Retinoic Acid News and Research

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Retinoic Acid is a nutrient that that body needs in small amounts to function and stay healthy. All-trans retinoic acid is made in the body from vitamin A and helps cells to grow and develop, especially in the embryo. A form of all-trans retinoic acid made in the laboratory is put on the skin to treat conditions such as acne and is taken by mouth to treat acute promyelocytic leukemia (a fast-growing cancer in which there are too many immature blood-forming cells in the blood and bone marrow). All-trans retinoic acid is being studied in the prevention and treatment of other types of cancer. Also called ATRA, retinoic acid, tretinoin, and vitamin A acid.

Review portrays clinical journey of messenger RNA vaccines and mRNA-based therapies

Researchers reviewed messenger ribonucleic acid (mRNA) technology and highlighted its clinical applications.

11 May 2022

Scientists explore immunopathology of COVID-19

Researchers explored the interactions between severe acute respiratory syndrome coronavirus 2 and the host in the development of COVID-19.

6 May 2022

Artificial circular RNAs found to bypass cellular antiviral responses

Researchers produced artificial circular ribonucleic acid sponges in a permuted intron-exon system and showed that these did not activate innate immunity.

29 Apr 2022

Role of cGAS-STING in SARS-CoV-2 infection

A new study analyzes the activation of cGAS and STING can induce a type I IFN response due to SARS-CoV-2 infection.

15 Apr 2022

Scientists find critical role for Hippo signaling pathway in COVID-19 pathogenesis

A recent article posted to the bioRxiv* preprint server illustrated that the activation of the Hippo signaling pathway upon severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection aids the host antiviral response.

11 Apr 2022

Antiviral functions of interferon regulatory factors during human coronavirus infection

Researchers assessed the roles of the interferon regulatory factors: IRF1, IRF3, and IRF7 in infections by human coronaviruses.

30 Mar 2022

Non-hormonal male contraceptive effectively prevents pregnancy in mice

Women have many choices for birth control, ranging from pills to patches to intrauterine devices, and partly as a result, they bear most of the burden of preventing pregnancy.

24 Mar 2022

TTUHSC secures $1.87 million grant to investigate the impact of vitamin A depletion on Alzheimer’s disease

Ongoing research suggests that an accumulation of toxic reactive oxygen species (ROS) in the area of the brain known as the hippocampal dentate gyrus may begin early on in patients with Alzheimer's disease.

21 Mar 2022

Study evaluates efficacy of isotretinoin in improving COVID-19 outcomes

Researchers evaluated the effectiveness of isotretinoin (13-cis retinoic acid) in improving COVID-19 outcomes.

14 Mar 2022

Effect of COVID-19 mRNA vaccine on in vitro glial cells of the brain studied by Raman spectroscopy and imaging

Researchers studied how the mRNA-based BNT162b2 COVID-19 vaccine altered the biochemical composition of glial and glioma brain cells in vitro.

8 Mar 2022

The need for a holistic and unbiased approach to develop a more universal vaccine for coronaviruses

Researchers emphasized the need to take on a holistic and unbiased approach to develop a universal vaccine for coronaviruses, including SARS-CoV-2, which is a biomedical priority during the ongoing COVID-19 pandemic.

28 Feb 2022

Innate immune processes involved in SARS-CoV-2 recognition and resultant inflammation

A new article reviewed the innate immune detection and signaling pathways that the host uses against SARS-CoV-2.

7 Feb 2022

Potential therapy candidates for patients infected with the SARS-CoV-2 Omicron variant

Researcher discusses several promising therapeutic candidates that have been proposed for the treatment of patients infected with the Omicron variant.

28 Jan 2022

Discovery of a broad-spectrum antiviral activity in self-assembling immunostimulatory duplex RNAs

A new study, published on the bioRxiv* preprint server, has discovered a class of new immunostimulatory RNAs while studying influenza infection-associated host genes in human lung epithelial cells using small interfering RNAs (siRNAs). Scientists revealed that these short duplex RNAs could induce type I and type III interferons (IFN-I/III) in a wide variety of cells.

23 Nov 2021

Retinoic Acid News and Research

Further Reading

Review portrays clinical journey of messenger RNA vaccines and mRNA-based therapies

Scientists explore immunopathology of COVID-19

Artificial circular RNAs found to bypass cellular antiviral responses

Role of cGAS-STING in SARS-CoV-2 infection

Scientists find critical role for Hippo signaling pathway in COVID-19 pathogenesis

Antiviral functions of interferon regulatory factors during human coronavirus infection

Non-hormonal male contraceptive effectively prevents pregnancy in mice

TTUHSC secures $1.87 million grant to investigate the impact of vitamin A depletion on Alzheimer’s disease

Study evaluates efficacy of isotretinoin in improving COVID-19 outcomes

Effect of COVID-19 mRNA vaccine on in vitro glial cells of the brain studied by Raman spectroscopy and imaging

The need for a holistic and unbiased approach to develop a more universal vaccine for coronaviruses

Innate immune processes involved in SARS-CoV-2 recognition and resultant inflammation

Potential therapy candidates for patients infected with the SARS-CoV-2 Omicron variant

Discovery of a broad-spectrum antiviral activity in self-assembling immunostimulatory duplex RNAs

Preexisting rhinovirus infection and IFN induction in epithelium of asthma patients decreases SARS-CoV-2 infection

New research finds disturbing lack of crucial blood cancer medication

Drug combination highly effective in children with standard- and high-risk acute promyelocytic leukemia

Yale researchers uncover how the brain takes shape during mid-pregnancy

Cardiotoxic effects of common chemotherapy drug could be prevented

Pinning down Pin1: Potential COVID-19 therapy

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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