Spectrometry News and Research

RSS

New study examines factors that may lead to end stage renal disease

About 33 percent of people with type 2 diabetes suffer kidney damage that progresses to end stage renal disease, at which point they require either dialysis or kidney transplantation. Scientists have thought that this kidney disease is driven by damage to the glomeruli, blood vessels in the kidney, which spill the protein albumin into the urine. Current treatments targeting the resulting "albuminuria" do not prevent kidney failure.

15 Jan 2014

Monitoring air pollution now possible with technological advances in air quality measurement methods

Launching a natural research experiment in Kathmandu, Nepal, this month using advanced monitoring methods to assess health risk from air pollution, environmental health scientist Rick Peltier at the University of Massachusetts Amherst hopes to demonstrate for the first time in a real-world setting that air pollution can and should be regulated based on toxicology variables rather than simply on the volume of particles in the air.

9 Jan 2014

Plasma thermogram can serve as an indicator of cervical cancer

Researchers at the University of Louisville have confirmed that using the heat profile from a person's blood, called a plasma thermogram, can serve as an indicator for the presence or absence of cervical cancer, including the stage of cancer.

8 Jan 2014

Researchers explore treatment targets for hypobaric hypoxia brain injury

Hypobaric hypoxia can cause severe brain damage and mitochondrial dysfunction, and is involved in hypoxic brain injury. Dr. Jianyu Li and colleagues from Logistics College of Chinese People's Armed Police Forces evaluated the degree of brain damage with different exposure times to hypoxia and further investigate the differential expression of cerebral mitochondrial proteins by comparative proteomic analysis, in a broader attempt to search for treatment targets of hypobaric hypoxia brain injury.

6 Jan 2014

Scientists obtain detailed molecular structure of member of Tet family of enzymes

Scientists have obtained the first detailed molecular structure of a member of the Tet family of enzymes.

28 Dec 2013

International researchers study glycans that could help clinicians diagnose gastric cancer early

Gastric cancer kills more than 700,000 people each year, mostly in Latin America, Asia and Eastern Europe. Though the disease is quite treatable when caught early, symptoms are indistinct and late detection leads to high mortality. The five-year survival rate in the United States is 26.9 percent.

22 Dec 2013

Two GW professors named 2013 Fellows of the National Academy of Inventors

Ferid Murad and Akos Vertes-two of George Washington University's scientific pioneers-are among the 143 innovators who have been named 2013 Fellows of the National Academy of Inventors.

19 Dec 2013

Mitochondrial enzyme SIRT5 regulates proteins involved in metabolism

The Sirtuin family of protein deacylases has received considerable attention in recent years due to its links to longevity, diabetes, cancer, and metabolic regulation.

12 Dec 2013

Scientists target protein-detection approach to systematically measure human repertoire of proteins

An international team of scientists led by Fred Hutchinson Cancer Research Center cancer proteomics expert Amanda Paulovich, M.D., has demonstrated the feasibility of large-scale, standardized protein measurements, which are necessary for validation of disease biomarkers and drug targets.

9 Dec 2013

AB SCIEX launches IVD-MS Analyzer CE marked for general in vitro diagnostic use in Europe

Continuing to rapidly expand its presence in the clinical diagnostics field, AB SCIEX, a global leader in analytical technologies, today announced the launch of its AB SCIEX IVD-MS™ Analyzer CE marked for general in vitro diagnostic use in Europe.*

27 Nov 2013

Bruker receives FDA clearance to market MALDI Biotyper CA System in the U.S.

Bruker Corporation today announced that it has been granted U.S. FDA clearance under Section 510(k) to market its MALDI Biotyper CA System in the United States for the identification of Gram negative bacterial colonies cultured from human specimens.

26 Nov 2013

Natural compound coumarins exhibit anti-inflammatory as well as anticoagulant activities

New methods for the laboratory-scale synthesis of coumarin-based drugs were developed in a recent study completed at the University of Eastern Finland. In his doctoral thesis, Lic. Phil. Juri Timonen also developed new analytical methods for the fast identification of natural and non-natural coumarins.

26 Nov 2013

Researchers discover how type 2 diabetes drug metformin actually works

Researchers from St. Vincent's Institute of Medical Research in Melbourne, Australia, in collaboration with researchers at McMaster University in Canada, are reportedly the first to discover how the type 2 diabetes drug metformin actually works, providing a molecular understanding that could lead to the development of more effective therapies. Mass spectrometry technologies from AB SCIEX, a global leader in analytical technologies, played a critical role in the analysis that led to this breakthrough finding.

25 Nov 2013

Biochemical signal in blood is associated with faster-progressing form of Parkinson's

The physical decline experienced by Parkinson's disease patients eventually leads to disability and a lower quality of life. Depending on the individual, the disorder can progress rapidly or slowly.

25 Nov 2013

Staphylococcus Aureus Bacteria anticipates and turns immune defenses against the host

Around 20 percent of all humans are persistently colonized with Staphylococcus aureus bacteria, a leading cause of skin infections and one of the major sources of hospital-acquired infections, including the antibiotic-resistant strain MRSA.

20 Nov 2013

Mount Sinai biologist wins NIH Director's New Innovator Awards for High-Risk, High Reward Research

Arvin Dar, PhD, structural and chemical biologist in oncological sciences at the Icahn School of Medicine at Mount Sinai, is one of 41 national recipients of the prestigious National Institutes of Health (NIH) Director's New Innovator Awards for High-Risk, High Reward Research. The award will support Dar's research into Ras-dependent cancers, specifically investigating how to combat mutations in Ras, a protein implicated in at least one of every five cancers.

16 Nov 2013

Mediterranean sofrito linked with low incidence of cardiovascular effects

The Mediterranean sofrito, the typical tomato-based sauce that seasons many dishes, has a high concentration of polyphenols which are associated with a low incidence of cardiovascular effects.

16 Nov 2013

Study: Sofrito helps to prevent cardiovascular diseases and cancer

The combination of tomato, olive oil, garlic and onion in a sofrito increases the amount of polyphenols and carotenoids. These bioactive compounds respectively help to prevent cardiovascular diseases and cancer.

15 Nov 2013

Early detection of breast cancer could soon be possible with blood test

What could someday be the first blood test for the early detection of breast cancer was shown in preliminary studies to successfully identify the presence of breast cancer cells from serum biomarkers, say the Houston Methodist Research Institute scientists who are developing the technology.