Single Nucleotide Polymorphisms News and Research

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Gout unveiled as surprising culprit in neurodegenerative diseases

Research highlights the association between gout and neurodegenerative diseases, revealing that gout patients exhibit smaller brain volumes, increased brain iron markers, and a higher incidence of conditions such as dementia, Parkinson's disease, and essential tremor, particularly within the first three years after diagnosis.

22 May 2023

Is there an association between long-term plasma caffeine intake and adiposity, type 2 diabetes, and cardiovascular diseases?

Investigate the effects of long-term exposure to higher plasma caffeine concentrations on T2D, adiposity, and cardiovascular diseases.

18 May 2023

Study extends understanding of m6A modification as biological pathway underlying atrial fibrillation

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Numerous single nucleotide polymorphisms (SNPs) have been identified as genetic contributors to atrial fibrillation (AF).

11 May 2023

Neanderthal genes shape human noses

Research reports a study on the genetics of facial features in Latin Americans using automatic landmarking of 2D portraits and genome-wide association analysis. The study identified novel regions associated with facial features, including a region in 1q32.3 that shows introgression from Neanderthals and influences nasal height.

10 May 2023

UC research examines link between genetics and the presence of opioid use disorder

New research out of the University of Cincinnati examines the association between genetics and the presence of opioid use disorder.

27 Apr 2023

Study identifies an unknown SARS-CoV-2 lineage on three mink farms in Poland

Researchers detected a cryptic severe acute respiratory syndrome coronavirus 2 lineage on mink farms in Poland.

24 Apr 2023

Early life adversity linked to accelerated neurobiological aging, raising vulnerability to depression and Alzheimer's

scientists investigate the neurocognitive correlates of genetic vulnerability to major depressive disorder and Alzheimer's disease.

30 Mar 2023

Study finds minimal impact of SARS-CoV-2 genome variability on current diagnostic molecular systems

The authors of a new study under review at the journal Scientific Reports and currently posted to the Research Square preprint* server proposed a novel analysis pipeline to help identify mutations in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reverse transcription-polymerase chain reaction (RT-PCR) primer regions.

29 Mar 2023

Possible pathways of C. auris emergence and the hypothetical role of interspecies transmission

Researchers summarized the current understanding of the emergence and ecologic niches of Candida auris.

27 Mar 2023

Higher plasma caffeine concentrations might reduce body fat and type 2 diabetes risk

In a recent study published in the journal BMJ Medicine, researchers in the United Kingdom and Sweden investigated the probable causality of long-term serum caffeine concentrations on type 2 diabetes (T2D), adiposity, and major cardiovascular diseases (CVDs).

22 Mar 2023

Childhood and adolescent obesity: time to act

In a recent review published in the journal Frontiers in Pediatrics, researchers at the Medical College of Wisconsin presented an overview of the pathophysiological mechanisms, health implications, and management options for obesity among children and adults.

21 Mar 2023

Study summarizes two cases of Cronobacter illness in infants linked to powdered infant formula and breast pump equipment

The findings indicate that C. sakazakii bacteria are common in the environment, and protocols for safe and hygienic food preparation for infants are essential.

6 Mar 2023

What is the effect of maternal circulating amino acids on offspring birthweight?

Researchers examined the effect of serum levels of 20 amino acids in a mother during pregnancy on offspring birthweight in a two-sample summary data Mendelian randomization framework.

27 Feb 2023

MicroRNAs associated with diabetes in human pancreatic islets

In a recent study published in the Proceedings of the National Academy of Sciences, researchers explored micro-ribonucleic acids (RNAs) associated with diabetes and related characteristics in human pancreatic islets.

13 Feb 2023

Increase in resistant Shigella infections among men who have sex with men

Researchers report a rise in Shigella flexneri type 2a infections in men who have sexual intercourse with men in England from September 2021 onward.

7 Feb 2023

Detecting novel SARS-CoV-2 variants via rapid RT-PCR assays

A new study on the medRxiv* preprint server assessed whether a novel assay could detect VOCs without substantial reductions in sensitivity.

6 Feb 2023

Using genetic risk scores for predicting venous thromboembolism

Researchers assess the predictability of venous thromboembolism among adults using genetic risk scores.

5 Feb 2023

SARS-CoV-2 infections on French mink farms after one year of COVID-19

A new paper, which appears on the bioRxiv* preprint server, describes the investigation of all French mink farms towards the end of 2020. This was to maximize the chances of identifying SARS-CoV-2 infection in these animals at any time over the past year.

3 Feb 2023

Impaired glucose tolerance and cardiovascular risk factors associated with fertility problems

The present study provided strong evidence that supported the hypothesis that hyperinsulinemia and glucose intolerance cause infertility in women.

31 Jan 2023

Combination of multiple maps uncovers new genetic risk factor for AMD

Combining a map of gene regulatory sites with disease-associated loci has uncovered a new genetic risk factor of adult-onset macular degeneration (AMD), according to a new study publishing January 17th in the open access journal PLOS Biology by Ran Elkon and Ruth Ashery-Padan of Tel Aviv University, Israel, and colleagues.

18 Jan 2023