Serial Analysis of Gene Expression (SAGE) News and Research

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Study: Antidepressant drugs prove to be effective against SCLC patients

A bioinformatics approach to repurposing drugs resulted in identification of a class of antidepressants as a potential new treatment for small-cell lung cancer (SCLC), according to a study published in Cancer Discovery, a journal of the American Association for Cancer Research.

27 Sep 2013

Wiley to grant access to research via patientACCESS

John Wiley & Sons, Inc., has announced it will join patientACCESS, a new program which offers low-cost access to medical and scientific research articles to patients and caregivers.

12 Sep 2013

Race and ethnicity, education and economics are linked to how well American families fare

After a period of relative calm during the 1990s, rapid changes in American families began anew during the 2000s, a new analysis suggests.

11 Sep 2013

New study explores pathways that lead to jail time for women

How do pathways to jail vary for females who are victims of specific types of trauma? New research published in Psychology of Women Quarterly, a SAGE journal, pinpoints the types of trauma such as caregiver violence, witnessing violence, and intimate partner violence, that lead to specific types of offending later in life and offers explanations based on real experiences.

3 Aug 2013

New study assesses impact of junior doctor changeover in quality and safety of patient care

New research suggests that failure by junior doctors in their annual changeover period to identify deteriorating patients and poor prioritisation skills are likely to drive a reduction in the quality and safety of patient care. Next Wednesday 7 August thousands of newly qualified doctors will take up their first hospital jobs and junior doctors will become a grade more senior. This period is associated with worse clinical outcomes than the rest of the year.

3 Aug 2013

ICSD, SAGE launch journal that provides information on drugs to public and professionals

SAGE and the Independent Scientific Committee on Drugs (ICSD) today announced the launch of Drug Science, Policy and Law, an online journal supporting the ICSD's goals of providing accessible information on drugs to the public and professionals.

2 Aug 2013

New NIH projects to target Fragile X syndrome, nicotine addiction and AMD

The National Institutes of Health has launched three innovative projects that will focus on development of therapeutics for Fragile X syndrome, nicotine addiction, and age-related macular degeneration. These projects are funded through the NIH Blueprint Neurotherapeutics Network which provides access to a variety of drug development resources.

1 Aug 2013

Research team receives NCI grant to develop precision therapies that kill cancer cells

A research team headed by Fred Hutchinson Cancer Research Center scientists Christopher Kemp, Ph.D., and Carla Grandori, M.D., Ph.D., has received a $4 million grant from the National Cancer Institute to develop precision therapies that selectively kill cancer cells while sparing normal, healthy tissue.

24 Jul 2013

Overall risk of injury death is lower in urban areas compared to outside of cities

Overturning a commonly-held belief that cities are inherently more dangerous than suburban and rural communities, researchers from the Perelman School of Medicine at the University of Pennsylvania and the Children's Hospital of Philadelphia (CHOP) have found that risk of death from injuries is lowest on average in urban counties compared to suburban and rural counties across the U.S.

24 Jul 2013

Study upends common perception that urban areas are more dangerous than small towns

Large cities in the U.S. are significantly safer than their rural counterparts, with the risk of injury death more than 20 percent higher in the country. A study to be published online tomorrow in Annals of Emergency Medicine upends a common perception that urban areas are more dangerous than small towns ("Safety in Numbers: Are Major Cities the Safest Places in the U.S.?").

23 Jul 2013

The number and severity of lower limb amputations have decreased in US

There have been dramatic decreases in the number and severity of lower limb amputations over the past decade, according to a new study published in the July 2013 issue of Foot & Ankle International.

12 Jul 2013

UBC researchers develop vaccine to halt spread of West Nile Virus in birds

University of British Columbia researchers have developed a vaccine that may halt the spread of West Nile Virus among common and endangered bird species.

10 Jul 2013

UA research shows emotional cooperation in men and women may be quite different

Cooperation is essential in any successful romantic relationship, but how men and women experience cooperation emotionally may be quite different, according to new research conducted at the University of Arizona.

27 Jun 2013

British post-menopausal women less likely to access appropriate treatment for vaginal atrophy

New data, published today in Menopause International, suggests that post-menopausal women in Britain are experiencing less sex, and less satisfying sex compared to their European and North American counterparts1, because they are considerably less likely to access appropriate treatment for a common, taboo condition called vaginal atrophy1.

20 Jun 2013

UCSC experts awarded $3.5M NIH grant to develop cancer genomics tools

Despite some successes, predicting cancer outcomes based on the molecular signatures in cancer cells remains a major challenge. A new effort, funded by the National Cancer Institute and led by researchers at the University of California, Santa Cruz, aims to clear several key roadblocks that have stymied progress in this field.

18 Jun 2013

Research: Breast cancer screening does not show effect on mortality statistics

New research analysing breast cancer mortality data spanning almost 40 years concludes that breast cancer screening does not yet show an effect on mortality statistics.

12 Jun 2013

Second-annual SINAInnovations conference to highlight power of Team Science

Leaders in health care, technology, design, the military and the arts will gather at The Mount Sinai Medical Center for the second-annual SINAInnovations conference on November 18 and 19, 2013.

10 Jun 2013

Elective hernia surgery offers value-for-money, improves quality of life for patients

New research suggesting that elective hernia surgery offers value-for-money and improved quality of life for patients has been published by the Journal of the Royal Society of Medicine.

30 May 2013

WHO: Single dose of vaccination sufficient to confer life-long immunity against yellow fever disease

The yellow fever 'booster' vaccination given ten years after the initial vaccination is not necessary, according to WHO.

17 May 2013

SAGE announces launch of new international open access journal of sports medicine

SAGE today announces the launch of a new international open access journal, the Orthopaedic Journal of Sports Medicine. This journal was developed by the American Orthopaedic Society for Sports Medicine in collaboration with professional sports medicine organizations from around the world as a global, peer-reviewed open access journal that will publish content for both researchers and practitioners studying orthopeadic sports medicine, arthroscopy, and knee arthroplasty.

5 May 2013