Sarcoma News and Research

RSS

Scientists pinpoint protein that plays key role in synovial sarcoma tumors

Researchers have pinpointed a protein that plays a key role in a type of rare cancer often leading to tumours around joints and tendons, according to new findings in eLife.

27 Nov 2018

Research may pave way for development of potent weapons against cancer

Despite significant advances in cancer research, the disease continues to exact a devastating toll. Because cancer is a disease of the body's own cells, which mutate and develop under evolutionary pressure, conventional treatments like chemotherapy and radiation often leave behind a residue of resistant cells that go on to expand and wreak havoc.

27 Nov 2018

FDA grants accelerated approval to oncology drug for treatment of key genetic driver of cancer

The U.S. Food and Drug Administration today granted accelerated approval to Vitrakvi (larotrectinib), a treatment for adult and pediatric patients whose cancers have a specific genetic feature (biomarker).

27 Nov 2018

Rare Cancers Asia aims to improve patient care

Rare cancers inherently make it difficult to collect data, build clinical expertise and treat affected patients - challenges which are best addressed through collaboration in international networks.

21 Nov 2018

Check your medical records for dangerous errors

When Liz Tidyman's elderly parents moved across the country to be closer to their children and grandchildren years ago, they carried their medical records with them in a couple of brown cardboard folders tied with string.

21 Nov 2018

Using smartphone confocal microscopes to stop cancer

Dongkyun "DK" Kang was in the shower a few years ago when inspiration struck, and he became interested in the idea of imaging human tissue in vivo, or on a living person, using a smartphone attached to a microscope.

20 Nov 2018

Potential new therapeutic approach developed for synovial sarcoma

Scientists have developed a potential new therapeutic approach for synovial sarcoma, one of the most common soft-tissue cancers in teenagers and young adults.

20 Nov 2018

Researchers discover possible path forward in preventing cancers tied to two viruses

Researchers from the University of Minnesota, the Howard Hughes Medical Institute, and the University of Toronto have discovered a possible path forward in preventing the development of cancers tied to two viruses, including the virus that causes infectious mononucleosis--more commonly known as mono or the "kissing disease"--that infects millions of people around the globe each year.

12 Nov 2018

Aggressive local therapy for stage IV lung cancer patients improves progression-free survival

Adding radiation therapy or surgery to systemic therapy for stage IV lung cancer patients whose cancer has spread to a limited number of sites can extend overall survival time significantly, according to new results from a multicenter, randomized, controlled phase II study. The findings were presented last week at the 60th Annual Meeting of the American Society for Radiation Oncology

30 Oct 2018

Researchers track where tetracycline antibiotics go in human cells

We know that antibiotics treat bacterial infections. We also know why they work. Tetracycline antibiotics, for example, stop bacteria from making protein. Like a boot on a wheel, the drugs bind to the bacterial cell's ribosome--where protein is made--and prevent it from working. Without protein, the bacteria weaken and die.

25 Oct 2018

Deciphera presents Phase 1 clinical results of DCC-2618 in patients with gastrointestinal stromal tumors

Deciphera Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company focused on addressing key mechanisms of tumor drug resistance, announced the presentation today of updated preliminary results from its ongoing Phase 1 clinical study of DCC-2618, the company's broad-spectrum KIT and PDGFRα inhibitor, in patients with gastrointestinal stromal tumors as a proffered paper presentation at the European Society of Medical Oncology 2018 Congress in Munich, Germany.

22 Oct 2018

Study highlights existence of barriers to early clinical trial access for adolescents and young adults

Young cancer patients at the crossroads of childhood and adulthood seem to be stuck in a treatment impasse. A study to be presented at the ESMO 2018 Congress in Munich, has highlighted the existence of barriers to the inclusion of 12 to 25-year-olds in both adult and pediatric early phase clinical trials, suggesting a need for more tailored approaches to give this patient population better access to therapeutic innovation.

22 Oct 2018

Phase 2 results on tazemetostat EZH2 inhibitor to be presented at ESMO 2018

Epizyme, Inc., a clinical-stage company developing novel epigenetic therapies, announced today that updated efficacy and safety data from the fully enrolled cohort of epithelioid sarcoma (ES) patients in its ongoing Phase 2 trial of tazemetostat will be presented in a poster discussion session at the European Society for Medical Oncology (ESMO) 2018 Congress to be held October 19-23 in Munich, Germany.

