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Colchicine holds promise to reduce the risk of severe COVID-19

A recent article, published in Rheumatology and Therapy, reviews the potent evidence of colchicine against the SARS-CoV-2 infection.

7 Feb 2022

Investigating the immunology of COVID-19 infected children

Researchers published a new study that focused on the key principles of developmental immunology associated with immunobiology and the clinical impacts of COVID-19 infections in children and adults.

7 Feb 2022

Omicron sequences containing Delta mutation detected during SARS-CoV-2 genomic surveillance

This research letter published in Emerging Infectious Diseases warns scientists to interpret unusual mutations with caution.

7 Feb 2022

COVID-19 patients are at high risk of developing heart problems up to a year after infection

An analysis of federal health data indicates that people who have had COVID-19 are at increased risk of developing cardiovascular complications within the first month to a year after infection, according to researchers at Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care System.

7 Feb 2022

Evolutionary history of ACE2 binding across a diverse range of sarbecoviruses and ACE2 orthologs

Researchers have been investigating sarbecovirus lineages and the ability of those lineages to evolve the ability to bind ACE2.

7 Feb 2022

Study explores omicron-reactive T- and B- cell responses in COVID-19 vaccine recipients

A new study analyzes neutralizing antibodies and T-cell responses targeting the SARS-CoV-2 D614G, as well as some variants of concern.

7 Feb 2022

Study links COVID-19 inflammatory manifestations in brain lysates to Alzheimer’s Disease markers

In a new study, researchers investigated a link between the body’s inflammatory response to SARS-CoV-2 infection within the neuropathological pathways and tau hyperphosphorylation.

7 Feb 2022

Evaluating delayed vaccination schedules for protection against SARS-CoV-2

Researchers conducted an observational study to compare the humoral and cellular responses in health care workers who had received two doses of the Pfizer-BioNTech vaccine at standard (3 to 6 weeks) and delayed (8 to 16 week) intervals.

7 Feb 2022

Innate immune processes involved in SARS-CoV-2 recognition and resultant inflammation

A new article reviewed the innate immune detection and signaling pathways that the host uses against SARS-CoV-2.

7 Feb 2022

Study investigates if prior SARS-CoV-2 infection increases sensitivity to toxin that induces parkinsonism

A recent study explored whether individuals who have recovered from mild to moderate or severe COVID-19 may have an increased risk for developing Parkinson’s disease in the future.

7 Feb 2022

Cerebrovascular impairment persists months after severe acute COVID-19, UK study

Researchers in the United Kingdom have conducted an observational cohort study on hospitalized patients and have found that the degree of severity of acute coronavirus disease 2019 (COVID-19) predicts the occurrence of chronic cerebrovascular impairment. The study further suggests that the levels of cerebrovascular impairment are associated with worse cognitive, mental, and physical well-being.

7 Feb 2022

USP22 crucial for type III interferon signaling and SARS-CoV-2 infection

In a recent study posted to the bioRxiv* pre-print server, a team of researchers demonstrated that ubiquitin-specific peptidase 22 (USP22) is a crucial regulator of basal interferon (IFN) signaling in native human intestinal epithelial cells (hIECs).

7 Feb 2022

Study looks at rapid antigen vs. PCR tests in the emergency department triage

In a recent study posted to the Lancet preprint* server, researchers assessed the utility of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) rapid antigen testing (RAT) for patient triage in the hospital emergency department (ED).

7 Feb 2022

Booster vaccines found to augment T-cell responses to SARS-CoV-2 Omicron

In a recent study published in the latest issue of the journal Cell, a team of researchers evaluated T-cell reactivity to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant's spike (S) and non-spike proteins.

6 Feb 2022

Sentinel cards found to be effective for indoor SARS-CoV-2 monitoring

In a recent study posted to the bioRxiv* preprint server, a team of researchers used sentinel cards for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) monitoring in schools where individual-level sampling is tedious due to privacy or compliance reasons and higher cost.

6 Feb 2022

Vaccine-induced immunity and prior infection effective in reducing COVID severity in reinfections

A recent study posted to the Research Square* preprint server and under consideration for inclusion in the journal Scientific Reports assessed the epidemiology of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) reinfections.

6 Feb 2022

Northwestern researchers study COVID-19 mechanisms, infection patterns and impact on gender minorities

Northwestern Medicine investigators continue to study the COVID-19 pandemic, from the biological mechanisms of disease and infection patterns to the pandemic's impact on women and sexual and gender minorities.

6 Feb 2022

Researchers discover a new function of anti-HIV-1 antibodies

Teams at the Institut Pasteur, CNRS, Vaccine Research Institute (VRI) and Université de Paris have discovered a new function of anti-HIV-1 antibodies by applying cutting-edge microscopy techniques to in vitro viral cultures.

6 Feb 2022

A novel approach to predict mutations within the SARS-CoV-2 spike

A study posted recently to the bioRxiv* preprint server demonstrated that the emergence of new spike variants of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) can be predicted.

6 Feb 2022

Detection of SARS-CoV-2 Delta variant infection in a domestic cat

The first published case describing the Delta variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a domestic cat in the United States highlights the realistic scenario of spillover infections with emerging viral variants that threaten human and animal health.

6 Feb 2022

SARS News and Research

Colchicine holds promise to reduce the risk of severe COVID-19

Investigating the immunology of COVID-19 infected children

Omicron sequences containing Delta mutation detected during SARS-CoV-2 genomic surveillance

COVID-19 patients are at high risk of developing heart problems up to a year after infection

Evolutionary history of ACE2 binding across a diverse range of sarbecoviruses and ACE2 orthologs

Study explores omicron-reactive T- and B- cell responses in COVID-19 vaccine recipients

Study links COVID-19 inflammatory manifestations in brain lysates to Alzheimer’s Disease markers

Evaluating delayed vaccination schedules for protection against SARS-CoV-2

Innate immune processes involved in SARS-CoV-2 recognition and resultant inflammation

Study investigates if prior SARS-CoV-2 infection increases sensitivity to toxin that induces parkinsonism

Cerebrovascular impairment persists months after severe acute COVID-19, UK study

USP22 crucial for type III interferon signaling and SARS-CoV-2 infection

Study looks at rapid antigen vs. PCR tests in the emergency department triage

Booster vaccines found to augment T-cell responses to SARS-CoV-2 Omicron

Sentinel cards found to be effective for indoor SARS-CoV-2 monitoring

Vaccine-induced immunity and prior infection effective in reducing COVID severity in reinfections

Northwestern researchers study COVID-19 mechanisms, infection patterns and impact on gender minorities

Researchers discover a new function of anti-HIV-1 antibodies

A novel approach to predict mutations within the SARS-CoV-2 spike

Detection of SARS-CoV-2 Delta variant infection in a domestic cat

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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