVs) have been of primary importance in medical research. A recent review looks at the promises of HAdVs, their potential dangers, and future challenges.

9 Nov 2022

Study suggests anti-PF4 antibodies may play a role in the severe multiorgan disease manifestations of COVID-19

Researchers investigated the association between the increased levels of anti-platelet factor 4 antibodies and the clinical complications of COVID-19.

7 Nov 2022

Researchers use brain organoids to show how SARS-CoV-2 virus infects cortical neurons

Using human brain organoids, an international team of researchers, led by scientists at University of California San Diego School of Medicine and Sanford Consortium, has shown how the SARS-CoV-2 virus that causes COVID-19 infects cortical neurons and specifically destroys their synapses -; the connections between brain cells that allow them to communicate with each other.

3 Nov 2022

Progress and challenges in the development of mRNA vaccines against respiratory syncytial virus

New research discussed the structure and life cycle of respiratory syncytial virus (RSV), the current research on the treatment and prevention of RSV infections, and the advancements in RSV mRNA vaccine technology after the surge in vaccine research during the COVID-19 pandemic.

1 Nov 2022

Severe vitamin D deficiency associated with greater risk of premature mortality

It’s the vitamin that we get from the sun, yet despite its ample availability, one in three Australian adults still suffer from mild, moderate or severe vitamin D deficiency.

26 Oct 2022

COVID-19 and the gut

Researchers summarize current knowledge about underlying mechanisms and potential therapeutic approaches for the effects of COVID-19 on the gut.

26 Oct 2022

A review of emerging pediatric respiratory viruses

Respiratory viruses continue to be a leading cause of childhood morbidity and mortality.

26 Oct 2022

Analysis finds link between cumulative occupational exposure and waning lung capacity

Workplace exposure to gases, dusts, fumes, and aromatic solvents used in paints, varnishes, and glues, is linked to waning lung capacity above and beyond that associated with normal aging, finds a pooled data analysis of the available evidence, published online in the journal Occupational & Environmental Medicine.

25 Oct 2022

What is the function of micronutrients in COVID-19 recovery?

Researchers assessed the function of micronutrients and metabolites derived from gut microbiota in coronavirus disease 2019 (COVID-19) recovery.

18 Oct 2022

Researchers explore the development of mRNA vaccines against respiratory syncytial virus

Recently, researchers discussed the development of messenger ribonucleic acid (mRNA) vaccines against the respiratory syncytial virus (RSV).

17 Oct 2022

Respiratory Disease News and Research

History of COVID-19 increases risk of fatigue and other long COVID symptoms in adults and children

Brief roundup of research done by experts at UCLA Health

Immune-evading Mycobacterium tuberculosis prevents inflammatory responses by hijacking the host’s ubiquitin

Study suggests sleep disturbance is associated with dyspnoea, anxiety, and muscle weakness following COVID-19 hospitalization

Study shows SARS-CoV-2 infection, replication and persistence in human brain tissues

Bad cholesterol and high blood pressure may be associated with higher risk of cardiovascular disease

Single-cell transcriptome analysis provides insights into bat immunity

Experts investigate the role of IL-26 in COVID-19

Smoking marijuana damages the lungs more than tobacco

Research sheds light on cardiac pathology mechanisms of COVID-19

What is the role of adenoviruses in human health?

Study suggests anti-PF4 antibodies may play a role in the severe multiorgan disease manifestations of COVID-19

Researchers use brain organoids to show how SARS-CoV-2 virus infects cortical neurons

Progress and challenges in the development of mRNA vaccines against respiratory syncytial virus

Severe vitamin D deficiency associated with greater risk of premature mortality

COVID-19 and the gut

A review of emerging pediatric respiratory viruses

Analysis finds link between cumulative occupational exposure and waning lung capacity

What is the function of micronutrients in COVID-19 recovery?

Researchers explore the development of mRNA vaccines against respiratory syncytial virus

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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