Schizophrenia

Schizophrenia is a chronic debilitating disorder which affects more than two million Americans, and millions more worldwide. While significant progress has been made in understanding the disease and developing treatments, there remains a significant unmet medical need. More than 50% of patients switch their medication in a given year due to either poor response or the experience of adverse events.

Schizophrenia

Schizophrenia is a chronic mental health disorder that causes people to think, feel and perceive the world differently from the general population.

Schizophrenia Diagnosis

Schizophrenia Causes

Schizophrenia Signs and Symptoms

Schizophrenia Neural Processes

Schizophrenia Mechanisms

Schizophrenia Screening, Prevention and Management

Schizophrenia Medication

Schizophrenia Interventions

Schizophrenia Prognosis

Latest Schizophrenia News and Research

Environmental stressors linked to fetal brain development challenges

Review article in the journal Antioxidants explores the impact of environmental factors on fetal and neonatal brain development, emphasizing the role of inflammation and oxidative stress from maternal stressors.

15 Apr 2024

Study finds dysfunction of key brain systems in people with psychosis

Inside the brains of people with psychosis, two key systems are malfunctioning: a "filter" that directs attention toward important external events and internal thoughts, and a "predictor" composed of pathways that anticipate rewards.

13 Apr 2024

Women predominantly treated for anxiety and depression at psychiatric outpatient clinics

More than 75% of the patients treated at the psychiatric outpatient clinic of Hospital de Base in São José do Rio Preto, São Paulo state (Brazil), are women with a mean age of 45 and suffering from sadness, anxiety and irritability, according to a study reported in the journal Frontiers in Psychiatry.

13 Apr 2024

Researchers identify the most harmful modifiable risk factors for dementia

Researchers from the Nuffield Department of Clinical Neurosciences at the University of Oxford have used data from UK Biobank participants to reveal that diabetes, traffic-related air pollution and alcohol intake are the most harmful out of 15 modifiable risk factors for dementia.

10 Apr 2024

Probiotics plus vitamin D supplements may improve cognitive function in individuals with schizophrenia

Previous studies have questioned whether gut microbe imbalances and vitamin D deficiency may be linked to schizophrenia.

10 Apr 2024

Researchers elucidate how gene mutation mechanism causes autism

Researchers show how mutations of gene transcription and chromatin regulation-related genes cause autism.

9 Apr 2024

Study shows association between childhood loneliness and first-episode psychosis

A new study suggests that children who felt lonely for more than 6 months before the age of 12 are more likely to experience an episode of psychosis than children who did not, with women more affected than men.

9 Apr 2024

Electroconvulsive Therapy found to be safe and effective treatment for some mental illnesses

Researchers have found that Electroconvulsive Therapy (ECT), where an electric current is passed through the brain, can reduce the severity of mental illnesses.

9 Apr 2024

Gut-friendly psychobiotics could brighten moods and fight depression

Review uncovers that psychobiotics may offer supportive treatment for depression by restoring gut microbiome balance and positively influencing the microbiome-gut-brain axis, which is crucial for mental health and well-being.

8 Apr 2024

Rise in severe psychiatric cases among children during the pandemic

A new study found that during the pandemic pediatric emergency departments (EDs) saw more children and adolescents who needed a psychiatric admission, as well as an increase in severe conditions, such as bipolar disorder, schizophrenia and substance use disorders.

2 Apr 2024

Ketogenic diet can be a powerful aid in treating mental illness

For people living with serious mental illness like schizophrenia or bipolar disorder, standard treatment with antipsychotic medications can be a double-edged sword.

1 Apr 2024

For-profit companies open psychiatric hospitals in areas clamoring for care

A for-profit company has proposed turning a boarded-up former nursing home here into a psychiatric hospital, joining a national trend toward having such hospitals owned by investors instead of by state governments or nonprofit health systems.

1 Apr 2024

Research offers first insights into the mechanism behind synaptic development

The first analysis of how synaptic proteins change during early development reveals differences between mice and marmosets but also what's different in individuals with autism spectrum disorders.

28 Mar 2024

Genetic and lifestyle factors linked to brain network aging, study reveals

Research highlights the impact of genetic and lifestyle factors on a brain network particularly sensitive to aging, schizophrenia, and Alzheimer's disease, using data from nearly 40,000 UK Biobank participants to investigate modifiable risk factors and genetic associations.

28 Mar 2024

Study reveals risk factors for faster aging in the brain

The researchers had previously identified a 'weak spot' in the brain, which is a specific network of higher-order regions that not only develop later during adolescence, but also show earlier degeneration in old age.

27 Mar 2024

Study identifies brain energy metabolism dysfunction in neuropsychiatric disorders

A global collaborative research group comprising 131 researchers from 105 laboratories across seven countries announces a groundbreaking research paper submitted to eLife.

26 Mar 2024

Understanding schizophrenia through genetics and neural pathways

Our understanding of schizophrenia has increased greatly in recent years, as studies of large groups of people have identified a multitude of genetic variants that increase a person's risk of the disease.

19 Mar 2024

Antipsychotic use during pregnancy not linked to childhood neurodevelopmental disorders or learning difficulties

The use of antipsychotics during pregnancy isn't linked to childhood neurodevelopmental disorders or learning difficulties, UNSW Sydney-led study shows – giving assurance to those concerned about continuing their medications during pregnancy.

18 Mar 2024

Non-invasive brain stimulation can change specific brain mechanism linked to human behavior

For the first time, researchers at the University of Minnesota Twin Cities showed that non-invasive brain stimulation can change a specific brain mechanism that is directly related to human behavior.

15 Mar 2024

The brain may use a single shared blueprint to guide early development, study suggests

In a new study published in Proceedings of the National Academy of Sciences (PNAS), researchers from the University of Minnesota Medical School investigated brain development to understand how different areas of the brain become specialized in handling information such as vision, sound, touch and planning.

11 Mar 2024