Ribonucleic Acid News and Research

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New peptide library paves the way for targeting elusive cancer factor MYC

Researchers developed a second-generation NTB bicyclic peptide library, identifying NT-B2R, a peptide that effectively targets MYC, a key factor in most human cancers, demonstrating its potential in inhibiting MYC transcription activities and cancer cell proliferation.

8 Jan 2024

Revolutionary RNA-based switch offers new control over gene expression in mammalian cells

Researchers developed an RNA-based switch, the pA regulator system, to control gene expression in mammalian cells by modulating synthetic polyA signal cleavage, offering a novel approach for gene therapy applications.

4 Jan 2024

EZH2 inhibitors show promise in regenerating insulin-producing cells for type 1 diabetes treatment

Study explores the potential of EZH2 inhibitors GSK126 and Tazemetostat in stimulating β-cell regeneration from pancreatic ductal progenitor cells, offering a novel therapeutic approach for Type 1 Diabetes.

3 Jan 2024

Spicing up the fight: Saffron's powerful impact on prostate cancer revealed

Saffron-treated prostate cancer (PCa) cells.

3 Jan 2024

Are pan-coronavirus vaccines an achievable goal in providing broad protection against human coronaviruses?

The current achievements in the development of a pan-coronavirus vaccine.

3 Jan 2024

New Pfizer/BioNTech vaccine variant shows enhanced protection against COVID-19 hospitalization

Study demonstrates that the BNT162b2 SARS-CoV-2 XBB1.5 variant-modified vaccine significantly reduces the risk of COVID-19-related hospitalizations and ambulatory visits, outperforming previous vaccine versions in the face of evolving virus strains.

2 Jan 2024

Gut microbiota linked to social anxiety behaviors

Study reveals that gut microbiota from individuals with social anxiety disorder (SAD) can induce social fear behaviors in mice, suggesting a causal role of gut microbes in modulating behaviors relevant to SAD.

2 Jan 2024

Exploring the global health challenge of hepatitis D

Review explores the global impact of the hepatitis D virus (HDV) on public health, detailing its transmission, clinical course, diagnosis, and treatment options.

2 Jan 2024

How immune cells shape our earliest breaths

Study profiles the development of immune cells in human lungs during embryonic and fetal stages, revealing their influence on epithelial cell fate and lung development.

1 Jan 2024

Study deciphers how misfolded protein drives dopaminergic neuron loss in Parkinson's

A so-called pathological protein long associated with Parkinson's disease has been found in a new study to trigger cells to increase protein synthesis, an event that eventually kills the subset of brain cells that die off in this neurodegenerative condition.

20 Dec 2023

Breakthrough in Parkinson's research: Scientists identify protein synthesis pathway as culprit

19 Dec 2023

Mice with humanized immune systems test new cancer therapeutic approach that blindfolds immune cells to the body’s self-recognition system

Researchers investigated the anticancer effects of drugs targeting human tumor-associated macrophages (TAMs) in vivo. In humanized murine models, they tested the effectiveness of an antibody to human signal regulatory protein alpha (SIRPα) for cancer immunotherapy.

19 Dec 2023

Ribonucleic Acid News and Research

New peptide library paves the way for targeting elusive cancer factor MYC

Revolutionary RNA-based switch offers new control over gene expression in mammalian cells

EZH2 inhibitors show promise in regenerating insulin-producing cells for type 1 diabetes treatment

Spicing up the fight: Saffron's powerful impact on prostate cancer revealed

Are pan-coronavirus vaccines an achievable goal in providing broad protection against human coronaviruses?

New Pfizer/BioNTech vaccine variant shows enhanced protection against COVID-19 hospitalization

Gut microbiota linked to social anxiety behaviors

Exploring the global health challenge of hepatitis D

How immune cells shape our earliest breaths

Study deciphers how misfolded protein drives dopaminergic neuron loss in Parkinson's

Breakthrough in Parkinson's research: Scientists identify protein synthesis pathway as culprit

Mice with humanized immune systems test new cancer therapeutic approach that blindfolds immune cells to the body’s self-recognition system

Cinnamon extract shows promise in reducing obesity by inhibiting fat cell growth and boosting fat breakdown

Chia genome sequenced, revealing potential health benefits

Study suggests iron accumulation plays a central role in senescence and fibrosis

Fetal hormone GDF15 linked to nausea and vomiting in pregnancy

Researchers report progress in the search for more accurate blood markers for acute kidney injury

Organoid study opens new avenues in pulmonary neuroendocrine cancer therapy

New optimized vaccine approach targets Hepatitis C virus variability

Immunoregulatory nanomedicines for the prevention and treatment of respiratory diseases

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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