Septic Shock News and Research

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AHSN already working to tackle sepsis across North East and North Cumbria

Doctors and nurses in the region have been working collaboratively for over a year to ensure the effective recognition and response to sepsis.

14 Jul 2016

iMDsoft launches new mobile e-obs solution for early detection of sepsis and AKI

iMDsoft announced that they will be featuring new and advanced tools for detecting patient deterioration at Patient Safety Congress in Manchester, 5 - 6 July 2016.

5 Jul 2016

Food components can have significant influence on immune system

An international team of researchers under the leadership of the LIMES Institute and the excellence cluster ImmunoSensation of the University of Bonn unraveled a new regulatory mechanism how food components and environmental factors influence the immune system.

18 May 2016

Researchers find evidence that protein involved in regulating inflammation has anti-septic effects

Sepsis represents a serious complication of infection and is one of the leading causes of death and critical illness worldwide due in part to the lack of effective therapies. A report in the American Journal of Pathology provides evidence from both mouse and human studies that SHARPIN, a protein involved in regulating inflammation, has anti-septic effects. These findings may spur development of novel sepsis treatments.

11 Apr 2016

Researchers disprove previously assumed behavior of macrophage immune cells

What happens when macrophage immune cells are activated in the course of an inflammation to combat pathogens such as bacteria or viruses? Researchers of the Luxembourg Centre for Systems Biomedicine of the University of Luxembourg pursued this very question. The researchers discovered that the immune cells behave differently from what was previously assumed. Their metabolism upholds the production of antimicrobial substances and fatty acids during activation. In this way, they deliver important resources for the immune responses they trigger.

21 Mar 2016

Gut microbial imbalance appears to be underlying cause of fatal intestinal illness in premature babies

An imbalance of certain gut microbes appears to be the underlying cause of a frequently fatal intestinal illness in premature babies, according to new research led by Washington University School of Medicine in St. Louis

9 Mar 2016

FDA clearance expands clinical claims of Thermo Scientific B•R•A•H•M•S PCT biomarker for sepsis risk assessment

Thermo Fisher Scientific Inc., the world leader in serving science, today announced it has received clearance from the U.S. Food and Drug Administration that expands the clinical claims of the Thermo Scientific B·R·A·H·M·S PCT biomarker assay for sepsis risk assessment.

From Thermo Fisher Scientific Inc. 2 Mar 2016

Protein p62 acts as molecular brake to keep inflammation in check, avoid collateral damage

Inflammation is a Catch-22: the body needs it to eliminate invasive organisms and foreign irritants, but excessive inflammation can harm healthy cells, contributing to aging and sometimes leading to organ failure and death. Researchers at University of California, San Diego School of Medicine have discovered that a protein known as p62 acts as a molecular brake to keep inflammation in check and avoid collateral damage.

26 Feb 2016

New definitions and clinical criteria for sepsis, septic shock

Clifford S. Deutschman, MS, MD, vice chair of research in the Department of Pediatrics at Cohen Children's Medical Center and an investigator at The Feinstein Institute for Medical Research , presented new definitions and clinical criteria for sepsis and septic shock at the Society of Critical Care Medicine's 45th Critical Care Congress in Orlando, FL.

24 Feb 2016

Bacteria lurking in dental water lines

Bacteria lurking in the water lines at the dentist's office are tougher than we thought, according to a new paper published in Water Research. The study reveals that the disinfectants recommended by companies that manufacture the water lines don't actually shift all the bacteria in the lines, which means they're never completely clean.

17 Feb 2016

Body can control pathogen-induced inflammatory response, find Georgia State researchers

The body can control inflammatory response triggered by invasions of microbial pathogens, such as bacteria and viruses, a discovery that could lead to the development of new therapeutic agents for uncontrolled inflammation, according to researchers at Georgia State University.

29 Dec 2015

Scientists reveal major players in severe muscle damage caused by sepsis

Scientists from the Institut Pasteur, Paris Descartes University, Sainte-Anne Hospital and the CNRS have recently published a paper in Nature Communications in which they reveal major players in the severe muscle damage caused by sepsis, or septicemia, which explains why many patients suffer debilitating muscle impairment long-term after recovery.

17 Dec 2015

Early promise for pulmonary artery denervation in PAH patients

Pulmonary artery denervation is feasible and may reduce pulmonary arterial pressure in patients with pulmonary arterial hypertension, phase II findings suggest.

11 Dec 2015

Promising new treatment for sepsis on the horizon

A promising new drug for sepsis is on the horizon thanks to new funding from the British Heart Foundation, which could help take the laboratory discovery into the clinic.

18 Nov 2015

Scientists identify gene that could lead to development of new treatments for sepsis

Scientists have identified a gene that could potentially open the door for the development of new treatments of the lethal disease sepsis.

22 Oct 2015

Wyss Institute scientists develop improved blood-cleansing therapeutic device to treat sepsis

Last year, a Wyss Institute team of scientists described the development of a new device to treat sepsis that works by mimicking our spleen. It cleanses pathogens and toxins from blood circulating through a dialysis-like circuit. Now, the Wyss Institute team has developed an improved device that synergizes with conventional antibiotic therapies and that has been streamlined to better position it for near-term translation to the clinic.

21 Aug 2015

Pitt unveils research-based guidance to improve compliance while treating sepsis

As hospitals nationwide brace for rigorous mandates for care of septic patients that will be adopted by the Centers for Medicare & Medicaid Services in October, a University of Pittsburgh School of Medicine review unveils research-based guidance to improve compliance when treating this common and deadly syndrome.

19 Aug 2015

McMaster University hematologist finds different limb loss syndromes

How people can develop limb gangrene and lose fingers and feet has baffled doctors for centuries. Now a McMaster University hematologist has identified different limb loss syndromes along with explanations for what is happening and what can be done about it.

13 Aug 2015

Johns Hopkins researchers report on more effective way to spot patients at risk of septic shock

For a patient with sepsis - which kills more Americans every year than AIDS and breast and prostate cancer combined - hours can make the difference between life and death.

6 Aug 2015

UAB research findings may lead to better treatment for women with HER2+ breast cancer

There are five subtypes of breast cancer, and they are distinct diseases with vastly different biologies that drastically alter their progression and responses to treatment. Understanding those differences is the starting point to a more effective, personalized treatment of breast cancer, which strikes more than 230,000 women in the U.S. each year.

16 Apr 2015