Saccharomyces Cerevisiae News and Research

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Scientists unravel how cells unfold proteins

A happy cell is a balanced cell, but for every stupendously twisted protein it creates, it must tear the old ones asunder. That means untangling a convoluted pretzel-like mass for recycling. Cdc48 plays a critical role in unraveling the spent proteins.

29 Jun 2019

Insights into parasitic yeast species could lead to new strategies for controlling yeast pathogens

Insights into the genes and proteins involved in the predatory behavior of a parasitic yeast species could lead to new strategies for controlling yeast pathogens, according to a study published May 9 in the open-access journal PLOS Pathogens by Jürgen Wendland of the Carlsberg Research Laboratory in Denmark and Vrije Universiteit Brussel in Belgium, and colleagues.

10 May 2019

Fractals can help describe how cancer spreads in the body and the right tools to stop it

What can seashells, lightning and the coastline of Britain teach us about new drugs for cancer?

7 Dec 2018

Study: Atg2 tethers pre-autophagosomal membrane to endoplasmic reticulum during autophagosome formation

Postdoctoral Researcher Tetsuya Kotani, Associate Professor Hitoshi Nakatogawa, Honorary Professor Yoshinori Ohsumi and colleagues at Tokyo Institute of Technology have analyzed the Atg protein Atg2, whose function had been completely unknown, and have discovered that Atg2 tethers the pre-autophagosomal membrane to the endoplasmic reticulum during autophagosome formation.

23 Oct 2018

Scientists develop new method to speed up genome evolution of baker's yeast

Scientists have created a new way of speeding up the genome evolution of baker's yeast Saccharomyces cerevisiae, the same yeast people use for bread and beer production, to develop a synthetic yeast strain that can be transformed on demand for use in various industrial applications.

26 May 2018

CRISPR-Cas9-based strategy allows researchers to precisely alter hundreds of different genes

Geneticists have been using model organisms ranging from the house mouse to the single-cell bakers' yeast, Saccharomyces cerevisiae, to study basic biological processes that regulate human development and physiology, and that can be compromised in various diseases.

22 May 2018

Researchers harness the precision of CRISPR to knock out single genes in yeast

Researchers have used CRISPR-Cas9 to develop a technology that can precisely target any gene in the yeast species Saccharomyces cerevisiae.

8 May 2018

Brazilian researchers identify genes linked to melanoma progression

When researchers at the University of São Paulo in Brazil treated human melanoma cell lines with a synthetic compound similar to curcumin, one of the pigments that give turmeric its orange color, they identified genes with altered expression in potentially invasive tumors and malignant cells resistant to chemotherapy.

6 Dec 2017

Protein that regulates expression of many genes increases lifespan of baker's yeast

To understand and control aging is the aspiration of many scientists. Researchers at the Biozentrum of the University of Basel have now discovered that the protein Gcn4 decreases protein synthesis and extends the life of yeast cells.

6 Sep 2017

Duke researchers map evolution of sex chromosomes in fungus linked to human disease

Biologically speaking, nearly every species on Earth has two opposite sexes, male and female. But with some fungi and other microbes, sex can be a lot more complicated.

11 Aug 2017

Research reveals role of Rrm3 protein in repair of breaks that occur during DNA replication

A research group from the University of Seville has revealed the role that the protein Rrm3 plays in the repair of breaks that occur during the replication of DNA, by using the yeast Saccharomyces cerevisiae as a model organism.

8 Jun 2017

Researchers invent promising paper-based technology to kill bacteria and sanitize surfaces

Imagine wearing clothes with layers of paper that protect you from dangerous bacteria. A Rutgers-led team has invented an inexpensive, effective way to kill bacteria and sanitize surfaces with devices made of paper.

2 May 2017

Probiotics may help treat yeast infections, bowel problems in men with schizophrenia

In a small pilot study of men with schizophrenia, researchers at Johns Hopkins Medicine and Sheppard Pratt Health System say they have evidence that adding probiotics -- microorganisms, such as bacteria found in yogurts -- to the patients' diets may help treat yeast infections and ease bowel problems.

5 Apr 2017

Researchers unravel protein dosage compensation mechanism in genes

Researchers at Okayama University report in PLOS Genetics which genes from the yeast genome exhibit dosage compensation — the ability to temper protein production when the corresponding encoding gene’s copy number increases.

16 Mar 2017

Researchers complete design phase for fully synthetic yeast genome

Working as part of an international research consortium, a multidisciplinary team at The Johns Hopkins University has completed the design phase for a fully synthetic yeast genome.

10 Mar 2017

Mice study shows role of yeast in aggravating IBD symptoms

During the past decade, the gut has experienced a renaissance as investigations focus on the role of the microbiome on human health.

8 Mar 2017

Enzyme identified in baker's yeast can efficiently annihilate leukemia cells

An enzyme identified in Saccharomyces cerevisiae, commonly known as brewer's or baker's yeast, has passed in vitro trials, demonstrating its capacity to kill acute lymphoblastic leukemia (ALL) cells.

18 Jan 2017

Tufts scientists discover reason for incidence of genetic error that causes many disorders

Tufts University researchers have discovered a possible explanation for the occurrence of a genetic error that causes over a dozen neuromuscular and neurodegenerative disorders, including Huntington's disease, myotonic dystrophy and forms of spinocerebellar ataxia.

6 Dec 2016

Helpful protein can change genetic sequence of normal cells and make mutations that cause cancers

Washington State University researchers have determined how a protein that helps cells fight viruses can also cause genetic mutations that lead to cancer.

10 Feb 2016

Johns Hopkins researchers identify new therapy to treat lung cancer

A multidisciplinary team led by Johns Hopkins researcher Venu Raman, Ph.D., with notable contributions from Guus Bol, Farhad Vesuna and Phuoc Tran of Johns Hopkins, has identified a new therapy for lung cancer, the most common cancer worldwide. The therapy has been in development for six years and involves a first-in-class molecule designed by the team.

20 May 2015