Small Intestine News and Research

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Gut hormone receptor polyagonists show promise for obesity and diabetes

A new paper in the Journal of Clinical Investigation describes drugs that could help lose weight and manage type 2 diabetes mellitus (T2DM).

6 Feb 2023

New insights on bile duct and gallbladder cancers

Bile duct and gallbladder cancers are uncommon, with an estimated 12,130 new cases diagnosed this year according to the American Cancer Society.

30 Jan 2023

Microbial polyphenols in Mediterranean diet improve cardiovascular health

Researchers observe a robust association between urinary phenolic metabolites, Mediterranean diet adherence, and a healthier cardiovascular status.

29 Jan 2023

Novel method makes genetic analyses possible for all regions of the intestine

With its length and multitude of folds and protrusions, the intestine represents the largest contact surface between our body and the food taken up from the outside.

23 Jan 2023

Study directly links gut leakage with retinopathy severity in people with Type 1 diabetes

The leading cause of blindness in American adults is diabetic retinopathy, progressive damage to blood vessels in the light-sensitive tissue at the back of the eye.

14 Jan 2023

Valuable tool reveals the connections between gut microbes and the brain

In the past decade, researchers have begun to appreciate the importance of a two-way communication that occurs between microbes in the gastrointestinal tract and the brain, known as the gut–brain axis.

13 Jan 2023

Orally administered insulin tablet powered by chemical micromotors

For the millions of people living with diabetes, insulin is a life-saving drug. Unlike many other medicines, though, insulin cannot be easily delivered by swallowing a pill -; it needs to be injected under the skin with a syringe or pump.

9 Jan 2023

The metabolic links between diet-induced changes in the gut and NASH

Scientists reviewed the metabolic association between diet-induced alterations in the gut and NASH

4 Jan 2023

Salk scientists find a system-wide, molecular impact of time-restricted eating in mice

Numerous studies have shown health benefits of time-restricted eating including increase in life span in laboratory studies, making practices like intermittent fasting a hot topic in the wellness industry.

3 Jan 2023

Study reveals a previously unappreciated complexity of TRM cell biology in the gut

Recent pressure to maximize vaccine efficacy has stirred up many new discoveries within immunology, revealing numerous paradigms with untapped therapeutic potential.

28 Dec 2022

When it comes to harvesting energy, some guts do it better than others

New research from the University of Copenhagen suggests that a portion of the Danish population has a composition of gut microbes that, on average, extracts more energy from food than the microbes in their fellow Danes' guts.

25 Dec 2022

The implications of pulmonary tissue-resident memory T lymphocytes in COVID-19 and other respiratory diseases

Researchers elucidated the mechanisms of long-term T lymphocyte lodgement in tissues other than lymphoid tissues and the reasons for the transient residency of specific subsets of tissue-resident memory T (TRM) lymphocytes.

14 Dec 2022

Biobattery researchers have a solution for the hard-to-reach small intestine

Tech companies have developed many devices that work outside the body, such as cell phones, smart watches, tablets and hundreds of others. Inside the body, though? That's obviously trickier for several reasons, but power for a device is a big one.

12 Dec 2022

Researchers develop a self-powered ingestible sensor system to monitor intestinal metabolites

Engineering researchers have developed a battery-free, pill-shaped ingestible biosensing system designed to provide continuous monitoring in the intestinal environment.

1 Dec 2022

SARS-CoV-2 can cause hyperglycemia in cats

In a recent study published in The Journal of Infectious Diseases, researchers explored the association between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and hyperglycemia in cats.

30 Nov 2022

Gut microbial flavonoid catabolite reverses fatty liver disease in mice

Researchers report that a gut microbial catabolite could reduce the cardiometabolic disease burden in mice.

29 Nov 2022

Fermented dairy products can improve gut mucosal immunity

In a recent study published in the journal Immunology Letters, researchers assessed the role of fermented dairy products and dairy starters in modulating gut mucosal immunity.

3 Nov 2022

Researchers study the unique adaptability of small intestinal bacteria for the first time

Bacteria in the small intestine adapt dynamically to our nutritional state, with individual species disappearing and reappearing.

1 Nov 2022

Did COVID-19 mitigation measures in the United Kingdom impact the transmission of other infectious diseases?

Researchers explored the impact of the coronavirus disease 2019 (COVID-19) pandemic-associated non-pharmaceutical prevention measures on the transmission of 22 infectious diseases in England.

25 Oct 2022

Increased TMPRSS2 expression in tongue tissue of females and alcohol drinkers identified as a potential risk factor for SARS-CoV-2 infection

Researchers explored the association between the expressions of the ACE-2 receptor and TMPRSS2 in the tongue tissue and dysgeusia during SARS-CoV-2 infections.

17 Oct 2022