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New insights into the cellular programs that promote resolution of inflammation during aging

Aging is associated with chronic, nonresolving inflammation, or "inflammaging," that can lead to tissue dysfunction.

6 Dec 2023

Study identifies key markers for early detection of fatty liver disease in obese and non-obese individuals

In a study published in 'Scientific Reports', researchers found that insulin resistance markers TyG-BMI and HOMA-IR effectively predict non-alcoholic fatty liver disease (NAFLD) risks in non-obese and obese individuals without diabetes, respectively. These findings suggest new, non-invasive methods for early NAFLD detection, particularly in atypical non-obese cases.

26 Nov 2023

Excessive diet soft drink consumption is associated with the occurrence of liver disease

The association between diet soft drink intake and metabolic dysfunction-associated steatotic liver disease (MASLD).

22 Nov 2023

New insights into the pathogenesis of chronic liver diseases

Fatty liver diseases (FLD) have become a significant health concern worldwide, affecting millions. The two most common types of FLD are non-alcoholic fatty liver disease (NAFLD) and alcoholic-associated liver disease (ALD). NAFLD is associated with obesity, insulin resistance, and metabolic syndrome, while ALD is caused by excessive alcohol consumption.

7 Nov 2023

Study reveals how formaldehyde alters gene expression through epigenetics

Epigenetics, the chemical mechanisms that controls the activity of genes, allows our cells, tissues and organs to adapt to the changing circumstances of the environment around us.

2 Nov 2023

Influence of healthy lifestyle habits on chronic disorders

The health benefits of regular exercise, a healthy diet, and adequate sleep.

2 Nov 2023

How African sleeping sickness melts away body fat: New study sheds light on the role of lipolysis

Researchers find that the T. brucei parasite, responsible for African trypanosomiasis, triggers weight loss by disrupting fat cell lipolysis. The study shows that ATGL enzyme is key to this process, potentially offering a new angle for future research and treatment.

17 Oct 2023

Impact of ketogenic diets on breast cancer

The therapeutic potential of the ketogenic diet (KD) for breast cancer (BC).

17 Oct 2023

The metabolic effects of endocrine therapy on diabetes mellitus in breast cancer survivors

Researchers discuss the history of endocrine therapies, highlights their adverse metabolic effects, and emphasizes the need for better biomarkers of diabetes.

5 Oct 2023

Fatty liver disease susceptibility: study identifies interaction between estrogen receptor and genetic variant in women

Researchers pursued evidence of whether the interaction between the patatin-like phospholipase domain-containing 3 p.I148M variant and the female sex at the genetic and molecular level explains why premenopausal women remain protected against fatty liver disease, while a rapidly progressive disease ensues in some peri- and postmenopausal women.

28 Sep 2023

Non-alcoholic fatty liver disease linked to higher risk of blood clots in healthy adults

Recent study in Scientific Reports finds a link between nonalcoholic fatty liver disease (NAFLD) and a higher risk of venous thromboembolism (VTE) among healthy Korean adults. The research suggests that NAFLD may contribute to a hypercoagulable state, increasing the risk of VTE.

27 Sep 2023

Genetic markers could help identify people at risk for metabolic dysfunction-associated steatotic liver disease

An astounding 30% of Americans currently have metabolic dysfunction-associated steatotic liver disease, or MASLD, which is formerly known as nonalcoholic fatty liver disease, or NAFLD.

27 Sep 2023

Coffee, fiber, and the Mediterranean diet are key players in fighting nonalcoholic fatty liver disease

Dietary patterns, foods, and nutrients to ameliorate nonalcoholic fatty liver disease (NAFLD).

19 Sep 2023

Are energy drinks putting your heart and mind at risk?

Comprehensive review finds energy drinks linked to range of health risks, from cardiac arrhythmias to mental health issues. Researchers call for strict regulations on their consumption, especially among minors and pregnant women.

12 Sep 2023

Exploring the role of the metabolic syndrome in individual mechanisms of liver fibrosis

Chronic liver injury results in the development of liver fibrosis in approximately 25% of individuals in response to diverse insults, and several aspects of the development of liver injury appear to be common to a variety of initiating factors.

31 Aug 2023

Study identifies an endogenous bile acid that alleviates non-alcoholic fatty liver disease

A study finds that hyodeoxycholic acid alleviates non-alcoholic fatty liver disease by modulating the gut-liver axis.

22 Aug 2023

Meta-analysis reports global prevalence of MAFLD of 38.8% in adults

Non-alcoholic fatty liver disease (NAFLD) is a common condition that affects up to 30% of adults in the general population.

18 Aug 2023

Pecans may help prevent obesity and reduce inflammation, study shows

Daily consumption of pecans have been shown to prevent obesity and a host of related health issues like fatty liver disease and diabetes, according to a collaborative study by Texas A&M AgriLife scientists.

1 Aug 2023

Understanding the developmental link: vitamin D's role in metabolic disease risk

Study showed that transplanting fetal hematopoietic stem cells exposed to vitamin D deficiency induces diabetes.

14 Jun 2023

Using ex vivo gene therapy to fight obesity and diabetes in mice

A scientific team from the University of Barcelona and the CIBERobn has designed a strategy to fight obesity and diabetes in mice through ex vivo gene therapy which consists of implanting cells that have been manipulated and transformed in order to treat a disease.

30 May 2023