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Examining the cardiac pathology in fatal cases of yellow fever

The characteristics of yellow fever (YF)-related myocardial damage.

28 Sep 2023

Ramadan fasting reshapes gut microbiome

Scientists investigate the effects of Ramadan intermittent fasting on gut microbiota, revealing significant alterations at both the phylum and genus levels. The study suggests that dietary intake during fasting could play a key role in these microbiota changes.

27 Sep 2023

Medication and mutations: molnupiravir's impact on SARS-CoV-2 genomes

Researchers discovered molnupiravir-associated mutational signatures in SARS-CoV-2 genomes.

27 Sep 2023

Could baseline gut microbiota predict the immune responses elicited by COVID-19 vaccines?

Researchers characterized the gut microbiota composition associated with the durability of COVID-19 vaccine-induced immunity.

27 Sep 2023

Gene-silencer study could pave the way for novel cancer therapeutics

Deep inside our cells-;each one complete with an identical set of genes-;a molecular machine known as PRC2 plays a critical role in determining which cells become heart cells, versus brain or muscle or skin cells.

26 Sep 2023

Key player in ovarian cancer may have implications for PCOS

Researchers explore the involvement and altered expression of BBOX1-AS1 and microRNA-19b in polycystic ovary syndrome.

26 Sep 2023

Intranasal vaccine shows promise against COVID variants in hamsters

Intranasal mRNA-LNP vaccines show promise in Syrian golden hamsters, effectively reducing SARS-CoV-2 viral loads and lung pathology. The study suggests potential efficacy against new variants, setting the stage for future research in human applications.

25 Sep 2023

Kombucha tea shows promise in lowering blood sugar levels for type 2 diabetics

A recent clinical trial conducted at Georgetown University Hospital suggests that kombucha tea may hold potential as an anti-hyperglycemic agent, reducing fasting blood glucose levels in adult patients with type 2 diabetes. While the results are promising, further research with larger sample sizes is needed to solidify the health benefits of kombucha in managing diabetes.

25 Sep 2023

How are SARS-CoV-2 variants outsmarting our immune system and vaccines?

Researchers use multiomics analysis to understand how SARS-CoV-2 variants, including Alpha, Delta, and Omicron, modulate the host's cellular responses and adapt to evade human immunity. The study highlights the potential for targeted therapies against both adaptive and innate immune responses.

25 Sep 2023

Could CaMKK2 enzyme be the key to treating bipolar disorder?

Researchers explore the role of the CaMKK2 signaling pathway in bipolar disorder, suggesting it as a new treatment target. By targeting this enzyme, scientists aim to develop more effective therapies for bipolar symptoms and metabolic dysfunction.

24 Sep 2023

Social adversity and stress leave distinct signatures on mom and baby gut health

Researchers evaluate the effect of social disadvantages and psychological stressors on the gut microbiome of mothers and their infants.

24 Sep 2023

Exercise boosts immune defense in Lynch syndrome patients

Aerobic exercise, specifically cycling, shows promise in reducing inflammation and boosting immune responses in the colonic tissue of Lynch syndrome patients, a group at high risk for colorectal cancer. The study suggests that regular exercise may offer a preventive approach for this patient population, though further randomized trials are needed.

24 Sep 2023

VAX-seq: the future of mRNA vaccine analysis and quality assurance?

Researchers proposed a simplified approach for analyzing mRNA vaccines using long-read sequencing.

22 Sep 2023

Vaccine impact: BNT162b2 and pediatric COVID-19 ambulatory visits in kids under 5

The association between BNT162b2 vaccine and (COVID-19)-related ambulatory visits.

20 Sep 2023

Unlocking the secret soldiers: How dendritic cells could revolutionize cancer immunotherapy

A recent review in the journal Immunity delves into the crucial role of dendritic cells (DCs) in shaping T-cell responses in cancer, highlighting their importance in both priming anti-tumor immunity and in ongoing immune interactions within tumors. The findings underscore the potential of DCs as key targets for next-generation cancer immunotherapies.

18 Sep 2023

Single-cell screening of cerebral organoids to identify developmental defects in autism

Researchers develop CRISPR-human organoids-single-cell RNA sequencing system to identify developmental brain defects in autism.

18 Sep 2023

Mitochondrial GTP metabolism acts through mitochondrial dynamics factors to regulate reproductive aging

Reproductive aging in Caenorhabditis elegans is regulated through an interaction of the metabolism of mitochondrial guanosine-triphosphate.

18 Sep 2023

Polish gulls harbor new coronavirus strains, spotlighting avian role in viral evolution

Researchers in Poland have identified five strains of gammacoronaviruses and deltacoronaviruses in black-headed and common gulls, shedding new light on the diversity and evolutionary potential of these viruses. The study highlights the need for ongoing research into animal reservoirs of coronaviruses, as they pose a risk for zoonotic transmission to humans.

17 Sep 2023

How well do current vaccines hold up against new SARS-CoV-2 variants BA.2.86 and FLip?

The study explores the efficacy of three-dose monovalent or bivalent vaccinations in neutralizing newly emerged SARS-CoV-2 variants BA.2.86 and FLip. While BA.2.86 showed lower immune evasion abilities compared to recent XBB variants, it was less effectively neutralized by the monoclonal antibody S309, raising questions about vaccine efficacy against evolving strains.

17 Sep 2023

Impact of prior SARS-CoV-2 infection and mRNA vaccination on contagiousness and infection risk

The study finds that natural SARS-CoV-2 infection offers stronger immunity against the virus compared to mRNA vaccines. However, mRNA vaccines significantly reduce the infectiousness of individuals with COVID-19, playing a crucial role in limiting the virus's transmission.

14 Sep 2023

Ribonucleic Acid News and Research

Examining the cardiac pathology in fatal cases of yellow fever

Ramadan fasting reshapes gut microbiome

Medication and mutations: molnupiravir's impact on SARS-CoV-2 genomes

Could baseline gut microbiota predict the immune responses elicited by COVID-19 vaccines?

Gene-silencer study could pave the way for novel cancer therapeutics

Key player in ovarian cancer may have implications for PCOS

Intranasal vaccine shows promise against COVID variants in hamsters

Kombucha tea shows promise in lowering blood sugar levels for type 2 diabetics

How are SARS-CoV-2 variants outsmarting our immune system and vaccines?

Could CaMKK2 enzyme be the key to treating bipolar disorder?

Social adversity and stress leave distinct signatures on mom and baby gut health

Exercise boosts immune defense in Lynch syndrome patients

VAX-seq: the future of mRNA vaccine analysis and quality assurance?

Vaccine impact: BNT162b2 and pediatric COVID-19 ambulatory visits in kids under 5

Unlocking the secret soldiers: How dendritic cells could revolutionize cancer immunotherapy

Single-cell screening of cerebral organoids to identify developmental defects in autism

Mitochondrial GTP metabolism acts through mitochondrial dynamics factors to regulate reproductive aging

Polish gulls harbor new coronavirus strains, spotlighting avian role in viral evolution

How well do current vaccines hold up against new SARS-CoV-2 variants BA.2.86 and FLip?

Impact of prior SARS-CoV-2 infection and mRNA vaccination on contagiousness and infection risk

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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