Rheumatology News and Research

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Rheumatology is a sub-specialty in internal medicine and pediatrics, devoted to the diagnosis and therapy of rheumatic diseases. Rheumatologists mainly deal with clinical problems involving joints, soft tissues and allied conditions of connective tissues.

Normal BMI, regular exercise protect against musculoskeletal symptoms

Researchers at the Norwegian University of Science and Technology have found an association between the level of leisure time physical exercise and a future risk of developing fibromyalgia. The research team also identified BMI as an independent risk factor for fibromyalgia. Details of the study appear in the May 2010 issue of Arthritis Care & Research, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology.

29 Apr 2010

Multicenter NIH trial finds combination antibiotics effective against Chlamydia-induced reactive arthritis

Combination antibiotics effectively treat Chlamydia-induced reactive arthritis - a major step toward management, and possibly cure, of this disease, a federal multicenter clinical trial led by the University of South Florida College of Medicine found.

29 Apr 2010

Combination of antibiotics can cure Chlamydia-induced ReA: Study

Researchers from University of South Florida College of Medicine found a combination of antibiotics to be an effective treatment for Chlamydia-induced reactive arthritis, a major step forward in the management, and possibly cure, of this disease. Results of this study are published in the May issue of Arthritis & Rheumatism, a journal of the American College of Rheumatology.

29 Apr 2010

Positive results from interim analysis of ongoing Phase 2a study of BCX4208

BioCryst Pharmaceuticals, Inc. announced positive top-line results from a planned interim analysis of its ongoing Phase 2a, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of orally administered BCX4208 in patients with gout.

28 Apr 2010

Takeda settles with six defendants in generic ACTOS, ACTOplus met patent infringement lawsuit

Takeda Pharmaceutical Company Limited announced today that Takeda and its wholly owned subsidiary, Takeda Pharmaceuticals North America, Inc., have completed settlement agreements with six out of eight defendants in patent infringement litigation brought against these parties in response to their Abbreviated New Drug Applications for generic ACTOS® (pioglitazone HCl) and ACTOplus met® (pioglitazone HCl and metformin HCl). Takeda recently concluded litigation with the sixth settling defendant.

28 Apr 2010

University of Granada researcher designs reliable method to diagnose fibromyalgia

A researcher from the University of Granada has designed a reliable method that -combined with the diagnostic criteria of the American College of Reumathology- helps to diagnose fibromyalgia on the basis of patients' walk parameters, i.e. their gait.

28 Apr 2010

Takeda announces submission of azilsartan medoxomil NDA for hypertension to FDA

Takeda Pharmaceutical Company Limited (Takeda) announced today that Takeda Global Research & Development Center, Inc., U.S., submitted a New Drug Application (NDA) to the United States Food and Drug Administration (FDA) for azilsartan medoxomil (development code: TAK-491), an angiotensin II receptor blocker (ARB) under investigation for the treatment of hypertension. Discovered by Takeda, azilsartan medoxomil is designed to lower blood pressure by blocking the action of a vasopressor hormone, angiotensin II.

28 Apr 2010

Covidien introduces PENNSAID to the U.S. market

Covidien, a leading global provider of healthcare products, has introduced PENNSAID (diclofenac sodium topical solution) 1.5% w/w to the U.S. market. PENNSAID is the only FDA-approved topical non-steroidal anti-inflammatory drug in a vehicle solution containing dimethyl sulfoxide, a known penetrating agent. It is indicated for treatment of the signs and symptoms of osteoarthritis of the knee(s).

26 Apr 2010

As hip replacement steadily increasing, patients need to know the facts before procedure: Surgeons

On the golf course, in the garden, or at the shopping mall, most people want to stay active, regardless of age. As the number of Americans reaching their 60s grows daily, the demand for mobility-restoring procedures, such as hip replacement, is steadily increasing.

24 Apr 2010

Young gymnasts need proper amount of nutrition to keep their bodies healthy: HSS

Most elite gymnasts reach their peak at age 15 or 16, training 20 to 36 hours per week when a body's calorie needs are at its highest. But in a sport where aesthetics can influence scores, some athletes adopt restrictive eating habits to control their physique.

24 Apr 2010

Results of study comparing REMICADE to azathioprine for Crohn's disease published

Findings published today in The New England Journal of Medicine from a first-of-its-kind comparator trial evaluating the anti-tumor necrosis factor (TNF)-alpha biologic treatment REMICADE (infliximab) in the treatment of moderately to severely active Crohn's disease in patients who were naive to immunomodulator and biologic therapy, showed that a significantly greater proportion of patients receiving REMICADE achieved steroid-free remission and mucosal healing compared with patients receiving azathioprine.

