Selective Serotonin Reuptake Inhibitor (SSRI) News and Research

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Selective Serotonin Reuptake Inhibitor (SSRI) is a type of drug that is used to treat depression. SSRIs slow the process by which serotonin (a substance that nerves use to send messages to one another) is reused by nerve cells that make it. This increases the amount of serotonin available for stimulating other nerves. Also called selective serotonin reuptake inhibitor.

SSRI antidepressants may be unsuitable for children

A UK study in this week's issue of THE LANCET suggests that reliance on published studies alone to guide the treatment of childhood depression could be inappropriate. A systematic review including published and unpublished data shows that only one drug, fluoxetine (Prozac), was not associated with negative outcomes for children with depression.

22 Apr 2004

Trials of antidepressants for children consistently exaggerated their benefits while playing down their possible harm

Antidepressants should not be used to treat children and teenagers, a controversial new Australian study has warned, saying clinical trials have exaggerated the benefits of the drugs and played down their side effects.

10 Apr 2004

Selective Serotonin Reuptake Inhibitor (SSRI) News and Research

Further Reading

SSRI antidepressants may be unsuitable for children

Trials of antidepressants for children consistently exaggerated their benefits while playing down their possible harm

Michael Stryker

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