Status Epilepticus News and Research

RSS

Trial comparing three drugs for status epilepticus

Status epilepticus is a condition that is characterized by repeated seizures and is a medical emergency. Treatment is usually with a Benzodiazepine such as Diazepam or Lorazepam etc. There have been not any studies that look at the comparative benefit of drugs that could be prescribed for those who do not respond to the benzodiazepines. The study titled, “Randomized Trial of Three Anticonvulsant Medications for Status Epilepticus,” was published in the latest issue of the journal New England Journal of Medicine.

1 Dec 2019

Comparative study finds three anti-seizure drugs to be equally safe and effective

A new study finds that the three most common treatment options administered in the emergency department for patients who experience refractory status epilepticus are equally safe and effective.

27 Nov 2019

Emergency medicine doctors find better way to treat severe epileptic seizures in children

Emergency medicine doctors now have a better way to treat severe epileptic seizures in children, thanks to a New Zealand-Australian study.

19 Apr 2019

Training pediatricians to better diagnose and treat epilepsy

Imagine if most children with cancer were treated by a doctor with no training or experience in cancer. It doesn't seem possible. In epilepsy, however, it's more common than not.

4 Sep 2018

Study using i2b2 could help standardize artificial coma treatment for RSE patients

Status epilepticus, a dangerous condition in which epileptic seizures follow one another for a duration of five or more minutes without the victim's regaining consciousness between them, is the second most common neurological emergency in the United States, with a recorded maximum of around 150,000-plus cases per year.

30 Jun 2018

FDA approves cannabis based drug for severe form of epilepsy

The U.S. Food and Drug Administration (FDA) on the 25th of June 2018 approved Epidiolex oral solution that is essentially cannabidiol or the active component of marijuana or cannabis. As of now the drug is approved for use in two rare forms of epilepsy - Lennox-Gastaut syndrome and Dravet syndrome. The approval comes for individuals over two years of age.

28 Jun 2018

FDA approves new marijuana-based drug to treat rare and severe forms of epilepsy

The U.S. Food and Drug Administration today approved Epidiolex (cannabidiol) oral solution for the treatment of seizures associated with two rare and severe forms of epilepsy, Lennox-Gastaut syndrome and Dravet syndrome, in patients two years of age and older.

25 Jun 2018

UC receives $1.75 million grant for epilepsy research

Research scientist Jianxiong Jiang, PhD, doesn't just want to treat acquired epilepsy...he hopes to prevent it.

27 Feb 2018

UA scientist develops database to alert physicians about carbohydrate count in medications

A physician-scientist at the University of Arizona College of Medicine-Phoenix has developed a new database to ensure that individuals on ketogenic diets to help treat a certain kind of epilepsy are not prescribed potentially life-threatening medications that contain carbohydrates.

11 Feb 2018

Study provides insight into long-term health impact of convulsive seizures in children

Prolonged convulsive seizures in childhood could be linked to the development of other brain conditions, a study suggests.

7 Dec 2017

$Study shows population-based incidences, outcomes for refractory and super-refractory status epilepticus$

Study shows population-based incidences, outcomes for refractory and super-refractory status epilepticus

Three in four patients with refractory status epilepticus treated in an intensive care unit are still alive a year later, and half of them have recovered to baseline function, according to a new study from the University of Eastern Finland.

22 May 2017

Research shows potential way to limit damage to the brain caused by seizure disorder

Tiny vesicles isolated from adult mesenchymal stem cells and administered intranasally can limit the damage to the brain of animal models caused by a seizure disorder called status epilepticus, according to research published this week in the Proceedings of the National Academy of Sciences.

21 Apr 2017

Endocannabinoid system stimulation may be potential approach to treatment of epilepsy, study shows

In a study published in Brain Research, biophysicists from the Institute of Theoretical and Experimental Biophysics of the Russian Academy of Sciences and MIPT have shown that drug-induced activation of the endocannabinoid system of the brain leads to reduced or completely suppressed epileptic activity in test animals.

29 Mar 2017

$Study finds ketogenic diet as 'feasible' option for people with super-refractory status epilepticus$

Study finds ketogenic diet as 'feasible' option for people with super-refractory status epilepticus

In a small phase I and II clinical trial, Johns Hopkins researchers and colleagues elsewhere found that the high-fat, low-carbohydrate ketogenic diet was a safe and effective treatment option for the majority of adults experiencing a relatively rare, often fatal and always severe form of epilepsy marked by prolonged seizures that require medically induced comas to prevent them from further damaging the body and the brain.

27 Feb 2017

Estrogen-inhibiting drug may suppress dangerous brain seizures

A class of drug that inhibits estrogen production and is used to treat breast cancer has been found to quickly and effectively suppress dangerous brain seizures, according to a new Northwestern University study.

13 May 2016

Penn researchers report results of CAR therapy trial in brain cancer patients

Immune cells engineered to seek out and attack a type of deadly brain cancer known as glioblastoma (GBM) were found to have an acceptable safety profile and successfully migrate to and infiltrate tumors, researchers from Penn Medicine and Harvard University reported at the AACR Annual Meeting 2016.

19 Apr 2016

Article provides specific nursing considerations related to caring for patients experiencing prolonged seizure

Time is of the essence when a patient experiences a prolonged seizure, and immediate action is required to prevent long-term neurological damage, according to an article in the April issue of Critical Care Nurse.

4 Apr 2016

Drexel University researchers explore effective drug for treating established status epilepticus

Drexel University College of Medicine researchers are conducting an emergency medicine study to find out the most effective drug for treating established status epilepticus -- a life-threatening condition in which the brain is in a state of persistent seizure.

14 Mar 2016

AES releases new guideline to help physicians treat status epilepticus patients effectively

Status epilepticus - continuous or rapid sequential seizure activity for 30 minutes or more - is a medical emergency with a high mortality rate in both children and adults. Prompt and effective treatment is key; therefore the American Epilepsy Society has released a new guideline to help physicians, hospitals, and health systems treat patients effectively.

10 Feb 2016

Common mortality causes prevail in epilepsy patients

A prospective, community-based study confirms that patients with epilepsy usually die of the same causes as other people.

19 Jan 2016