Sarcoma News and Research

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MD Anderson researchers chosen for national effort to expand reach of cancer immunotherapy

A major national effort to expand the reach of cancer immunotherapy to benefit more patients will draw upon the expertise of a team of researchers at The University of Texas MD Anderson Cancer Center.

13 Oct 2017

Novel agents appear to halt growth and progression of Ewing sarcoma

When combined with an already FDA-approved chemotherapy, a novel agent developed by researchers at Georgetown Lombardi Comprehensive Cancer Center, appears to halt the ability of Ewing sarcoma to grow and progress.

4 Oct 2017

Diet and exercise have potential to improve chemotherapy effectiveness in pediatric cancer patients

Diet and exercise may improve treatment outcomes in pediatric cancer patients, according to a study at The University of Texas MD Anderson Children's Cancer Hospital.

21 Sep 2017

Researchers explore new combination approach to treat high-risk soft-tissue sarcomas

University of Maryland School of Medicine researchers are investigating a new approach to treat high-risk soft-tissue sarcomas by combining two immunotherapy drugs with radiation therapy to stimulate the immune system to destroy the main tumor as well as leftover microscopic cancer cells that may seed other tumors.

20 Sep 2017

Researchers create chimera virus that allows study of molecules to treat cancers

Researchers from Instituto de Medicina Molecular Lisboa have created a chimera virus that allows the study of molecules to treat cancers caused by human herpesvirus infection in mice models of disease.

18 Sep 2017

LSU Health New Orleans receives $10 million grant to support research on virus-induced cancers

The National Institute of General Medical Sciences has awarded LSU Health New Orleans a $10 million grant over five years to support new basic research studies advancing the development new diagnostic and therapeutic approaches for virus-induced cancers.

26 Aug 2017

Scientists develop new chimeric antibody to treat malignant cancers in dogs

Scientists have developed a new chimeric antibody that suppresses malignant cancers in dogs, showing promise for safe and effective treatment of intractable cancers.

26 Aug 2017

Research identifies new gene fusions and mutations linked to GIST tumors

Researchers at UC San Diego Moores Cancer Center, with colleagues from Memorial Sloan Kettering Cancer Center and Fox Chase Cancer Center, have determined that a specific region of the small bowel, called the duodenal-jejunal flexure or DJF, shows a high frequency of gastrointestinal stromal tumors (GISTs) with mutations of the NF1 gene

18 Aug 2017

FDA approves fixed dose combination chemotherapy for subtypes of AML that have poor survival outcomes

The U.S. Food and Drug Administration (FDA) yesterday approved Vyxeos - a fixed dose combination chemotherapy for the treatment of adults with two types of acute myeloid leukemia (AML). The types of AML that would be treated with Vyxeos include newly diagnosed therapy-related AML (t-AML) and AML with myelodysplasia-related changes (AML-MRC). Vyxeos is a fixed-combination of the chemotherapy drugs daunorubicin and cytarabine.

3 Aug 2017

Scientists propose therapeutic strategy to suppress formation of hereditary bony tumors

Patients with multiple hereditary exostoses (MHE)--a rare disease that causes the growth of multiple benign bone tumors -- have limited treatment options.

3 Aug 2017

UCLA research in sarcoma provides much-needed roadmap for personalizing therapies

Sarcoma is a rare and deadly form of cancer occurring in the bones and connective tissue that affects individuals of all ages.

3 Aug 2017

Existing drugs could help subgroup of patients with osteosarcoma, suggest scientists

A subgroup of patients with osteosarcoma - a form of bone cancer - could be helped by an existing drug, suggest scientists from the Wellcome Trust Sanger Institute and their collaborators at University College London Cancer Institute and the Royal National Orthopaedic Hospital NHS Trust.

23 Jun 2017

Study finds steady decline in severe health problems for childhood cancer survivors

Treatments for childhood cancer are often intense and carry the risk of lifelong health problems for survivors. An analysis of 23,600 childhood cancer survivors in the Childhood Cancer Survivor Study (CCSS), funded by the National Institutes of Health, found that the rate of severe health problems occurring five or more years after diagnosis has declined over time.

5 Jun 2017

New targeted oral therapy results in durable responses across many kinds of cancer

Scientists may have developed the first targeted, oral, tumor-type agnostic therapy - a cancer medicine that works comparably well across many kinds of cancer, regardless of patient age. In clinical trials of adults and children with 17 different types of advanced cancer, larotrectinib treatment resulted in responses in 76% of patients.

5 Jun 2017

Early study of experimental vaccine shows escalating immune response in patients with sarcoma

The critical component of an experimental vaccine led to an escalating immune response in patients with sarcoma, an indicator of its potential anti-cancer effects.

2 Jun 2017

Rice University scientists develop and evaluate analogs of potent cancer fighters

Rice University scientists have developed and evaluated analogs of potent anti-tumor agents known as epothilones using designs and methods that both improve their biological properties and simplify their manufacture.

31 May 2017

Researchers identify DNA repair deficiency in many types of solid tumors

A new investigation of more than 48,000 stored tumor samples finds evidence of a key deficiency in a repair mechanism designed to keep DNA from being mutated and causing cancer.

18 May 2017

CNIO researchers optimize new system capable of generating cellular model of Ewing sarcoma

A team from the Spanish National Cancer Research Centre (CNIO) has optimized a system capable of generating a cellular model of Ewing sarcoma.

10 May 2017

Use of videos can reduce need for anesthesia during radiotherapy for children with cancer

Children with cancer could be spared dozens of doses of general anesthesia by projecting a video directly onto the inside of a radiotherapy machine during treatment, according to research presented at the ESTRO 36 conference.

8 May 2017

Study suggests how existing and emerging immunotherapy treatments could be successful for sarcomas

Sarcomas- cancers of the connective tissues like muscles, joints, fat and bone -; come in dozens of subtypes. Clinical trial results have been mixed when treating these diverse tumors with immunotherapy, a targeted therapeutic strategy that has success in other cancers.

3 May 2017

Sarcoma News and Research

MD Anderson researchers chosen for national effort to expand reach of cancer immunotherapy

Novel agents appear to halt growth and progression of Ewing sarcoma

Diet and exercise have potential to improve chemotherapy effectiveness in pediatric cancer patients

Researchers explore new combination approach to treat high-risk soft-tissue sarcomas

Researchers create chimera virus that allows study of molecules to treat cancers

LSU Health New Orleans receives $10 million grant to support research on virus-induced cancers

Scientists develop new chimeric antibody to treat malignant cancers in dogs

Research identifies new gene fusions and mutations linked to GIST tumors

FDA approves fixed dose combination chemotherapy for subtypes of AML that have poor survival outcomes

Scientists propose therapeutic strategy to suppress formation of hereditary bony tumors

UCLA research in sarcoma provides much-needed roadmap for personalizing therapies

Existing drugs could help subgroup of patients with osteosarcoma, suggest scientists

Study finds steady decline in severe health problems for childhood cancer survivors

New targeted oral therapy results in durable responses across many kinds of cancer

Early study of experimental vaccine shows escalating immune response in patients with sarcoma

Rice University scientists develop and evaluate analogs of potent cancer fighters

Researchers identify DNA repair deficiency in many types of solid tumors

CNIO researchers optimize new system capable of generating cellular model of Ewing sarcoma

Use of videos can reduce need for anesthesia during radiotherapy for children with cancer

Study suggests how existing and emerging immunotherapy treatments could be successful for sarcomas

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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