Smallpox News and Research

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Smallpox is a highly contagious disease caused by the variola virus, a member of the Orthopox virus family. It is one of the most devastating diseases known to humanity, with a mortality rate as high as 30%. In 1967, the World Health Organization embarked upon an intensified vaccination campaign to eliminate smallpox, which culminated in the successful eradication of the disease globally by 1980.

By the mid-1980s, there were only two known repositories of variola virus: the Institute of Virus Preparations in Russia, and the US CDC. The events in the US in September and October 2001 highlighted the risk that the variola virus might be used as an agent of bioterrorism. Governments around the world are taking precautionary measures to be ready to deal with a potential smallpox outbreak.

Decision to destroy remaining stocks of the smallpox virus has again been postponed

The World Health Organization (WHO), meeting in Geneva have now decided that more research needs to be carried out on Smallpox.

22 May 2005

UN wants ban on creation of smallpox virus in labs

Health officials around the world are being urged by United Nations experts to ban scientists from making the deadly smallpox virus in laboratories for fear it could fall into terrorist hands.

18 May 2005

The Gates Foundation approach to the world's health problems has its critics

A recent article in The Lancet criticized the premise that a Grand Challenge to scientific and technological know-how is the best route to combating malaria, HIV/AIDS, tuberculosis and other diseases that kills millions of people each year.

16 May 2005

NIAID has awarded 10 grants and 2 contracts totaling approximately $27 million to fund development of new therapeutics and vaccines against bioterrorism

The National Institute of Allergy and Infectious Diseases (NIAID) has awarded 10 grants and 2 contracts totaling approximately $27 million to fund development of new therapeutics and vaccines against some of the most deadly agents of bioterrorism including anthrax, botulinum toxin, Ebola virus, pneumonic plague, smallpox and tularemia.

11 May 2005

Fragile US vaccine system needs improvement

A comprehensive system of vaccine development in the U.S. resulted in a reduction of 87 to more than 99 percent in illness from ten vaccine-preventable diseases during the twentieth century. These dramatic successes should not be taken for granted, however, as the vaccine system now faces numerous challenges in manufacturing and development, according to a review article in the May/June issue of Health Affairs.

10 May 2005

Smallpox-free for 25 years

It was in May 1980 that the World Health Assembly certified the world free of naturally occurring smallpox and the war against smallpox was won. Eradication was achieved through international vaccination programmes, global disease surveillance and public health logistics systems.

8 May 2005

No serious adverse events found with next-generation smallpox vaccine

Interim data from a phase I/II clinical trial of a next-generation vaccine for smallpox suggest that the vaccine may provide immunity and thus far the trial has been without any serious adverse events.

22 Mar 2005

Biologists discover why 10% of Europeans are safe from HIV infection

Scientists have known for some time that these individuals carry a genetic mutation (known as CCR5-Ä32) that prevents the virus from entering the cells of the immune system but have been unable to account for the high levels of the gene in Scandinavia and relatively low levels in areas bordering the Mediterranean.

9 Mar 2005

FDA approval of Vaccinia Immune Globulin to treat adverse reactions to smallpox vaccination

Computer Sciences Corporation today announced that the U.S. Food and Drug Administration (FDA) has approved its Vaccinia Immune Globulin (VIGIV), an intravenous immune globulin, to treat rare adverse reactions to smallpox vaccination.

22 Feb 2005

FDA approves new smallpox vaccination

The U.S. Food and Drug Administration (FDA) has approved Vaccinia Immune Globulin Intravenous (VIGIV) - the first intravenous human plasma-derived product available to treat certain rare complications of smallpox vaccination.

20 Feb 2005

Vaccination Week, largest immunization drive in the Americas

Health workers in every country in the Western Hemisphere are preparing strategies, purchasing vaccines, and coordinating logistics for the largest immunization drive in the Americas, targeting millions of children for Vaccination Week in the Americas, starting April 23.

13 Feb 2005

PAHO vaccines books wins major award

The Pan American Health Organization’s publication, Vaccines: Preventing Disease and Protecting Health, has won an award from the Association of American Publishers in the medical science category.

9 Feb 2005

New technique can greatly facilitate the development of vaccines against infectious diseases such as smallpox, malaria and tuberculosis

Because the new technique can synthesize a large number of proteins very quickly, it has potential to accelerate vaccine development, particularly crucial in the fight against bioterrorism.

25 Jan 2005

Vaccine Treatment and Evaluation Units (VTEUs) supply the nurse power necessary to beat back or altogether prevent infectious disease

Flu. Smallpox. Anthrax. Whooping cough. The words represent a veritable murderers' row of infectious agents whose death toll runs in the millions.

23 Dec 2004

Britain pledges four million doses of smallpox vaccine to a new global stockpile

Britain's Health Secretary John Reid today pledged to contribute four million doses of smallpox vaccine to a new global stockpile being assembled by the World Health Organisation.

13 Dec 2004

Oral administration of saline spray may stop spread of influenza, tuberculosis, and SARS

Some individuals exhale many more pathogen-laden droplets than others in the course of ordinary breathing, scientists have found, but oral administration of a safe saline spray every six hours might slash exhalation of germs in this group by an average 72 percent.

29 Nov 2004

Animal research and its benefits to both humans and animals

From preventing polio to finding cures for cancer patients, animal research has saved countless lives.

18 Nov 2004

Vaccine contributions to health highlighted at PAHO meeting

Vaccine programs in the Americas have made major contributions to improving health in the Americas and new vaccines could go even further, said Dr. D.A. Henderson, a global expert who chairs a Pan American Health Organization (PAHO) technical group here today.

4 Nov 2004

$73 million to tackle infectious diseases such as West Nile virus and influenza

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), has awarded 14 contracts totaling more than $73 million to fund the Large-Scale Antibody and T Cell Epitope Discovery Program, an initiative aimed at quickly identifying the regions of selected infectious agents that elicit immune reactions.

1 Nov 2004

BMA report hopes to raise awareness about the threat of biological weapons

A new report released today (25 October 2004) by the BMA paints a bleak picture of the global community's ability to cope with advances in biological and genetic weapons technology.

25 Oct 2004