Rheumatology News and Research

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Rheumatology is a sub-specialty in internal medicine and pediatrics, devoted to the diagnosis and therapy of rheumatic diseases. Rheumatologists mainly deal with clinical problems involving joints, soft tissues and allied conditions of connective tissues.

Study unlocks how cortisone activates the body’s natural “brakes” on inflammation

Cortisone and other related glucocorticoids are extremely effective at curbing excessive immune reactions.

10 Apr 2024

Enhancer-gene mapping with SCENT method offers insights into disease mechanisms

Genetic studies of diseases map segments of the genome driving disease. But to understand how those changes contribute to disease progression, it is important to understand how they may alter gene regulation of disease genes in cell populations assumed to be driving disease.

10 Apr 2024

New project aims to engineer live joints for osteoarthritis treatment

About 32.5 million people in the United States and 500 million globally suffer from the degenerative joint disease known as osteoarthritis (OA), according to the Centers for Disease Control.

26 Mar 2024

ANU scientists uncover gene mutation driving psoriasis and psoriatic arthritis

Scientists from The Australian National University (ANU) have discovered a gene mutation is responsible for causing psoriasis – a chronic inflammatory skin disease that causes patients to develop red, scaly and itchy patches across their body.

25 Mar 2024

Study highlights global fertility decline and its implications for the future

The world is approaching a low-fertility future. Although by 2100 more than 97% of countries and territories will have fertility rates below what is necessary to sustain population size over time, comparatively high fertility rates in numerous low-income countries, predominantly in western and eastern sub-Saharan Africa, will continue to drive population increases in these locations throughout the century.

21 Mar 2024

Gout not just for Victorians: 1 in 40 Brits have this extremely painful disease

If you thought gout was an outdated condition affecting portly, red-faced Victorians, think again.1 in 40 Brits now have this extremely painful disease, making it the UK’s most common form of inflammatory arthritis. Cases among people in their 20s and 30s have increased by 30%, and faster monitoring and treatment is needed, says a leading expert.

18 Mar 2024

Study reveals key mechanism of PD-1 function

Insights into the workings of an immune cell surface receptor, called PD-1, reveal how treatments that restrict its action can potentially be strengthened to improve their anticancer effect, a new study shows.

9 Mar 2024

Tryptophan digestion by gut microbiome spurs arthritis inflammation

A University of Colorado Department of Medicine faculty member says she and her colleagues have identified the means in which bacteria in the digestive system can break down tryptophan in the diet into an inflammatory chemical that primes the immune system towards arthritis.

7 Mar 2024

New study aims to reduce bias in AI health prediction models

Rapid advances in Artificial Intelligence (AI) have opened the way for the creation of a huge range of new healthcare tools, but to ensure that these tools do not exacerbate preexisting health inequities, researchers urge the use of more representative data in their development.

7 Mar 2024

Unlocking the secrets of T follicular helper cells for better treatment strategies

T follicular helper cells (Tfh) are essential for strong antibody-mediated reactions of our immune system during infections and vaccinations. However, if they get out of control, this can cause diseases such as autoimmunity, allergies or cancer.

1 Mar 2024

Calcium crystal deposits linked to worsening knee osteoarthritis, study finds

Knee osteoarthritis (OA) is the most common form of arthritis, affecting approximately 600 million people worldwide and 34 million people in the U.S.

28 Feb 2024

New blood biomarkers identified to predict cardiovascular risk in rheumatoid arthritis patients

Rheumatoid arthritis impacts approximately 2 million people in the United States and is associated with increased risk of cardiovascular disease.

28 Feb 2024

Targeting the Hippo signaling pathway to treat systemic sclerosis

Systemic sclerosis causes the skin to tighten and harden resulting in a potentially fatal autoimmune condition that is associated with lung fibrosis and kidney disease.

21 Feb 2024

NYU Langone Health receives $75 million gift to establish Julia Koch Family Ambulatory Care Center in Florida

NYU Langone Health today announced plans to open the Julia Koch Family Ambulatory Care Center in West Palm Beach, Florida, in 2026, made possible by a $75 million gift by the Julia Koch Family Foundation.

21 Feb 2024

World-first discovery offers potential cure for lupus

Australian researchers have worked out how to fix a defect that causes lupus, and hope their world-first discovery will offer effective long-term treatment.

6 Feb 2024

New points-to-consider in the diagnosis, treatment of systemic hyperinflammatory syndromes

Hemophagocytic lymphohistiocytosis (HLH) and macrophage activation syndrome (MAS) are life-threatening systemic hyperinflammatory syndromes.

5 Feb 2024

Study shows nuanced pregnancy outcomes for pregnant individuals with autoimmune disease

For many aspiring mothers with autoimmune disease, pregnancy can be daunting and full of unknowns. In some cases, those suffering from specific autoimmune conditions have chosen to forego pregnancy altogether due to concerns about their disease treatments and adverse pregnancy outcomes.

1 Feb 2024

Updated recommendations for management of people with hip and knee osteoarthritis

OA affects over 500 million people worldwide. The disease is age related, and usually starts to affect people in middle age.

29 Jan 2024

Oxford launches LEGACY03 trial to unravel age-related vaccine mysteries

Vaccines are the most effective way to prevent infectious diseases (NHS, 2023) however, people respond to them in different ways.

18 Jan 2024

A new test could save arthritis patients time, money, and pain. But will it be used?

Erinn Maury knew Remicade wasn't the right drug for Patti Schulte, a rheumatoid arthritis patient the physician saw at her Millersville, Maryland, practice. Schulte's swollen, painful joints hadn't responded to Enbrel or Humira, two drugs in the same class.

20 Dec 2023