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Revolutionary CAR T-cell therapy shows promise in reversing age-related metabolic dysfunction

study evaluates senolytic CAR T-cell therapy targeting uPAR-positive cells in aged mice, showing its effectiveness in mitigating age-related metabolic dysfunction and offering a potential long-lasting treatment for aging-associated conditions.

28 Jan 2024

Maternal COVID-19 vaccination equally benefits preterm and full-term babies

A study in JAMA Network Open reveals that maternal COVID-19 vaccination provides similar antibody levels in preterm and full-term infants' cord blood, with higher doses leading to increased antibodies.

24 Jan 2024

New workflow identifies shared cancer targets, advancing immunotherapy

Researchers developed the Splicing Neo Antigen Finder (SNAF) workflow, integrating deep learning to identify shared immunogenic neoantigens in cancers, offering new targets for cancer immunotherapy, particularly in melanoma and ovarian cancer.

23 Jan 2024

Persistent presence of SARS-CoV-2 RNA found in long COVID patients

Researchers conduct blood digital transcriptomics to determine the persistence of SARS-CoV-2 RNA in patients with long COVID-19.

23 Jan 2024

Lung cancer prediction using biomarkers based on bronchoalveolar fluid microbiomes

The lung microbiomes of patients with benign and malignant pulmonary diseases.

23 Jan 2024

Discovery of toxic and protective short RNAs associated with Alzheimer's disease and superior memory capacity

Researchers explored how Death Induced by Survival gene Elimination through the analysis of RNA-induced silencing complex-bound short RNAs in Alzheimer's disease models influences neuronal survival and correlates with neurotoxicity in AD.

22 Jan 2024

Sweetener 'Stevia' does not alter gut microbiota composition, confirms new study

The impact of 12 weeks of regular consumption of stevia, non-nutritive sweeteners (NNSs), on the human gut microbiota.

22 Jan 2024

Study shows Omicron variants evade immune system like predecessors, suggesting key evolutionary trait in SARS-CoV-2

Researchers compared SARS-CoV-2 Omicron variant of concern replication in human cell lines and primary airway cultures and measured host responses to infection.

19 Jan 2024

Study reveals intestinal helminth infection diminishes T cell response to COVID-19 mRNA vaccine

Study investigates the impact of helminth infection on COVID-19 mRNA vaccine efficacy, revealing that while antibody responses remain largely unaffected, T-cell responses are significantly impaired, particularly against Omicron variants.

17 Jan 2024

Comprehensive analysis of more than 2 million SARS-CoV-2 samples detects co-infections and intra-host recombination

Researchers evaluated the prevalence of co-infection and intra-host recombination in over 2 million global SARS-CoV-2 cases and developed strategies for accurate identification and analysis of recombinant strains.

17 Jan 2024

Study shows slight increase in Guillain-Barre syndrome risk with adenovirus COVID vaccines

Study investigates the link between COVID-19 vaccines and autoimmune/neurological diseases, focusing on Guillain-Barre syndrome (GBS) risks associated with adenovirus vector vaccines.

16 Jan 2024

New study shows how brain glucose affects fungal disease treatment

Metabolite-drug-fungal interactions in the fungal meningitis pathogen Cryptococcus neoformans.

16 Jan 2024

Study reveals key role of skin microbiome in aging and skin health

Microbial taxa related to skin aging.

16 Jan 2024

mRNA COVID-19 vaccines highly effective in preventing hospitalizations among adolescents in Nordic study

Study evaluated the effectiveness of mRNA COVID-19 vaccines (BNT162b2, mRNA-1273, and heterologous schedules) in preventing hospitalization among adolescents in Nordic countries, finding high protection rates of 73% to 86% at six months.

14 Jan 2024

Immune dysregulation in long COVID patients uncovered in new study

Sstudy reveals significant immune changes in long COVID patients, including altered T cell responses and systemic inflammation, using advanced 'omics' and serological assays.

14 Jan 2024

Bivalent COVID-19 vaccines show higher effectiveness against thromboembolic events

Study finds bivalent mRNA COVID-19 vaccines are more effective than monovalent vaccines in preventing thromboembolic events in older adults and those with end-stage renal disease.

14 Jan 2024

Study shows engineered antibodies significantly boost Omicron neutralization

Researchers engineered IgA antibodies from IgG monoclonals, enhancing neutralization against Omicron by up to 75-fold and offering protection in mice models.

10 Jan 2024

New algorithm proves to be a powerful tool for detection and identification of novel bacterial organisms

Researchers developed the NOVA algorithm to systematically analyze bacterial isolates unidentified using traditional methods such as matrix-assisted laser desorption ionization-time of flight mass spectrometry and partial 16S rRNA gene sequencing using whole genome sequencing.

10 Jan 2024

"TimeMachine" algorithm revolutionizes circadian rhythm analysis with single blood sample

"TimeMachine," an algorithm developed by U.S. researchers, accurately predicts circadian phase from a single blood sample using gene expression, offering a novel, efficient approach to understanding circadian rhythms and their impact on health.

9 Jan 2024

Regular exercise key to unlocking whole-body health benefits and reducing disease risk

Study in Cell Metabolism explores how chronic exercise induces tissue adaptations, enhancing cardiometabolic health and reducing disease risk.

8 Jan 2024

Ribonucleic Acid News and Research

Revolutionary CAR T-cell therapy shows promise in reversing age-related metabolic dysfunction

Maternal COVID-19 vaccination equally benefits preterm and full-term babies

New workflow identifies shared cancer targets, advancing immunotherapy

Persistent presence of SARS-CoV-2 RNA found in long COVID patients

Lung cancer prediction using biomarkers based on bronchoalveolar fluid microbiomes

Discovery of toxic and protective short RNAs associated with Alzheimer's disease and superior memory capacity

Sweetener 'Stevia' does not alter gut microbiota composition, confirms new study

Study shows Omicron variants evade immune system like predecessors, suggesting key evolutionary trait in SARS-CoV-2

Study reveals intestinal helminth infection diminishes T cell response to COVID-19 mRNA vaccine

Comprehensive analysis of more than 2 million SARS-CoV-2 samples detects co-infections and intra-host recombination

Study shows slight increase in Guillain-Barre syndrome risk with adenovirus COVID vaccines

New study shows how brain glucose affects fungal disease treatment

Study reveals key role of skin microbiome in aging and skin health

mRNA COVID-19 vaccines highly effective in preventing hospitalizations among adolescents in Nordic study

Immune dysregulation in long COVID patients uncovered in new study

Bivalent COVID-19 vaccines show higher effectiveness against thromboembolic events

Study shows engineered antibodies significantly boost Omicron neutralization

New algorithm proves to be a powerful tool for detection and identification of novel bacterial organisms

"TimeMachine" algorithm revolutionizes circadian rhythm analysis with single blood sample

Regular exercise key to unlocking whole-body health benefits and reducing disease risk

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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