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USP22 crucial for type III interferon signaling and SARS-CoV-2 infection

In a recent study posted to the bioRxiv* pre-print server, a team of researchers demonstrated that ubiquitin-specific peptidase 22 (USP22) is a crucial regulator of basal interferon (IFN) signaling in native human intestinal epithelial cells (hIECs).

7 Feb 2022

Scientists reveal how droplets of transcription factors collectively read DNA regions to switch on genes

Life starts with one cell. When an organism develops, dividing cells specialize to form the variety of tissues and organs that build up the adult body, while keeping the same genetic material – contained in our DNA.

6 Feb 2022

Detection of SARS-CoV-2 Delta variant infection in a domestic cat

The first published case describing the Delta variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a domestic cat in the United States highlights the realistic scenario of spillover infections with emerging viral variants that threaten human and animal health.

6 Feb 2022

Booster dose of Pfizer-BioNTech COVID vaccine protects elderly against Omicron

Researchers discuss the impact of mRNA booster immunization on the neutralizing activity against the SARS-CoV-2 Omicron variant in the elderly.

6 Feb 2022

Memory B cells found to potently neutralize SARS-CoV-2 Omicron variant

A team of researchers recently captured memory B cells from a cohort of SARS-CoV-2 convalescent or mRNA-vaccinated individuals to study the evolution of B cell-mediated antibody responses to the N-terminal domain in humans.

4 Feb 2022

Researchers suggest that visible blue light is a safe and variant-agnostic therapy against SARS-CoV-2

In a new study, researchers showed that 425 nm blue light can inactivate all major SARS CoV 2 variants.

4 Feb 2022

Relationship between SARS-CoV-2 neurotropism and Alzheimer's disease

In a new study, researchers evaluated the neurotropism of SARS-CoV-2 and its impact on COVID-19 patients with and without neurological disorders like Alzheimer's disease.

3 Feb 2022

Protocol for a systematic review to evaluate the role of viral cultures for assessing airborne transmission of SARS-CoV-2

Researchers presented the protocol for a systematic review assessing viral cultures for airborne transmission of SARS-CoV-2.

3 Feb 2022

Evaluating vaccine effectiveness and determining differences across demographic and clinical risk factors of COVID-19

Researchers assessed the effectiveness of COVID-19 vaccines against the manifestations of SARS-CoV-2 symptoms across different cohorts.

3 Feb 2022

Study results strongly support COVID mRNA vaccine boosters for nursing home residents

Researchers evaluate the vaccine effectiveness of mRNA booster dose in nursing home residents who completed the primary series of mRNA vaccination.

2 Feb 2022

Nanoparticle vaccine effective against eight SARS-CoV-2 variants in non-human primates

Researchers demonstrate that SARS-CoV-2 RBD-based nanoparticle vaccine induces neutralizing antibodies against SARS-CoV-2 variants.

2 Feb 2022

Booster dose of Covaxin vaccine candidate neutralizes Omicron and Delta variants

Researchers evaluate the neutralization potential of sera samples from subjects boosted with the Covaxin against the SARS-CoV-2 Omicron variant.

2 Feb 2022

Rapid antigen test for SARS-CoV-2 shows lower sensitivity

In a new study, researchers assessed a rapid antigen (Ag) test for SARS-CoV-2.

2 Feb 2022

Representative structures of SARS-CoV-2 and development of therapeutic agents for targeting these proteins

Researchers from China summarized the representative structures of SARS-CoV-2 proteins and discussed the development of novel therapeutic agents for targeting these proteins to treat and prevent COVID-19.

2 Feb 2022

Study reveals pet hamsters can acquire SARS-CoV-2 infection in real-life settings and transmit the virus back to humans

Researchers investigated the transmission of the SARS-CoV-2 Delta VOC from infected hamsters to humans.

2 Feb 2022

Study proposes Omicron variant may be derived from recombination of two early SARS-CoV-2 PANGO lineages

A recent study showed that the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Omicron variant is a chimera of two earlier PANGO lineages of SARS-CoV-2.

2 Feb 2022

Study demonstrates substantial immune response in individuals infected with SARS-CoV-2 Omicron variant

Researchers analyze neutralizing antibodies against the SARS-CoV-2 VOCs with the sera of vaccinated individuals infected with the Omicron variant.

1 Feb 2022

Developing post-vaccination SARS-CoV-2 standard reference sera

A new study reports the generation of reference sera reagents that were obtained from subjects vaccinated with one of four COVID-19 vaccines.

1 Feb 2022

Study: COVID-19 infections tend to be milder in fully vaccinated patients

The clinical and imaging characteristics of COVID-19 breakthrough infections in fully vaccinated patients tend to be milder than those of partially vaccinated or unvaccinated patients, according to a new multicenter study published in the journal Radiology.

1 Feb 2022

SARS-CoV-2 entry at the cell surface facilitated by trypsin

Exogenous trypsin treatment boosts SARS-CoV-2 infection in Vero E6 cells and promotes viral multiplication in cultured cells.

1 Feb 2022

Ribonucleic Acid News and Research

USP22 crucial for type III interferon signaling and SARS-CoV-2 infection

Scientists reveal how droplets of transcription factors collectively read DNA regions to switch on genes

Detection of SARS-CoV-2 Delta variant infection in a domestic cat

Booster dose of Pfizer-BioNTech COVID vaccine protects elderly against Omicron

Memory B cells found to potently neutralize SARS-CoV-2 Omicron variant

Researchers suggest that visible blue light is a safe and variant-agnostic therapy against SARS-CoV-2

Relationship between SARS-CoV-2 neurotropism and Alzheimer's disease

Protocol for a systematic review to evaluate the role of viral cultures for assessing airborne transmission of SARS-CoV-2

Evaluating vaccine effectiveness and determining differences across demographic and clinical risk factors of COVID-19

Study results strongly support COVID mRNA vaccine boosters for nursing home residents

Nanoparticle vaccine effective against eight SARS-CoV-2 variants in non-human primates

Booster dose of Covaxin vaccine candidate neutralizes Omicron and Delta variants

Rapid antigen test for SARS-CoV-2 shows lower sensitivity

Representative structures of SARS-CoV-2 and development of therapeutic agents for targeting these proteins

Study reveals pet hamsters can acquire SARS-CoV-2 infection in real-life settings and transmit the virus back to humans

Study proposes Omicron variant may be derived from recombination of two early SARS-CoV-2 PANGO lineages

Study demonstrates substantial immune response in individuals infected with SARS-CoV-2 Omicron variant

Developing post-vaccination SARS-CoV-2 standard reference sera

Study: COVID-19 infections tend to be milder in fully vaccinated patients

SARS-CoV-2 entry at the cell surface facilitated by trypsin

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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