Retinal tissue may degenerate for a number of reasons. Among them are: artery or vein occlusion, diabetic retinopathy, R.L.F./R.O.P. or disease (usually hereditary). Retinitis pigmentosa, retinoschisis, lattic degeneration, and macular degeneration are characterized by progressive types of retinal degeneration.
Millions of Americans are progressively losing their sight as cells in their eyes deteriorate, but a new therapy developed by researchers at the University of California, Berkeley, could help prolong useful vision and delay total blindness.
How is a healthy retina cell like a tumor cell? It hijacks an energy-producing chemical reaction to churn out molecular building blocks. When tumor cells do it, they use the building blocks to make cancer grow and spread. But when retina cells do it, they renew photoreceptor membranes that keep our vision sharp.
Retinal dystrophies such as Age-related macular degeneration (AMD) are a major cause of vision loss in aging populations. National Eye Institute (NEI) estimates that the prevalence of advanced AMD will grow to nearly 3 million by 2020.
A signaling pathway controlled by transforming growth factor beta (TGF-beta) could be involved in the progression of age-related macular degeneration.
Calcified nodules in the retina are associated with progression to late stages of age-related macular degeneration.
A new form of therapy may halt or even reverse a form of progressive vision loss that, until now, has inevitably led to blindness.
Sheets of fetal cells integrate into the retina and generate nearly normal visual activity in the brains of blind rats, reports new research published in JNeurosci.
Glaucoma, a disease that afflicts nearly 70 million people worldwide, is something of a mystery despite its prevalence. Little is known about the origins of the disease, which damages the retina and optic nerve and can lead to blindness.
Retinitis pigmentosa is a rare and hereditary neurodegenerative disease which causes vision loss due to the death of photoreceptors in the retina, and for which there is currently no treatment.
OHSU scientists have discovered a naturally occurring disease in monkeys that mimics a deadly childhood neurodegenerative disorder in people - a finding that holds promise for developing new gene therapies to treat Batten disease.
A new therapeutic approach may one day delay neurodegeneration typical of a disease called mucopolysaccharidoses IIIB. Neurodegeneration in this condition results from the abnormal accumulation of essential cellular molecules called mucopolysaccharides.
Researchers affiliated with the Kawasaki INnovation Gateway at SKYFRONT have developed new mouse models of retinal degeneration that enable transplantation of retinal sheets derived from human embryonic stem cells.
Researchers from Columbia University have developed a new technique for the powerful gene editing tool CRISPR to restore retinal function in mice afflicted by a degenerative retinal disease, retinitis pigmentosa.
Houston Methodist researchers developed a new lab-on-a-chip technology that could quickly screen possible drugs to repair damaged neuron and retinal connections, like what is seen in people with macular degeneration or who've had too much exposure to the glare of electronic screens.
More than 2 million people worldwide live with inherited and untreatable retinal conditions, including retinitis pigmentosa, which slowly erodes vision.
Duke Researchers have pinpointed a new therapeutic target for macular degeneration, an eye disease that affects over 10 million Americans and is the leading cause of blindness in adults over 60.
A new study found that prolonged exposure to dim light may alter the brain's structure, and impair an individual’s ability to remember and learn.
Understanding how dietary essential fatty acids work may lead to effective treatments for diseases and conditions such as stroke, Alzheimer's disease, age-related macular degeneration, Parkinson's disease and other retinal and neurodegenerative diseases.
Researchers at Johns Hopkins Medicine report evidence that zebrafishes' natural ability to regenerate their eyes' retinal tissue can be accelerated by controlling the fishes' immune systems.
The University of Illinois at Chicago College of Medicine will launch a new center that will focus on understanding tissue regeneration and pioneering future developments in stem cell biology as a means to repair diseased organs and tissues.