Spinal Cord Injury News and Research

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A spinal cord injury usually begins with a sudden, traumatic blow to the spine that fractures or dislocates vertebrae. The damage begins at the moment of injury when displaced bone fragments, disc material, or ligaments bruise or tear into spinal cord tissue. Most injuries to the spinal cord don't completely sever it. Instead, an injury is more likely to cause fractures and compression of the vertebrae, which then crush and destroy the axons, extensions of nerve cells that carry signals up and down the spinal cord between the brain and the rest of the body. An injury to the spinal cord can damage a few, many, or almost all of these axons. Some injuries will allow almost complete recovery. Others will result in complete paralysis.

Drugs that block mineralocorticoid receptor may help protect bone cells during aging

Drugs we take like prednisone can weaken our bones and so can aging, and scientists working to prevent both have some of the first evidence that the best target may not be the logical one.

5 Jan 2022

‘Moving molecule’ therapy for severe spinal cord injury

In this interview, News-Medical speaks to Dr. Stupp about his recent research into a therapy involving dancing molecules for the treatment of severe spinal cord injury.

7 Dec 2021

Tighter blood pressure management may lead to better spinal cord injury recovery

Patients with new spinal cord injuries whose blood pressure is maintained within a newly defined range during surgery may stand a better chance of regaining some mobility and functionality – even in patients with the most devastating injuries – according to a new study by researchers at UC San Francisco.

16 Nov 2021

Special bioactive scaffolds lead to greater functional recovery from spinal cord injury in mice

In mice with a spinal cord injury, mixing materials including bioactive sequences formed a polymer meshwork that improved axon regrowth, angiogenesis, and neuronal cell survival.

11 Nov 2021

New therapy harnesses "dancing molecules" to reverse paralysis, repair tissue after spinal cord injuries

Northwestern University investigators have developed a new injectable therapy that harnesses "dancing molecules" to reverse paralysis and repair tissue after severe spinal cord injuries.

11 Nov 2021

Exercises using virtual reality to relieve COVID breathlessness

A recent study evaluates an immersive virtual reality-based digital intervention to alleviate refractory breathlessness in patients recovering from COVID-19.

31 Oct 2021

FDA-approved drug encourages sensory neurons to regrow after injury

A spinal cord injury damages the lines of communication between the body and brain, impeding the signals that drive movement and sensation.

18 Oct 2021

Stringent lineage tracing is vital for nerve cell regeneration studies

UT Southwestern stem cell scientists find that stringent lineage tracing is crucial for studies of nerve cell regeneration. Their results, which are published in Cell, show that this tracing is far from routine in the field and suggest that earlier studies reporting "striking" regeneration results must be reexamined.

29 Sep 2021

Study shows resilience as a character trait to overcome spinal cord injuries

September is Spinal Cord Injury (SCI) Awareness month. According to the National Spinal Cord Injury Statistical Center, approximately 296,000 Americans are currently living with SCI, with around 17,900 new cases occurring each year.

25 Sep 2021

Small molecule drug can attenuate the triggers of neuroinflammation, preclinical study shows

Neuroinflammation can worsen outcomes in stroke, traumatic brain injury, or spinal cord injury, as well as accelerate neurodegenerative diseases like ALS, Parkinson's, or Alzheimer's. This suggests that limiting neuroinflammation may represent a promising new approach to treat neurological diseases and neuropathic pain that are driven by neuroinflammation.

24 Sep 2021

FB-EVAR is safe and effective for treatment of aortic aneurysms, study shows

A recent study revealed that endovascular repair of complex aortic aneurysms using fenestrated and branched endografts provides a safe and effective alternative to open surgical repair, with the lowest ever reported mortality rate in this patient population, according to researchers at The University of Texas Health Science Center at Houston and Memorial Hermann Heart and Vascular Institute Aortic Center.

10 Sep 2021

Study assesses the use of complementary and integrative healthcare by people with spinal cord injury

In a cross-sectional self-report study led by experts from five Spinal Cord Injury Model Systems Centers, a survey of people with spinal cord injury revealed that 80 percent of participants were current or previous users of complementary and integrative healthcare approaches such as multivitamins, massage, and acupuncture.

26 Aug 2021

Spinal Cord Injury News and Research

Further Reading

Drugs that block mineralocorticoid receptor may help protect bone cells during aging

‘Moving molecule’ therapy for severe spinal cord injury

Tighter blood pressure management may lead to better spinal cord injury recovery

Special bioactive scaffolds lead to greater functional recovery from spinal cord injury in mice

New therapy harnesses "dancing molecules" to reverse paralysis, repair tissue after spinal cord injuries

Exercises using virtual reality to relieve COVID breathlessness

FDA-approved drug encourages sensory neurons to regrow after injury

Stringent lineage tracing is vital for nerve cell regeneration studies

Study shows resilience as a character trait to overcome spinal cord injuries

Small molecule drug can attenuate the triggers of neuroinflammation, preclinical study shows

FB-EVAR is safe and effective for treatment of aortic aneurysms, study shows

Study assesses the use of complementary and integrative healthcare by people with spinal cord injury

Scientists restore memory in aging mice

Researchers identify reasons that prevent people with disabilities from seeking employment

New treatment targeting senescent cells boosts functional recovery from spinal cord injury

Many wheelchair users with spinal cord injury experience repairs and adverse consequences

Exoskeleton-assisted walking helps people with spinal cord injury evacuate stool more efficiently

New printable device could restore sight to blind people

Four-part small-molecule cocktail can prevent cellular stress

Topical drug regenerates, restores function of erectile nerves damaged by radical prostatectomy

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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