Restenosis News and Research

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Restenosis means the reoccurrence of stenosis, a narrowing of a blood vessel, leading to restricted blood flow. Restenosis usually pertains to an artery or other large blood vessel that has become narrowed, received treatment to clear the blockage and subsequently become renarrowed. This is usually restenosis of an artery, or other blood vessel, or possibly a vessel within an organ.

Genetically engineered herpes simplex virus keeps arteries free-flowing

A genetically engineered herpes simplex virus, primarily known for causing cold sores, may help keep arteries "free-flowing" in the weeks following angioplasty or stent placement for patients, according to research published early in the online edition of PNAS (Proceedings of the National Academy of Sciences of the United States of America).

11 Jul 2007

3-D plasma coating technique keeps veins and arteries open

Scientists at the University of Ulster are working on a new method of coating stents – the medical devices used to keep veins and arteries open – to prevent them blocking up.

30 May 2007

Safer medical implants

A pair of Florida State University researchers have received a major grant from the National Institutes of Health (NIH) to study ways of preventing the body from developing scar tissue around biomedical devices such as coronary artery stents - a problem that affects thousands of patients each year.

18 May 2007

Stent thrombosis

Over the last year, it's been rare to utter the word "stent" without at least thinking "thrombosis," an uncommon but serious complication that's been on the minds of interventional cardiologists and patients alike.

11 May 2007

Key findings on new-generation stent

New data reported at the 30th Annual Scientific Sessions of the Society for Cardiovascular Angiography and Interventions (SCAI), offered clues to the fate of a new-generation drug-eluting stent that is vying for a place in the treatment of coronary artery disease.

11 May 2007

Recent developments for drug-eluting stents

Drug-eluting stents -- small metal tubes used to prop open clogged arteries -- have been garnering headlines.

10 May 2007

Off-label and untested use of drug-coated stents is common in U.S. practice

The off-label and untested use of drug-coated stents in the treatment of coronary artery blockage is common in U.S. practice, and ischemic complication rates are higher among patients receiving drug-coated stents for off-label indications, according to two studies in the May 9 issue of Journal of the American Medical Association.

9 May 2007

Micell Technologies presents data on novel drug-eluting stents

Micell Technologies has announced that the Company will be presenting data on use of its supercritical fluid (SCF) surface modification technology for drug-eluting stents at the upcoming Society for Biomaterials 2007 Annual Meeting, April 19-21 2007 in Chicago, Illinois.

19 Apr 2007

Adding estradiol to a polymer-free rapamycin-eluting stent is not associated with any measurable benefit

Patients admitted to the hospital with acute coronary syndromes (ACS) are often treated with a catheter-based procedure known as percutaneous coronary intervention (PCI), during which a stent is inserted into an occluded or narrowed coronary artery to restore blood flow to and from the heart.

2 Apr 2007

Drug-eluting stents are disappointing in bypass grafts - sometimes!

While drug-eluting stents are effective in keeping open bypassed heart veins that aren?t too diffuse (filled with cholesterol plaque), a new study by cardiologists at Jefferson Medical College shows that they fare less well in keeping open bypassed veins with longer blockages.

2 Apr 2007

Surface analysis of stents

The fastest growing market for surface analysis techniques is in the development and manufacture of vascular stents.

16 Jan 2007

Milk eliminates cardiovascular health benefits of tea

Research published on-line in European Heart Journal has found that the protective effect that tea has on the cardiovascular system is totally wiped out by adding milk.

9 Jan 2007

Milk wipes out heart benefits offered by tea

Research published online in the European Heart Journal has found that the protective effect that tea has on the cardiovascular system is totally wiped out by adding milk.

9 Jan 2007

First drug-eluting stent approved in Europe for most severe form of arterial disease in the leg

Cordis Endovascular, a division of Cordis Corporation, announced today that the Cypher Select Sirolimus-eluting stent received CE (Communite European) Mark in Europe for use in the treatment of severe claudication and critical limb ischemia (CLI) of infrapopliteal lesions, which is the most severe form of arterial disease in the leg.

6 Sep 2006

When to use bare-metal stents, when to use drug-eluting stents

World Congress of Cardiology Report - Drug-eluting stents (DES) are more effective than bare-metal stents (BMS) in reducing restenosis and in repeat interventions after percutaneous coronary interventions (PCI).

5 Sep 2006

New research may solve problem of vessels re-closing after angioplasty

Through studying pigeons with genetic heart disease, researchers at Wake Forest University School of Medicine have discovered a clue about why some patients' heart vessels are prone to close back up after angioplasty.

6 Aug 2006

Australian researchers find key 'go-betweeen' in heart disease

Medical researchers at the University of New South Wales (UNSW) - Australia, have shed light on a little-known mechanism involved in the thickening of arteries, a process associated with heart disease.

13 Mar 2006

Sirolimus-releasing stents more effective than vascular brachytherapy for treating restenosis within a stent

David R. Holmes, Jr., M.D., of Mayo Clinic, Rochester, Minn., and colleagues with the SISR trial compared the use of vascular brachytherapy (VBT - intra-coronary radiation therapy) with implantation of the sirolimus-eluting stent for the treatment of restenosis occurring within a previously placed bare-metal stent

13 Mar 2006

Stents that release the drug paclitaxel to treat stenosis more effective than radiation therapy

Insertion of stents that release the drug paclitaxel to treat stenosis within an implanted bare-metal stent in a coronary artery reduces the risk of subsequent re-narrowing within the stent, when compared with treatment using intra-coronary radiation

13 Mar 2006

Drug-eluting stents best treatment for managing coronary restenosis

In the first published trial of its kind, a multi-center clinical study has shown that drug-eluting stents outperform the current "gold standard" radiation treatment in managing coronary restenosis and in preventing further clogging of coronary arteries.

13 Mar 2006