Single Nucleotide Polymorphisms News and Research

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SARS-CoV-2 variant identification by RT-qPCR assays targeting mutations

In a recent study posted to the medRxiv* preprint server, researchers investigated the efficacy of diagnostic tests for identifying severe acute respiratory syndrome coronavirus (SARS-CoV-2) variants of concern (VOCs).

8 Mar 2022

Delta and Omicron coinfections identified in France

A new study shows both the Omicron and Delta variants were able to infect patients with healthy immune function.

7 Mar 2022

Similarities between SARS-CoV-2 and human retroelements explored

A new study investigated the similarities between SARS-CoV-2 and human retroelements.

2 Mar 2022

A study on the evolution of avian coronavirus escape mutants in vitro

A recent study included an in vitro assessment of the effect of antibody titers and vaccine combinations on the emergence of escape mutants of AvCoV.

28 Feb 2022

First reported case of a cat infected with SARS-CoV-2 Delta AY.3 variant

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is hurting our loved ones — even those that walk on four legs. Researchers from the University of Pennsylvania documented the recovery of an 11-year old indoor housecat living in Delaware who first presented to the veterinary hospital after experiencing distressing gastrointestinal symptoms.

23 Feb 2022

Monitoring rise of SARS-CoV-2 variants in wastewater using genome sequencing

Researchers conduct genomic wastewater surveillance of SARS-CoV-2 following the emergence of the Alpha and Delta variants in the United Kingdom.

21 Feb 2022

ChAdOx1 vaccine found to protect Syrian hamsters against SARS-CoV-2 variants

Researchers recently evaluated the efficacy of the Oxford ChAdOx1 (AZD 1222/ AZD2816) vaccine against the Omicron, Delta, and Beta variants of SARS-CoV-2 in Syrian hamsters.

17 Feb 2022

Spillover of SARS-CoV-2 Omicron variant infection in white-tailed deer in New York

Researchers detected evidence for SARS-CoV-2 Omicron variant exposure in the white-tailed deer population inhabiting Staten Island in New York.

10 Feb 2022

Causality of associations between maternal BMI and child adiposity

Researchers modified the MR study methodologies to ensure a bias-proof evaluation of the causal effect of maternal BMI on offspring adiposity.

9 Feb 2022

Detection of SARS-CoV-2 Delta variant infection in a domestic cat

The first published case describing the Delta variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a domestic cat in the United States highlights the realistic scenario of spillover infections with emerging viral variants that threaten human and animal health.

6 Feb 2022

Oligodendrocytes may have a different role in the development of multiple sclerosis, study finds

An international team of researchers led by Karolinska Institutet in Sweden have discovered that a cell type in the central nervous system known as oligodendrocytes might have a different role in the development of multiple sclerosis (MS) than previously thought.

28 Jan 2022

Genetic marker linked to higher risk of death in COVID-19 patients

A new study discusses the importance of single nucleotide polymorphisms in the Rab46 gene as a marker of adverse outcomes in high-risk COVID-19 patients.

23 Jan 2022

Recombinant bat coronavirus reported in wide-ranging Cambodian bat

A new study reports on the detection of recombinant coronaviruses in several bat species in Cambodia and of a related species in China.

20 Jan 2022

Newly developed risk scores can help identify childhood obesity risk

Newly developed risk scores synthesize genetic information into an easy-to-interpret metric that could help clinicians identify young children most at risk of developing obesity.

10 Jan 2022

Researchers outline characteristics of Omicron variant immune escape and viral entry into host cells

A new study found that the Omicron variant contains a number of mutations that decrease neutralizing antibody activity and immune escape.

6 Jan 2022

Are our bowel habits written in our DNA?

In this interview, News-Medical talks to Dr. Mauro D’Amato about how there could be clues about the regularity of bowel movements within our genes.

24 Dec 2021

SARS-CoV-2 infection leads to distinct changes in proteomic and peptidomic profiles and posttranslational modifications

A new study indicates that as a result of SARS-CoV-2 infection comprehensive changes in protein processing and regulation occur.

20 Dec 2021

Investigating SARS-CoV-2 genomics-informed outbreaks using new bioinformatics tools

Researchers have created a tool designed to make as much use of the overwhelming amount of SARS-CoV-2 data as possible.

17 Dec 2021

Phenome study reveals alternate associations with SARS-CoV-2 risk loci

Researchers from the Duke Molecular Physiology Institute have been investigating genetic associations with more severe disease and examining the associations that certain genetic features have with other diseases.

13 Dec 2021