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People with very irregular sleep patterns may have higher dementia risk

People who have very irregular sleep patterns may have a higher risk of dementia than those who have more regular sleep patterns, according to new research published in the December 13, 2023, online issue of Neurology, the medical journal of the American Academy of Neurology.

13 Dec 2023

Idiopathic hypersomnia may not be as rare as previously thought

People who are very sleepy during the day, despite a good night's rest, may have a sleep disorder called idiopathic hypersomnia. New research has found this neurologic disorder may not be as rare as once thought.

13 Dec 2023

Novel molecular link between vitamin B12 and multiple sclerosis revealed in astrocytes

For decades, scientists have noted an intriguing similarity between a deficiency in vitamin B12 – an essential nutrient that supports healthy development and functioning of the central nervous system (CNS) – and multiple sclerosis (MS), a chronic disease in which the body's immune system attacks the CNS and which can produce neurodegeneration.

11 Dec 2023

Study provides a better understanding of how the brain responds to injuries

A new study published in Proceedings of the National Academy of Sciences Nexus provides a better understanding of how the brain responds to injuries.

11 Dec 2023

Scientists unveil 3D structure of key immune system component

An international team of researchers from LMU and the Helmholtz Centre for Infection Research has visualized the structure of the so-called ASC speck.

8 Dec 2023

Small molecule drug shows promise as potential new treatment for multiple sclerosis

CAMH-led pre-clinical studies using a small molecule drug have shown promise as a potential new treatment for multiple sclerosis (MS). The results have been published today in the journal Science Advances.

8 Dec 2023

Cryo-EM reveals TAF15 as potential treatment target for frontotemporal dementia

An international team of researchers including experts at the Indiana University School of Medicine has identified a protein found in the brains of people with frontotemporal dementia (FTD), discovering a new target for potential treatments for the disease.

7 Dec 2023

EU funds the international "BEHIND-MS" consortium to tackle multiple sclerosis

Multiple sclerosis (MS), an inflammatory disease of the central nervous system, affects more than 1 million people in Europe and an estimated 2.8 million worldwide.

7 Dec 2023

Scientists uncover key protein aggregation in frontotemporal dementia

Most neurodegenerative diseases, including dementias, involve proteins aggregating into filaments called amyloids.

6 Dec 2023

Military personnel repeatedly exposed to blasts show increased brain inflammation and structural changes

The brains of special warfare community personnel repeatedly exposed to blasts show increased inflammation and structural changes compared with a control group, potentially increasing the risk of long-term, brain-related disease, according to a new study.

6 Dec 2023

Depression, constipation, and UTIs may be early signs of multiple sclerosis

In some diseases, the underlying processes can start years before a diagnosis is made. A new study finds that people who later develop multiple sclerosis (MS) are more likely to have conditions like depression, constipation and urinary tract infections five years before their MS diagnosis than people who do not develop MS.

5 Dec 2023

Researchers evaluate possible mitochondrial factors in Alzheimer's pathogenesis

A group of authors critically evaluated and interpreted the evidence linking mitochondrial dysfunction and metabolic changes to the pathogenesis of Alzheimer's disease (AD).

5 Dec 2023

New insights into the interplay between prions and TDP-43 in neurodegenerative pathology

Neurodegenerative diseases are characterized by the deposition of clumped proteins in the brain and progressive neuronal cell death.

4 Dec 2023

New adaptive clinical trial aims to reverse neurological damage caused by progressive multiple sclerosis

The first-ever adaptive clinical trial for Australians living with MS will seek to reverse neurological damage caused by progressive multiple sclerosis.

4 Dec 2023

New insights on optimizing housing for individuals with spinal cord injury

Housing that fails to meet the needs of people with disabilities may have far-reaching consequences. Living situations that impede independence and community integration, for example, can adversely affect health and wellbeing over the long term.

1 Dec 2023

Study finds top three classes of medications more effective than ibuprofen for treating migraine attacks

For many people with migraine, it can be difficult to find a treatment that is effective and reliable, and information on how medications compare to one another is lacking.

29 Nov 2023

Abnormal myelin, not loss of myelin, may drive axon degeneration in myelin diseases

Myelin is an insulating sheath around axons - the processes connecting nerve cells - that is mostly composed of lipids and proteins.

28 Nov 2023

Researchers take step toward developing cell therapy treatment for MS

An international team has shown that the injection of a type of stem cell into the brains of patients living with progressive multiple sclerosis (MS) is safe, well tolerated and has a long-lasting effect that appears to protect the brain from further damage.

27 Nov 2023

Whole grain consumption associated with slower memory decline in Black people

Black people who eat more foods with whole grains, including some breads and cereals, quinoa, and popcorn, may have a slower rate of memory decline compared to Black people who eat fewer whole grain foods, according to a study published in the November 22, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.

22 Nov 2023

Sex-specific brain immunometabolism differences may underlie increased Alzheimer's risk in women

Cleveland Clinic researchers analyzed genes and brain tissue of patients with Alzheimer's and found that differences in brain immunometabolism – the interactions between the immune system and the ways cells create energy – may contribute to women's increased risk for the disease and its severity.

21 Nov 2023