10 Oct 2018

Study: Sarcoma patients poorly informed about risk of interactions with anti-cancer drugs

Sarcoma patients show great openness to the use of complementary alternative medicines (CAMs) for supportive care, but they are poorly informed about safety issues and risk of interactions with anti-cancer drugs, a study to be presented at ESMO 2018 reported.

10 Oct 2018

Researchers successfully implant biomimetic hybrid prosthesis imitating bone structure

For the first time ever, a research team from the small innovative enterprise Biomimetix, implementing several NUST MISIS developments, has successfully implanted a biomimetic hybrid prosthesis imitating bone structure made from ultra-high molecular weight polyethylene and titanium alloy into a patient's femoral bone.

10 Oct 2018

New project identifies immune checkpoint inhibition as potential treatment for angiosarcomas

Angiosarcoma Project, a patient-partnered genomics study, identified immune checkpoint inhibition as a potential treatment option for patients with angiosarcomas of the head, face, neck, or scalp, according to data presented at the fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference.

1 Oct 2018

$Bacterial therapy shows early clinical efficacy in patients with treatment-refractory solid tumors$

Bacterial therapy shows early clinical efficacy in patients with treatment-refractory solid tumors

A phase I clinical trial investigating the use of bacterial Clostridium novyi-NT spores as an injectable monotherapy had manageable toxicities and showed early clinical efficacy in patients with treatment-refractory solid tumor malignancies, according to data presented at the Fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival, held Sept. 30-Oct. 3.

30 Sep 2018

FDA lifts partial clinical hold that paused enrollment of new patients in tazemetosta clinical trials

Epizyme, Inc., a clinical-stage company developing novel epigenetic therapies, today announced the U.S. Food and Drug Administration has lifted the partial clinical hold that had paused U.S.-based enrollment of new patients in its tazemetostat clinical trials.

24 Sep 2018

TINY cancer detection device shows promise as point-of-care detector of KSHV

Its name is an acronym used to convey its size, but researchers at Cornell Engineering and Weill Cornell Medicine are hoping their hand-held cancer detection device's impact in the developing world is anything but small.

21 Sep 2018

Immune checkpoint inhibition may be effective in treating HIV-associated Kaposi's sarcoma

Among a small cohort of patients with HIV-associated Kaposi's sarcoma treated with immune checkpoint inhibitors, more than 65 percent had partial or complete remission.

7 Sep 2018

Sarcoma News and Research

Scientists pinpoint protein that plays key role in synovial sarcoma tumors

Research may pave way for development of potent weapons against cancer

FDA grants accelerated approval to oncology drug for treatment of key genetic driver of cancer

Rare Cancers Asia aims to improve patient care

Check your medical records for dangerous errors

Using smartphone confocal microscopes to stop cancer

Potential new therapeutic approach developed for synovial sarcoma

Researchers discover possible path forward in preventing cancers tied to two viruses

Aggressive local therapy for stage IV lung cancer patients improves progression-free survival

Researchers track where tetracycline antibiotics go in human cells

Deciphera presents Phase 1 clinical results of DCC-2618 in patients with gastrointestinal stromal tumors

Study highlights existence of barriers to early clinical trial access for adolescents and young adults

Phase 2 results on tazemetostat EZH2 inhibitor to be presented at ESMO 2018

Study: Sarcoma patients poorly informed about risk of interactions with anti-cancer drugs

Researchers successfully implant biomimetic hybrid prosthesis imitating bone structure

New project identifies immune checkpoint inhibition as potential treatment for angiosarcomas

Bacterial therapy shows early clinical efficacy in patients with treatment-refractory solid tumors

FDA lifts partial clinical hold that paused enrollment of new patients in tazemetosta clinical trials

TINY cancer detection device shows promise as point-of-care detector of KSHV

Immune checkpoint inhibition may be effective in treating HIV-associated Kaposi's sarcoma

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

Latest News