Restless Legs Syndrome News and Research

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Restless legs syndrome (RLS) is a neurological disorder characterized by unpleasant sensations in the legs and an uncontrollable urge to move when at rest in an effort to relieve these feelings. RLS sensations are often described by people as burning, creeping, tugging, or like insects crawling inside the legs. Often called paresthesias (abnormal sensations) or dysesthesias (unpleasant abnormal sensations), the sensations range in severity from uncomfortable to irritating to painful.

The most distinctive or unusual aspect of the condition is that lying down and trying to relax activates the symptoms. As a result, most people with RLS have difficulty falling asleep and staying asleep. Left untreated, the condition causes exhaustion and daytime fatigue. Many people with RLS report that their job, personal relations, and activities of daily living are strongly affected as a result of their exhaustion. They are often unable to concentrate, have impaired memory, or fail to accomplish daily tasks.
Boehringer Ingelheim Pharmaceuticals receives FDA approval for Mirapex ER in treatment of early PD

Boehringer Ingelheim Pharmaceuticals receives FDA approval for Mirapex ER in treatment of early PD

Depomed receives final meeting minutes from FDA for pre-NDA meeting on DM-1796 for PHN

Depomed receives final meeting minutes from FDA for pre-NDA meeting on DM-1796 for PHN

FDA issues Complete Response Letter for Horizant in treatment of RLS

FDA issues Complete Response Letter for Horizant in treatment of RLS

Research findings highlight the vital need for better secondary stroke prevention

Research findings highlight the vital need for better secondary stroke prevention

Memory loss or decline in thinking abilities may indicate higher risk of stroke

Memory loss or decline in thinking abilities may indicate higher risk of stroke

Reducing DA dosage causes acute withdrawal symptoms in Parkinson's patients

Reducing DA dosage causes acute withdrawal symptoms in Parkinson's patients

Erectile dysfunction linked to RLS in older men

Erectile dysfunction linked to RLS in older men

Study: Men who do moderate-to-heavy intensity exercise are less likely to have stroke

Study: Men who do moderate-to-heavy intensity exercise are less likely to have stroke

Astellas Pharma and XenoPort submit NDA in Japan for PMDA approval

Astellas Pharma and XenoPort submit NDA in Japan for PMDA approval

Children with autism may have lower quality handwriting, says study

Children with autism may have lower quality handwriting, says study

FDA extends review date of New Drug Application for GSK1838262/XP13512

FDA extends review date of New Drug Application for GSK1838262/XP13512

Neurogen announces financial results for the third quarter of 2009

Neurogen announces financial results for the third quarter of 2009

Caucasian women may suffer from RLS up to four times more than African-American women

Caucasian women may suffer from RLS up to four times more than African-American women

Study: High protein levels are associated with heart attack and not stroke

Study: High protein levels are associated with heart attack and not stroke

GSK reports positive Phase II results from trial evaluating GSK1838262 for post-herpetic neuralgia

GSK reports positive Phase II results from trial evaluating GSK1838262 for post-herpetic neuralgia

Results from Phase IIb clinical trial evaluating the safety and efficacy of GSK1838262/XP13512 announced

Results from Phase IIb clinical trial evaluating the safety and efficacy of GSK1838262/XP13512 announced

Gabapentin improves sleep quality in menopausal women

Gabapentin improves sleep quality in menopausal women

LTS LOHMANN Therapie-Systeme celebrates 25th anniversary

LTS LOHMANN Therapie-Systeme celebrates 25th anniversary

Neurogen stockholders to receive $11 million in Ligand Pharmaceuticals common stock as part of acquisition deal

Neurogen stockholders to receive $11 million in Ligand Pharmaceuticals common stock as part of acquisition deal

ADHD genes found - missing DNA segments may suggest future drug targets

ADHD genes found - missing DNA segments may suggest future drug targets