Sarcoma News and Research

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Promising new treatment option for women with recurrent ovarian cancer

Combining the new drug trabectedin with pegylated liposomal doxorubicin provides clinical benefit to women with relapsed ovarian cancer, according to new results presented at the 33rd Congress of the European Society for Medical Oncology (ESMO) in Stockholm.

15 Sep 2008

Immunotherapy shows promise in high-risk pediatric sarcomas

Based on a pilot study in children with sarcoma, researchers at the National Institutes of Health (NIH) believe that immunotherapy could prove beneficial in treating high-risk forms of this cancer.

3 Aug 2008

Smoking among child cancer survivors highest in most at risk group

Childhood cancer survivors who are most at risk of developing a second cancer are more likely to smoke than other childhood cancer survivors - reveals a Cancer Research UK study published in the Journal of the National Cancer Institute.

3 Aug 2008

Oncolytics Biotech announces results for intravenous Reolysin in patients with sarcomas metastatic to the lung

Oncolytics Biotech Inc. has announced that interim results of a Phase II study of intravenous Reolysin in patients with sarcomas metastatic to the lung were presented yesterday at the American Society of Clinical Oncology (ASCO) annual meeting.

2 Jun 2008

Grassley inquiry into fast-tracking of Avastin drug applications could hurt cancer drug development, patients

Sen. Chuck Grassley's (R-Iowa) request that the Government Accountability Office investigate whether FDA acted appropriately in granting "accelerated approval" to a cancer drug "will have a catastrophic effect on America's ability to develop new drugs," Mark Thornton, a former medical officer in FDA's Office of Oncology Drug Products and president of the Sarcoma Foundation of America, writes in a Wall Street Journal opinion piece.

30 May 2008

Study finds increased risk of some cancers among HIV-positive people in U.S.

HIV-positive people in the U.S., many of whom are living longer because of antiretroviral drugs, are at an increased risk for certain types of cancers, according to a study published Tuesday in the Annals of Internal Medicine, Reuters reports.

22 May 2008

Washington Post examines lack of health care for undocumented immigrants in detention centers

The Washington Post as part of a four-day series, titled "Careless Detention," is examining how some immigrants to the U.S. do not receive needed health care while in immigration detention centers.

13 May 2008

microRNAs appear essential for retinal health

Retinas in newborn mice appear perfectly fine without any help from tiny bits of genetic material called microRNAs except for one thing - the retinas do not work.

7 May 2008

Most comprehensive kinome collection

Scientists from University of Helsinki, Institute of Molecular Medicine in Finland and OriGene Technologies joined effort in creating the most comprehensive kinome collection of nearly all predicted human protein kinases, including the functional kinases and their kinase-deficient counterparts. Equipped with this collection, the authors successfully identified novel kinase regulators in Hedgehog signaling pathway and in activation of Karposi's Sarcoma herpesvirus.

5 May 2008

Researchers report the cloning of a key group of human genes, the protein kinases

Although the human genome has been sequenced, research into mechanism of action of genes has been hampered by the fact that most human genes have not been isolated.

2 May 2008

New advance in use of oncolytic viruses as novel cancer treatments

Combining a herpes virus genetically altered to express a drug-enhancing enzyme with a chemotherapy drug effectively and safely reduced the size of highly malignant human sarcoma grafted into mice.

22 Apr 2008

Discovery of small molecule that disrupts Ewing's sarcoma oncogene

Researchers at Georgetown University Medical Center have found a small molecule they say can block the action of the oncogene that causes Ewing's sarcoma, a rare cancer found in children and young adults.

13 Apr 2008

Rreishi mushroom and green tea for cancer prevention

Both the reishi mushroom (Ganoderma lucidum; Lingzhi) and green tea have long held a place in traditional medicine in China and other Asian countries, for the general promotion of health and long life and for the treatment of specific diseases.

9 Apr 2008

Scans spot hidden tumors in Li-Fraumeni syndrome

Researchers at Dana-Farber Cancer Institute report that full-body PET/CT scanning detected unsuspected, treatable tumors in 3 of 15 patients with Li-Fraumeni syndrome (LFS), a rare genetic cancer syndrome for which no screening tests have been recommended.

19 Mar 2008

Study shows Parkinson's disease drug dopamine might work in cancer patients

A study published in the March 13 online issue of The Journal of Clinical Investigation shows that dopamine, a drug currently used to treat Parkinson's disease and other illnesses, also might work in cancer patients.

14 Mar 2008

Nanotechnology advances brain cancer detection and therapy

Brain cancer is one of the most aggressive and lethal of malignancies, made even more difficult to treat by the fact that most anticancer drugs have a hard time even getting to the tumors.

3 Mar 2008

Racial and ethnic differences among patients with extremity soft-tissue sarcomas

A new study reveals significant racial and ethnic differences in the treatment and survival of patients with soft-tissue sarcomas, a rare but dangerous cancer that begins in muscle, fat, blood vessels or other supporting tissue of the body.

23 Jan 2008

Previously unknown Merkel cell polyomavirus linked to deadly skin cancer

A new strategy to hunt for human viruses described in this week's issue of the journal Science by the husband-and-wife team who found the cause of Kaposi's sarcoma has revealed a previously unknown virus strongly associated with another rare but deadly skin cancer called Merkel cell carcinoma.

18 Jan 2008

Panzem (2-methoxyestradiol ) drug a possible candidate for breast cancer treatment

A Mayo Clinic study of a drug that has shown promise in treating sarcoma, lung and brain cancers, demonstrates that the drug may also be effective in treating breast cancer, in particular the spread of breast cancer.

2 Nov 2007

New theory of how viruses may contribute to cancer

A new study suggests that viruses may contribute to cancer by causing excessive death to normal cells while promoting the growth of surviving cells with cancerous traits.

24 Oct 2007