16 Apr 2010

Data from Phase 2 clinical trials of Hematide/peginesatide presented at NKF Annual Meeting

Affymax, Inc. and Takeda Global Research & Development Center, Inc., U.S., today announced data from several post hoc analyses of Phase 2 clinical trials that evaluated Hematide/peginesatide in dialysis patients with anemia in chronic kidney disease. The data provide hypotheses for further investigation of this agent in anemia management in this patient population.

16 Apr 2010

FDA: Seven MDIs for treating asthma and COPD to be phased out

The U.S. Food and Drug Administration today announced, in accordance with longstanding U.S. obligations under the Montreal Protocol on Substances that Deplete the Ozone Layer, seven metered-dose inhalers (MDI) used to treat asthma and chronic obstructive pulmonary disease (COPD) will be gradually removed from the U.S. marketplace. These inhalers contain ozone-depleting chlorofluorocarbons (CFCs), which are propellants that move medication out of the inhaler and into the lungs of patients.

15 Apr 2010

2010 UCBeyond Scholarship Program launched to help students living with chronic illnesses

UCB Canada Inc. is proud to announce the launch of the 2010 UCBeyond Scholarship Program. During its four-year lifespan, the UCBeyond Scholarship has allocated almost 70 educational bursaries worth close to $350,000.00 CAN to students living with chronic illnesses such as rheumatoid arthritis, Crohn's disease and epilepsy.

15 Apr 2010

Perceptive Informatics expands medical imaging capabilities with enhanced reporting solution

Perceptive Informatics, a leading eClinical solutions provider and a subsidiary of PAREXEL International Corporation, today announced that it has expanded its leading medical imaging capabilities with an enhanced reporting solution.

From Parexel 13 Apr 2010

Study identifies pathway linked to rheumatoid arthritis

Investigators from Hospital for Special Surgery have identified a pathway involved in turning off inflammation that does not work properly in people with inflammatory arthritis. The finding, reported in the April 23 issue of the journal Immunity, could lead to the development of new therapeutic approaches to treating arthritis in the future.

13 Apr 2010

Women living in northeastern U.S. more likely to develop RA: Study

Women living in the northeastern United States are more likely to develop rheumatoid arthritis, suggesting a link between the autoimmune disease and vitamin D deficiency, says a new study led by a Boston University School of Public Health researcher.

8 Apr 2010

$Women unaware of risk of dangerous osteoporosis fractures$

Women unaware of risk of dangerous osteoporosis fractures

Only one in three Australian women diagnosed with osteoporosis are aware they are at higher risk of sustaining debilitating bone fractures, according to a landmark international study published with input from University of Sydney researchers.

7 Apr 2010

Mobile compression device effective in preventing blood clots after hip replacement surgery

A mobile compression device is as effective as medication at preventing the formation of blood clots after hip replacement surgery but provides greater patient safety, according to a study in the March issue of the Journal of Bone & Joint Surgery.

7 Apr 2010

NKF 2010 Spring Clinical Meeting: Multiple posters on Hematide/peginesatide to be presented

Affymax, Inc. and Takeda Pharmaceuticals Global Research & Development Center, Inc., U.S., today announced multiple posters on Hematide™/peginesatide have been accepted for presentation at the National Kidney Foundation (NKF) 2010 Spring Clinical Meeting taking place April 13-17, 2010 in Orlando, Florida. Hematide is an investigational agent for the treatment of anemia in chronic renal failure (also referred to as renal anemia).

31 Mar 2010

Rheumatology News and Research

Further Reading

Normal BMI, regular exercise protect against musculoskeletal symptoms

Multicenter NIH trial finds combination antibiotics effective against Chlamydia-induced reactive arthritis

Combination of antibiotics can cure Chlamydia-induced ReA: Study

Positive results from interim analysis of ongoing Phase 2a study of BCX4208

Takeda settles with six defendants in generic ACTOS, ACTOplus met patent infringement lawsuit

University of Granada researcher designs reliable method to diagnose fibromyalgia

Takeda announces submission of azilsartan medoxomil NDA for hypertension to FDA

Covidien introduces PENNSAID to the U.S. market

As hip replacement steadily increasing, patients need to know the facts before procedure: Surgeons

Young gymnasts need proper amount of nutrition to keep their bodies healthy: HSS

Results of study comparing REMICADE to azathioprine for Crohn's disease published

Data from Phase 2 clinical trials of Hematide/peginesatide presented at NKF Annual Meeting

FDA: Seven MDIs for treating asthma and COPD to be phased out

2010 UCBeyond Scholarship Program launched to help students living with chronic illnesses

Perceptive Informatics expands medical imaging capabilities with enhanced reporting solution

Study identifies pathway linked to rheumatoid arthritis

Women living in northeastern U.S. more likely to develop RA: Study

Women unaware of risk of dangerous osteoporosis fractures

Mobile compression device effective in preventing blood clots after hip replacement surgery

NKF 2010 Spring Clinical Meeting: Multiple posters on Hematide/peginesatide to be presented

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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